促肝细胞生长素治疗早期肝硬化50 例临床观察.pdf

中国医创Q年7L第鲞箜C堕』1．22067促肝细胞生长素治疗早期肝硬化5O例临床观察李银忠张志国李树军临床研究【摘要】目的探讨促肝细咆生长素HGF对早期肝硬化的治疗作用。方法用促肝细胞生长素静脉滴注治疗早期肝硬化5O例治疗组每EL100MG促肝细胞生长素加入10％葡萄糖注射液250ML缓慢静脉滴注。对照组39例给予常规治疗。结果经过4周一个疗程后治疗组的丙氨酸氨基转移酶A、胆红素SB比治疗前显著降低P0．05。清蛋白、凝血酶原活动度等指标比治疗前明显升高尸0．05。对照组治疗前后无明显改变。结论HGF治疗早肝硬化有明显疗效。【关键词】促肝细胞生长素；早期肝硬化；治疗ACLINICALOBSERVATIONONTREATMENTOFCOMPENSATEDLIVERCIRRHOSISBYHEPATOCYTEGROWTHPROMOTINGFACTORSIN50CASESLIHNZHONG，ZHANGZHIGUO，LISHUJUN．TCMHOITALOFYA，N，RAIN453200，CHINA【ABSTRACT】OBJECTIVETOINVESTIGATETHETHERAPEUTICEFFECTSOFHEPATOEYTEGROWTHPROMOTINGFACTORSONCOMPENSATEDLIVERCIRRHOSIS．METHODSHEPATOCYTEGROWTHPROMOTINGFACTORSWASADMINISTRATEDINTRAMUSCULARLYINDOSAGEOF100MGADDLO％GS250MLGTTINTRAVENOUSLYGUTTAESLOWLYPERDAYTO50PATIENTSWITHCOMPENSATEDLIVERCIRRHOSIS．OTHER39CONTROLCASESWEREGIVENREGULARTHERAPY．RESULTSATTHEENDOFFIRSTTHERAPEUTICCOURSEWITHHEPATOCYTEGROWTHPROMOTINGFACTORS，SIGNIFICANTREDUCTIONINALTANDSBP005，INCREASEINALBUMINANDPTAP005．CONCLUSIONACLINICALOBSERVATIONONTREATMENTOFCOMPENSATEDLIVERCIRRHOSISBYHEPATOCYT