IVF各种率的计算.doc

采卵周期（Aspiration cycle）：initiated ART cycle in which one or more follicles are punctured irrespective of whether or not oocytes are retrived.在启动周期中穿刺获得大于等于1个卵泡的周期数（不论是否获得卵母细胞）胚胎移植周期（embryo transfer cycle）：一个或多个胚胎移入宫腔或输卵管内的周期数。临床妊娠clinical pregnancy：evidence of pregnancy by clinical or ultrasound parameters (ultrasound visualization of a gestation sac). It includes ectopic pregnancy. Multiple gestational sacs in one patient are counted as one clinical pregnancy. B超下看到孕囊或其他临床证据证实妊娠。包括异位妊娠。一个患者看到多个孕囊计为一个临床妊娠。临床妊娠率clinical pregnancy rate：number of clinical pregnancies expressed by 100 initiated, aspirated, or embryo transfer cycles .when clinical pregnancy rates are given, the denominator(initiated, aspirated, or embryo transfer cycles) must be specified.每100个启动周期或取卵周期或胚胎移植周期临床妊娠数（如果定义此率应注明分母是启动周期？取卵周期？胚胎移植周期？）种植率implantation Rate =B超下见到孕囊数（包括异位妊娠经活检提示有胚胎植入的证据，或诊刮提示有滋养细胞）/ 移植胚胎数。分娩率Delivery Rate: Number of deliveries expressed by 100 initiated, aspirated, or embryo transfer cycles. When delivery rates are given, the denominator(initiated, aspirated, or embryo transfer cycles) must be specified. It includes deliveries that resulted in a live birth and/or stillbirth. The delivery of a singleton, twin or other multiple pregnancy is registered as one delivery.每100个启动周期或取卵周期或胚胎移植周期分娩数。如果定义此率应注明分母是启动周期？取卵周期？胚胎移植周期？包括活产的分娩和或死产的分娩。单胎、双胎或多胎都计为一次分娩。分娩（出生）：胎儿完全从母体排出或取出，不论脐带是否已剪断或者胎盘是否附着在子宫。体重低于500g的胎儿不易存活，从围产期统计看不算出生。如未测出体重时，以胎龄20-22周相对于500g计算。若未测出生体重，又不知胎龄是否在20-22足周，则以身长（头顶到足跟长）25cm相当于500g计算。出生时有生命：当婴儿出生时有呼吸或显示了任何其他生命迹象，如心跳、脐带波动或者明确的随意肌活动时，算是有生命。活产：出生后有生命迹象的分娩过程 活产分娩率（live-birth delivery rate）Number of live-birth deliveries expressed by 100 initiated, aspirated, or embryo transfer cycles. When live-birth delivery rates are given, the denominator(initiated, aspirated, or embryo transfer cycles) must be specified. It includes deliveries that resulted in a live birth and/or stillbirth. The delivery of a singleton, twin or other multiple pregnancy is registered as one delivery. 活产分娩次数（单胎、双胎、多胎算一次分娩次数）分母可以为100个启动周期、100个取卵周期、或者100个移植周期。如果定义此率应注明分母是启动周期？取卵周期？胚胎移植周期？计数至少有1个活产的分娩次数。单胎双胎或多胎都计为一次分娩抱婴回家率 分子活产分娩次数（单胎、双胎、多胎算一次分娩次数）分娩7天内新生儿死亡事件数。如果定义此率应注明分母是启动周期？取卵周期？胚胎移植周期？）初期新生儿死亡Early neonatal death ：death occurring within the first 7 days after delivery.活产婴儿在出生开始的足7天内死亡。晚期新生儿死亡：活产婴儿出生7天后到足28天内死亡受精率（fertilization rate）受精数（正常受精异常受精延迟受精（晚期卵裂？）/用于受精卵子数（ICSI时为脱颗粒后MII数）卵裂率（cleavage rate）移植当天有卵裂的胚胎数（不包括异常受精卵子分裂来的卵裂球）/正常受精卵子数（包括受精当天没有看到原核，第二天卵裂的胚胎） 受精率（fertilization rate）受精数（正常受精异常受精延迟受精（晚期卵裂？）/用于受精卵子数（ICSI时为脱颗粒后MII数）ICSI受精数的计算是否也是正常受精（2PN）异常受精(1PN,3PN)延迟受精（0PN晚期分裂）？临床妊娠率的分母是新鲜周期有移植的周期数IVF受精率=(2PN+1PN+多PN+晚期卵裂）/获卵数ICSI受精率=(2PN+1PN+多PN）/MII卵子数这个是卫生部给的计算公式，你可以参考下抱婴回家率的分母也应该是移植周期数卵裂率（cleavage rate）移植当天有卵裂的胚胎数（不包括异常受精卵子分裂来的卵裂球）/正常受精卵子数（包括受精当天没有看到原核，第二天卵裂的胚胎） 按你这么说受精当天没有看到原核，第二天卵裂的胚胎属于正常受精罗？那分子中包不包括这类胚胎呢？到底是2PN卵裂数/2PN+0PN（即晚期卵裂）受精数，还是2PN+0PN卵裂数/2PN+0PN受精数？谢谢各位给的答复，我也是初学者，有些问题大家一起探讨。有关临床几个率的计算，我是从外文一本参考书上翻译下来的。可能和国内的，卫生部给的标准是不一样的。 看来大家都倾向于认为分母是新鲜周期有移植的周期数？至于受精率和卵裂率，我没有看到很标准的完整的定义。如果卫生部有准确的定义，欢迎大家及时贴上来。把错误的指出来大家共同进步。呵呵IVF受精率=(2PN+1PN+多PN+晚期卵裂）/获卵数ICSI受精率=(2PN+1PN+多PN）/MII卵子数这个是卫生部给的计算公式，你可以参考下 还有别的卫生部的规定吗？一起贴上来有关继续妊娠率on going pregnancy rate is also a usefull outcome, which has not been difined consisitently but refers to a pregnancy that is less likely to end in miscarriage. The likelihood of miscarriage declines with increasing gestational age and is significantly reduced after 10 weekss gestation .Thus，ultrasonography done at 12 weeks gestation showing evidence of cardiac activity in a fetus that is at the appropriate size for gestational age should be used to confirm that the pregnancy is ongoing