双歧杆菌四联活菌片联合复方谷氨酰胺肠溶胶囊治疗老年人肠道菌群失调相关性腹泻的临床观察.pdf

)Z!5M)M154闫null翔,范惠民,刘null芳(解放军成都军区总医院老年病科,四川成都610083)nullK1nullnull观察双歧杆菌四联活菌片(商品名:思连康)联合复方谷氨酰胺肠溶胶囊对老年人肠道菌群失调相关性腹泻的临床疗效bZEnull肠道菌群失调相关性腹泻老年住院患者68例,根据随机数字表法按入院先后顺序随机分为治疗组和对照组各34例,治疗组服用双歧杆菌四联活菌片1g加复方谷氨酰胺肠溶胶囊0null4g,均3次/天；对照组仅服用双歧杆菌四联活菌片1g,3次/天,比较两组总有效率及粪检结果bTnull治疗组显效28例a有效5例a无效1例,总有效率为97null05%；对照组显效16例a有效10例a无效8例,总有效率为76null47%,两组总有效率比较差异有统计学意义(P0null05)；两组粪检杆球比例倒置a细菌计数减少a真菌感染等差异均有统计学意义(P0null05)bnull双歧杆菌四联活菌片联合复方谷氨酰胺肠溶胶囊治疗老年人肠道菌群失调相关性腹泻,疗效确切,安全可靠bnull1oMnull复方谷氨酰胺；双歧杆菌四联活菌；菌群失调；腹泻nullms|R574null4nullnullnullnullnullnullnullnullDSMAnullnullnullnullnullnullnullnullcI|1672null6170(2010)05null0082null02ClinicalobservationonCombinedBifidobacteriumandCompoundGlutaminEntresolunullbleCapsulesforelderlypatientswithalterationofintestinalfloranullYANXiang,FANHuinullmin,LIUFang(DepartmentofGeriatrics,GeneralHospitalofPLAChengduMilitaryRegion,Chengdu610083,China)nullAbstractnullObjectivenullToobservethetherapyofCombinedBifidobacteriumandCompoundGlutaminEntresolubleCapnullsulesforelderlypatientswithalterationofintestinalfloranullMethodsnullAtotalof68patientswithalterationofintestinalflorawererandomlydividedintotheexperimentalgroupandthecontrolgroup,with34patientsineachgroupnullThetreatmentgroupwastakenCombinedBifidobacterium1gandCompoundGlutaminEntresolubleCapsules0null4g,3times/dnullThecontrolwastakenComnullbinedBifidobacterium1g,3times/dnullTheresultswerestatisticallyanalyzedbySPSS13null0nullResultsnullResultswereexcellentin28cases,effectivein5casesandineffectivein1casenullTheeffectiveratewas97null05%nullInthecontrolgroup,theresultswereexcelnulllentin16cases,effectivein10casesandineffectivein8casesnullTheeffectiveratewas76null47%nullThedifferencebetweentwogroupswassignificantinallthedetectedindicators(P0null05)nullConclusionnullThetherapyofCombinedBifidobacteriumandCompoundGlutaminEntresolubleCapsulesforelderlypatientswithalterationofintestinalfloraiseffective,safeandreliablenullnullKeywordsnullCompoundglutamine；CombinedBifidobacterium；Dysbacteria；DiarrheanullnullF)0,/?y,M?h|,)M1?3tA91,534),M*p|,h,B34Hr.b2006M,)Z!5M)M1,|i5rT,C/b1nullZE1null1nullBnull2006M12010M1hM68,(/)M1S2:!ane,Qv3Q,vLvL*AL；L%)p4U%)9h,|)o)1,l1(10null1)；#%)_)/),L!$o)av)Q)；F)0-y；%)hPF)0b3VE5sFvF34bF330,o4,M-7296,(80null83&10null05),d18,U11,5；vF329,o5,M-7395,(80null03&10null75),d24,U8,2bPF)01:haSvabFM-aYa?%h1,s(d9il(P0null05),nV1b82nullLD52010M975nullV1nullFLS1FYnY(n)3oM-()?%h(n)dUF3430480null83&10null0518115vF3429580null03&10null752482d9null2=0null128t=-0null024null2=2null617P0null7200null9810null2701null2nullZEnullFZ!5(v0,vL,12Q；r:nh,Lh,2Q；r:nM,vLQaMb1null5nulld9ZEnull(SPSS13null0d9qsb9(&SVU,FW1t_；9null2_bPD0null05sd9ilb2nullT2null1nullF9rq1nullF9rq97null06%,vF9rq76null47%,F1sd9il,nV2bV2nullF9rq1FYArn(%)rn(%)rn(%)9rq(%)null2PF3428(82null35)5(14null71)1(2null94)97null06vF3416(47null06)10(29null41)8(23null53)76null4710null3840null0062null2nullF_T1nullF_o1a%)9ha)1,s(d9il,nV3bV3nullF_T1nulln(%)FYo1%)9h)F342(5null88)1(2null94)1(2null94)vF349(26null47)10(29null41)9(8null82)null25null3148null7857null503P0null0210null0030null0062null3nullQnull0F(?C?a?a/?asM,VnTb3null)M),)a)Ah,HyQaPb734y),y3pr,XTF3M1)$EbM*,*f,p?,F?h,3,.?3%)/=,C%)=,l,*,*#?,MF3M1)9A13bZ!5B*4,Lnull!0FbLnull!B+y,*%1?#Af!4b0$Zbma%,1Aar,2Aar,0bZ4m,rrbyN,Z!5#*,9M1y3#ZrTz,?CQ,5wbnullID1曹艳菊,屈昌民,袁群,等null老年人抗生素相关性肠道菌群失调的防治Jnull胃肠病学和肝病学杂志,2005,14(2):195null199null2中华人民共和国卫生部null医院感染诊断标准(试行)Mnull北京:中华人民共和国卫生部,2001null3