以髓芯减压为基础“保髋”治疗早中期股骨头坏死.doc

“” ;(osteonecrosis of the femoral headONFH)1-6ONFH7ONFHONFH8ONFH1 ONFH9ONFH2 ONFH“”10-111265(80)40ONFHONFHONFH1346(58)Ficat (A)25Harris83.3%Harris615851441(50)3ONFHHarrisXONFHONFH15ONFH17(18)1317194.4%1687(114)ONFHFicat ()ONFH;Ficat ()3 17ARCOONFH19(19)2419Harris921813(13)ONFH(Steinberg)Harris(76.1±5.2)361218X1942(47)24(26)18(21)1(P < 0.05)2036(45)15(19)21(26)12Harris(P < 0.05)4 5 “”“”“”“”296580Ficat63669.2%88.9%305634()22()(P < 0.05)31ONFH78(96)39(P < 0.05)(P < 0.05)(P < 0.05)3268(82)(15 g30 g15 g10 g20 g12 g12 g10 g10 g10 g10 g10 g)3191.46%6 ONFHONFHONFHONFH“”1 .J.201030(1)3-5.2 Wei BFGe XH.Treatment of osteonecrosis of the femoral head with core decompression and bone graftingJ.Hip Int201121(2)206-210.3 Eward WCRineer CAUrbaniak JRet al.The vascularized fibular graft in precollapse osteonecrosisis long-term hip preservation possible?J.Clin Orthop Relat Res2012470(10)2819-2826.4 Gangji VDe Maertelaer VHauzeur JP.Autologous bone marrow cell implantation in the treatment of non-traumatic osteonecrosis of the femoral headFive year follow-up of a prospective controlled studyJ.Bone201149(5)1005-1009.5 Liu YLiu SSu X.Core decompression and implantation of bone marrow mononuclear cells with porous hydroxylapatite composite filler for the treatment of osteonecrosis of the femoral headJ.Arch Orthop Trauma Surg2013133(1)125-133.6 Zhao DCui DWang Bet al.Treatment of early stage osteonecrosis of the femoral head with autologous implantation of bone marrow-derived and cultured mesenchymal stem cellsJ.Bone201250(1)325-330.7 Chan PKCheung THLi WHet al.Attribution of human papillomavirus types to cervical intraepithelial neoplasia and invasive cancers in Southern ChinaJ.Int J Cancer2012131(3)692-705.8 Chang JTKuo TFChen YJet al.Highly potent and specific siRNAs against E6 or E7 genes of HPV16-or HPV18-infected cervical cancersJ.Cancer Gene Ther201017(12)827-836.9 .J.200527(1)88-89.10 .J.201024(3)266-269.11 .J.201032(2)86-88.12 .J.200625(3)382-384.13 .J.201331(2)217-219.14 .J.20148(5)578-584.15 .J.200729(2)28-29.16 .J.201226(10)1165-1168.17 .J.201216(11)43-45.19 .J.20129(16)187-188.20 .J.201216(29)5501-5505.21 Hernigou PBeaujean FLambotte JC.Decrease in the mesenchymal stem-cell pool in the proximal femur in corticosteroid-induced osteonecrosisJ.J Bone Jiont Surg Br199981(2)349-355.22 Bennett M.Hyperbaric oxygen therapy improved both pain scores and range of motion in patients with early idiopathic femoral head necrosis (Ficat stage )J.Diving Hyperb Med201141(2)105.23 Balla BPintér CKósa JPet al.Gene expression changes in femoral head necrosis of human bone tissueJ.Dis Markers201131(1)25-32.24 .J.201216(4)748-751.25 .J.201233(10)1802-1803.26 .J.20