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灯盏细辛注射液联合依那普利治疗慢性肾小球肾炎疗效观察.pdf

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灯盏细辛注射液联合依那普利治疗慢性肾小球肾炎疗效观察.pdf

NULL‚NULLNULLNULLVŒA†GŸ/LO/R4徐NULL宏广西中医学院第三附属医院,广西柳州545001NULLNULLK1NULL目的NULL观察灯盏细辛注射液联合依那普利治疗慢性肾小球肾炎的临床疗效B方法NULL将83例慢性肾小球肾炎患者随机分为2组,对照组42例予依那普利治疗,治疗组41例在对照组治疗基础上予灯盏细辛注射液治疗B2组均以14D为1个疗程,治疗2个疗程后评定疗效B检测2组治疗前后24H尿蛋白定量UPROA血尿素氮BUNA血肌酐SCR变化情况B结果NULL治疗组上述指标与治疗前及对照组治疗后比较均有显著性差异P均005,治疗组总有效率明显高于对照组P005B结论NULL灯盏细辛注射液与依那普利联用可减少尿蛋白排出,改善肾功能,适用于治疗慢性肾小球肾炎B1OMNULL灯盏细辛;依那普利;慢性肾小球肾炎MS|NULLR069231NULLNULLNULLDSM’NULLANULLNULLNULLCI|NULL10088849201025313703OBSERVATIONOFCURATIVEEFFECTOFERIGERONBREVISCAPUSINJECTIONCOMBINEDWITHENALAPRILONCHRONICGLOMERULONEPHRITISXUHONGTHETHIRDAFFILIATEDHOSPITALOFGUANGXICOLLEGEOFTCM,LIUZHOU545001,GUANGX,ICHINAABSTRACTOBJECTIVEITISTOOBSERVETHECLINICALCURATIVEEFFECTOFERIGERONBREVISCAPUSINJECTIONCOMBINEDWITHENALAPRILONCHRONICGLOMERULONEPHRITISMETHODS83CASESOFPATIENTSWITHCHRONICGLOMERULONEPHRITISWERERANDOMLYDIVIDEDINTO2GROUPSTHECONTROLGROUP42CASESWASGIVENENALAPRI,LANDTHETREATMENTGROUP41CASESWASTREATEDWITHERIGERONBRENULLVISCAPUSINJECTIONONTHEBASISOFCONTROLGROUPNULLSTREATMENT24HURINARYPROTEINQUANTITATIVEUPRO,BLOODURIANITROGENBUNANDSERUMCREATININESCRBEFOREANDAFTERTREATMENTINBOTHGROUPWEREOBSERVEDRESULTSCOMPAREDWITHTHATBENULLFORETREATMENTANDINCONTROLGROUPAFTERTREATMENT,THEINDEXESABOVEINTREATMENTGROUPAFTERTHERAPYWERESIGNIFICANTLYDIFFERNULLENTALLP005THETOTALEFFECTIVERATEINTREATMENTGROUPWASOBVIOUSLYHIGHERTHANTHATINCONTROLGROUPP005CONCLUSIONERIGERONBREVISCAPUSINJECTIONCOMBINEDWITHENALAPRILCANDECREASETHEEXCRETIONOFURINARYPROTEIN,IMPROVETHERENALFUNCTION,ANDISSUITFORTHETREATMENTOFCHRONICGLOMERULONEPHRITISKEYWORDSERIGERONBREVISCAPUSINJECTION;ENALAPRI;LCHRONICGLOMERULONEPHRITIST€ENULL徐宏1970,男,副主任医师,研究方向为中西医结合防治继发性肾脏疾病BNULLNULLŸ/LO/EŸ/‘UAUAA5VC,HZT‚,HF,HMZ,V‚/H|,K|ZŸ/šBF/LOHBH,HF˜,’4,B2008M12010M1,3€PVŒAGŸ/€41,RTZ,C/B1NULL51NULL1NULLBNULL4/SŸ/€83,˜†Ÿ/S1,H116ABS2FF41,322,O19;M1270331213BVF42,324,O18;M1469304253B2F€ŸYAMHZAŸSP005,V1ŸB1NULL2NULLZENULL2F€D8†,“∀A‘‚J;|E130/80MMHG1MMHG0133KPA/,I/š5‘‚J,žA™Y;∃AE™,I0}R150300MG/DA”ŸG1020MG/Q1QG›,Fƒœ4,†RT‚X,5FBDBFVŒA23V0ZK3,S03Z5302156930MLF5A250ML,1Q/D,14D1,2B1NULL3NULL4SNULLA1SYBAAAU‹BUNASCR,243137C}D†MODERNJOURNALOFINTEGRATEDTRADITIONALCHINESEANDWESTERNMEDICINE2010SEP,1925HUA24HU‘UPRO,H40W‚Q‹B1NULL4NULLRSNULL•VD2Ÿ/RSEB›†8˜›†H,U‘_|Ÿ2,24HU‘02G,/UH,U9”/žB8˜H,U‘_H50,/U‚V3,U9”ž,/žžžM‚V15BR8˜AZ,U‘_H1,24HU‘H2549,/U‚V5,/žBR5LI_AQFB›†F9ARB1NULL5NULLD9NULLT”SXS„SQVU,SPSS110D9Q,9T_,9”NULL2_B2NULLNULLNULLT2NULL1NULL2F4S1NULLV1,FUPROABUNASCRA/†P005,7VFSCR/†P005BFSVF1AŸSP005,NV1B表1NULL2组治疗前后各项指标比较XSFYNHWUPRO/G/DBUN/MMOL/LSCR/NULLMOL/LVF422201151501321825477112137418484571563511∀F41210106097047∀1967363587235∀19414561209473∀NULLNULL∀F1,P005;VF1,P005B2NULL2NULL2FR1NULLF9RQAVFP005,NV2B表2NULL2组临床疗效比较例FYNARRR9RVF421330133116382662F412971922373892∀NULLNULL∀VF1,P005B2NULL3NULL2F‚Q‹3Fƒ1NULLFVNLAPTAAPTTS,C‘A,OŸ€NM,€›1BF5CU,VF3CU,Œ0SB2FCKB3NULLNULLNULL‚Ÿ/HY„,SYF,HMZA‚˜/LOŸKŸM,K|Ÿ/‚†B•YHFZYZ,‘UŸ/15VC,Ÿ‘U,PHF4,‘UV/LO—,/HM1BYB‘UY/LOS/LO5M73,Q˜/LO,IV„/L5A/W8,P/HM›ŸZ,/V1BC}D3,/HM™1Y,8‘T,9/LO8AB/3P1,4U/†PŸH,HM‚K/F,VN“B/H/H,V,BN“,/5FDRASŸ/LO—A/W8™Z1TBCX5F4ACEI/KR0,V‘U/HUH/H,/ZRABGBSŸš˜RAS4,YV5FACE,E5F5F∋,I„S,H73FTBACEIZ†T“,2T,TB,/∀ACEIE5F∋3,H5L,E„3,H,V7Rž†DTBACEIV”F/LOOL,O”FOLTOL,†/LO,H—I/†/LO—,/ZBH/LO“,H/LO—ZB∃†/LORVYIŸ,HU‘RB0VŒV,SOF†BVŒ,M,Ÿ,|AEA„AVEA}YŽBVŒAVŒ4|04,RS1,”F5AA9FF9AAMŸ}†T4BDD,|EŸ/,HSH,Ÿ/3AZ‚VJTB54AUVŒAV/,/‚†Z,/H57BL9L,VŒVA8“89‹†,VA/HM,H‘U,Y0„F3Y0VR,V7/W8ŸLC/T810B6“,‘U/HZ“1BY,VF„/L5WBVŒVAH/H€‘U,6}‘,žS,/LO—W8,/‚†ZBTAU,GVŸ/€UPNULLROABUNASCR,VŒARTA,YV€†;†Sž/LO/31433138C}D†MODERNJOURNALOFINTEGRATEDTRADITIONALCHINESEANDWESTERNMEDICINE2010SEP,1925表3NULL2组治疗前后及正常人肱动脉超声检查结果比较XSFYN/MMFMD/NMD/F37368070373065407214∀897209∃17714801801531VF37372066375063410211∀612213∗17984091817542žF3638007910003011900583NULLNULL∀žF1,P001;1,P001;∃VF1,P001;∗1,P005B„M,5GŸ}F1M,‚ZE7,Z’„Ÿ,OVWQ˜39BTV,€RIGŸ}FH,5Œ12,€UQ‹Ÿ”FFMDA9V,5Œ€5GŸ}F,F0V|RŒRTB5ŒNULLS8E4KF4,VYVFT7žR10BYVFKH„4B„L,S5ŒM3H€,‚AHŒ,7OV5GŸ}F,€{ŸMBMŸ,S€,5ŒH,€VNULLS8E{ŸM“,V1ANULL2S8E„FŸ{ŸM,€4R1112BO‚DD4ŸNULLS8E4,A}†“5•YML,V†‹M3H€B•ID1NULLZD2009NULLS8E45LLJšPNSD‚,20091029C14152NULL1Y,I5Œ3HŒQMSŸ•YJD0,2008,27139423NULLI†NULLS8E4J‚BJ,2004,1264814824NULLS,B,,5HM†GS/Œ,20034204215NULLFXS,,RR,ŒM_J5,2003,1213116NULLDMDDMDRBMSYPJMD,1996,15197NULLCELEMAJERDSTESTINGENDOTHELIALFUNCTIONUSINGULTRASOUNDJJCARDIOVASEPHARMACO,L1998,32SUPPLS29S328NULL55HNSD‚,20080911C149NULL5JSLS,2009,29978378610,,5ŒŸš€5Y0•YJS,2004,193194197115Œ5D4RNSD‚,20070531A1212NULLS8E45H‹EM,ƒNSD‚,20090604C12LNULL2010020431389A„RV,†€,P/„1BYN,3€Ÿ/,VŒAG†‹RTZ,O5‹†,YS,WB•ID1NULL,D‡SM63,20045045052NULLSED050055MSD0S/,20022032373NULL1,3,A,D5/HMSD0,19971201224NULLC0JZMSD0S/,199322905NULL„Y,VŒA/S5‹J5D0LL,2004,131356NULL,ZVŒ5H„/H5‹JD,2005,744764777NULLFS‡,,D0Ÿ/8JSD†/H,2003,45308NULL‡,,J‡,VŒAVŠ/W8•YJSD†,2008,2821421459NULLF,F,ž,89„‹†•YJS0,1999,341066866910L,,},VLY333531UHVŠ/TJ/H,2004,206429433LNULL201003103143C}D†MODERNJOURNALOFINTEGRATEDTRADITIONALCHINESEANDWESTERNMEDICINE2010SEP,1925

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