分子生物学.ppt

分子生物学MolecularBiology,ZhaoWANG(王钊),M.D./Pharm.D.SchoolofLifeScienceTsinghuaUniversityBeijing,100084Tel41Emial:,IntroductionofMyself,王钊（药学博士），中药研究所主任医学药学生物学研究方向：1.中药的分子细胞药理学2.中药（复方）药代动力学3.细胞凋亡的分子机制4.天然药物的研制与开发,IntroductionoftextbookGeneVII,IntroductionoftextbookGeneVII,Anextensivelyupdatedandrestructuredcontenttoreflectmodernthinking;Revisedlayoutwhichpresentsthemostcurrentresearchevenmoreclearlyandconcisely;Directanalysisofthegenomeintermsofitscontentofgenes;Over800fullcolourgraphicstoillustrateimportantconcepts;Overviewfiguresthatsummarizelargeamountsofwork;Freeaccesstoallillustrationsonoup/genesvii,makinglearningandteachingfromthisbookeveneasier.,PrefacetotheGeneVII,分子生物学教学大纲,第一章绪论第二章DNA蕴藏全部生物信息第三章DNA的周而复始第四章从基因到蛋白质第五章原核生物基因表达第六章真核生物基因组第七章真核生物基因表达与调控第八章基因的分离与DNA技术第九章结尾,GenesVIIContents,1GenesareDNA15Transposons2Fromgenestogenomes16Retrovirusesandretroposons3Howmanygenesarethere?17RearrangementofDNA4Clustersandrepeats18Chromosomes5MessengerRNA19Nucleosomes6Proteinsynthesis20Initiationoftranscription7Usingthegeneticcode21Regulationoftranscription8Proteinlocalization22NuclearsplicingandRNAprocessing9Transcription23CatalyticRNA10TheOperon24Immunediversity11Phagestrategies25Proteintrafficking12Thereplicon26Signaltransduction13DNAreplication27Cellcycleandgrowthregulation14Recombinationandrepair28Oncogenesandcancer29Gradients,cascades,andsignalingpathways,分子生物学常用参考书目,1MolecularBiologyoftheCell(4thEditionbyBAlberts)2MolecularCellBiology(4thEditionbyHLodish)3MolecularBiology(2ndEditionbyRWeaver)4分子生物学(InstantNotesinMolecularBiology,2ndEditionbyPTurner）5AdvancedMolecularBiology(byRTwyman)6现代分子生物学（朱玉贤等）,分子生物学实验参考书目,1.分子克隆实验指南2.精编分子生物学实验指南3.PCR技术实验指南4.分子生物学实验基础5.细胞工学实验方案6.现代分子生物学实验技术7.分子生物学实验技术8.分子生物学基础技术,分子生物学主要参考杂志,Cell37.297ChineseMedicalJ.0.127FASEBJ.14.629JofExperimentalMedicine14.384JofNaturalProducts1.432JofPharmacologicalScie