细胞周期和细胞凋亡类基因

细胞周期和细胞凋亡类基因G0G1转变(G0toG1transition)1:mdm4G1/S特异转录，有丝分裂细胞周期(G1/S-specifictranscriptioninmitoticcellcycle)1:gfi1G1/S转变,有丝分裂细胞周期(G1/Stransitionofmitoticcellcycle)19:bcat1ccnd1ccne1cdc34cdc7cdca5cdk4cdkn3cul1cul2cul3cul4acul5gspt1lats2pmlppp6crcc1skp2G1/S转变检控点(G1/Stransitioncheckpoint)4:dlg1hus1nbnpuraG1期(G1phase)2:cdc42rb1G1期,有丝分裂细胞周期(G1phaseofmitoticcellcycle)10:anapc2cdc23cdk6cdkn1cdnaja2e2f1map3k11taf1taf1ltbrg4G1特异转录，有丝分裂细胞周期(G1-specifictranscriptioninmitoticcellcycle)1:gfi1bG2/M转变,有丝分裂细胞周期(G2/Mtransitionofmitoticcellcycle)10:anapc10anapc4anapc5birc5ccnb1cdk2dnm2khdrbs1lats1tpd52l1G2/M转变DNA损伤检控点(G2/MtransitionDNAdamagecheck-point)1:brsk1G2期,有丝分裂细胞周期(G2phaseofmitoticcellcycle)4:cenpfches1gtse1kpna2M期(Mphase)2:ilf3rb1M期,有丝分裂细胞周期(Mphaseofmitoticcellcycle)4:cdc25bdlg7mphosph6mphosph9M期特异微管过程(Mphasespecificmicrotubuleprocess)1:kpna2S-M检控点(S-Mcheckpoint)1:appbp1S期,有丝分裂细胞周期(Sphaseofmitoticcellcycle)1:cdk2ap1S期特异转录，有丝分裂细胞周期(S-phase-specifictranscriptioninmitoticcellcycle)1:abl1胞裂蛋白环组装(septinringassembly)1:nubp1胞质分裂(cytokinesis)16:arhgef11aurkccecr2dctn3diaph2espl1myh10prc1rasa1rock2sept2sept3sept4sept5sept6sept7不对称细胞分裂(asymmetriccelldivision)1:pard3凋亡程序(apoptoticprogram)10:badbikcasp2casp7casp8casp9mcl1pdia2psen2vdac1凋亡核改变(apoptoticnuclearchanges)2:dedd2ndufa13凋亡染色体浓缩(apoptoticchromosomecondensation)1:acin1凋亡线粒体改变(apoptoticmitochondrialchanges)4:bak1baxbcl2l1bid动粒组装(kinetochoreassembly)2:cenpecenpf纺锤体组织和生物发生(spindleorganizationandbiogenesis)7:aurkabub1bcks2kntc2spag5ube2czwint分裂间期,有丝分裂细胞周期(interphaseofmitoticcellcycle)1:katna1减数分裂(meiosis)30:bollc8orf1ccna1ccnb3cspg6dmc1dmwddusp13exo1h2afxmre11amsh4msh5nek2rad50rad51rad54lrec8l1smc1l1smc1l2spo11stag2stag3sycp1sycp2top3atsga2utp14cxrcc2zw10减数分裂纺锤体组织和生物发生(meioticspindleorganizationandbiogenesis)1:tubg1减数分裂前期I(meioticprophaseI)1:sycp2减数分裂前期II(meioticprophaseII)1:msh5减数分裂染色体凝集(meioticchromosomesegregation)1:sgol1减数分裂重组(meioticrecombination)19:atmchek1dmc1klhdc3lig3mlh3mre11amsh4msh5rad21rad50rad51rad51l1rad51l3rad52rad54brec8l1spo11sycp1姐妹染色单体凝集(sisterchromatidsegregation)1:lats1姐妹染色单体连接(sisterchromatidcohesion)3:cspg6polsrec8l1跨越开始控制点,有丝分裂细胞周期(traversingstartcontrolpointofmitoticcellcycle)6:cdc2cdc25ccdc6cdc7cdk10cdk2联会复合体形成(synaptonemalcomplexformation)4:sc65stag3sycp1sycp2内SDNA损伤检控点(intra-SDNAdamagecheckpoint)1:nek11确立有丝分裂纺锤体定位(establishmentofmitoticspindlelocaliz-ation)1:espl1确立有丝分裂纺锤体取向(establishmentofmitoticspindleorient-ation)1:pafah1b1染色体凝集(chromosomesegregation)13:espl1psen1psen2pttg1rad21riok3sgol2smc1l1smc1l2srpk1stag1stag2stag3染色体浓缩(chromosomecondensation)1:hils1染色体组织和生物发生(chromosomeorganizationandbiogenesis)8:pttg1pttg3rad50smc1l1smc1l2smc2l1smc5l1smchd1染色体组织和生物发生(见于真核生物)(chromosomeorganizationandbiogenesis(sensuEukaryota)82:abtb2ard1aatrxcbx4cenpachd1chd2chd3chd4cspg6egfh1f0h1fxh2afb1h2afb3h2afvh2afxh2afyh2afy2h2afzh2bfmh2bfsh3f3ah3f3bhist1h1bhist1h1chist1h1dhist1h1ehist1h2abhist1h2achist1h2aehist1h2aghist1h2akhist1h2aps4hist1h2bahist1h2bbhist1h2bchist1h2bdhist1h2bhhist1h2bjhist1h2bkhist1h2blhist1h2bmhist1h2bnhist1h2bohist1h3fhist1h4ghist2h2aahist2h2achist2h2bchist2h2behist2h3chist3h2bbhist3h3hmga1hmga2loc340096loc340549loc347376loc388177loc391405loc391769loc391770loc442461loc653604prm1prm2psen1psen2rad21rad21l1rec8l1rp11-196g18.6rp5-998n21.6smc4l1tnfrsf7tnp1tnp2top3atop3btwist1znf238细胞成熟(cellmaturation)1:il21细胞凋亡(apoptosis)262:acin1ad7c-ntpadora2aadra1aagtr2ahrakt1api5aplp1appapr-2arhgef6atg12atg5avenaxin1axud1bag1bag2bag3bag4bag5baxbbc3bcap29bcap31bcl2l11bcl2l12bfarbirc1birc4birc5birc6birc7bmfbnip1bnip2bnip3lbniplbrec12orf22casp14casp3casp6casp8ap2cd14cd40cd5lcdc2l1cdc2l2cdkn2acgb7ciapin1cias1cideacidebcidecclucropcse1lctnnal1ctnnbl1cycsdad1dapdap3dapk1dapk2dapk3daxxdccddx41dffadffbdhcr24diablodido1dnase1dnase1l3dnase2dock1dpf2e2f1eaf2ebag9edaregln3eif2ak2elmo1elmo2elmo3ep300ern1ern2espl1f2f2rfaf1faimfaim2fasfaslgfastkfis1fksg2flj21901foxo3afxr1gadd45agadd45bgadd45ggas2glrx2gmlgpr65gzmagzmbgzmhhdhipk2hipk3htra2iappier3ihpk3il17il19il1ail1bil24il2raing4itgb2itgb3bpkcnip3kiaa0971kiaa1967lgals12lgals7litafltbrly86maeamageh1magi3map3k5mdm4moap1mrps30mtp18nalp2nckap1ndufa13nfkb1nfkbiangfrngfrap1nme3nme6ntn1p2rx1pak1pawrpax3pdcd1pdcd10pdcd11pdcd2pdcd4pdcd6pdcd6ippdcd7pdcd8pdcl3pde1bphlda1phlpppmlppardppm1fppp1r13bppp1r13lppp1r15aptk2bptpn6ptrh2purapurbrad21raf1rfflripk1ripk3rnf130rnf34rock1rybpscarb1sema6asgksgpl1sh3glb1siah1siah2sirt1sivaslc25a6smndc1spata4spin2sqstm1stk17astk17bstk3stk4sulf1taip-2taok2tbrg4tegttesk2tia1tiaf1tial1tnftnfaip3tnfrsf10atnfrsf10ctnfrsf10dtnfrsf11btnfrsf12atnfrsf14tnfrsf19tnfrsf1atnfrsf1btnfrsf21tnfrsf25tnfrsf6btnfrsf7tnfsf10tnfsf12tnfsf7tnfsf9tp53tp53bp2tp53inp1tp73tp73ltraddtriad3trib3trim35txnl1ube4bunc5aunc5bunc5cunc5dyarszbtb16zdhhc16znf346细胞分裂(celldivision)138:als2cr19anapc1anapc10anapc11anapc2anapc4anapc5anapc7aspmbcar1brrn1bub1bub1bccdc16ccdc5ccna1ccna2ccnb1ccnb2ccnb3ccncccnd1ccnd2ccnd3ccne1ccne2ccnfccng1ccng2ccnkccnt1ccnt2ccrkcdc14acdc16cdc2cdc20cdc23cdc25acdc25bcdc25ccdc2l2cdc2l6cdc40cdc42cdc6cdc7cdca1cdca5cdca8cdk2cdk3cdk4cdk5cdk6cdk7cdk8cenpecenpfcenpjcetn1cetn2cetn3chfrcitcks1bcks2clasp1clasp2cnap1cntrobcspg6dclre1aflj37927ftsj3fzr1hcap-gincenpkatna1katnb1kif11kif23kntc1lats1lats2lig1lig3lig4mad1l1mad2l1mad2l2mapre1mapre2mapre3nedd9nek1nek2nek3nek4nek9nudcpafah1b1papd5pard6apard6bpard6gpolsppp1cappp1cbppp1ccpttg1rad21rcc1rcc2sept1sept10sept11sgol1sgol2sirt2smc1l1smc2l1smc4l1spag5spata5l1sssca1stag1stag2sycp1sycp2tacc1terf1txnl4aube2cwee1zc3hc1znf367zw10细胞溶解(cytolysis)15:c5c6c7c8ac8bc8gc9gzmagzmbgzmhgzmmlyzmmdmmd2prf1细胞生长(cellgrowth)31:arcsrp2ddx5dgkdemp1emp3erbb2ipesr1fgf20fgfr1fgfr2fgfr3fhl1frap1klf6lefty1lefty2loc440836ltbp4mtpnndrg4nop5/nop58notch2p8slc3a2tgfb1tgfb2tgfb3tnnvat1xrn2细胞死亡(celldeath)22:aplp1aptxbnip3cluclul1dbc1eif4g2emp1emp2emp3faf1fosl2il17insnup62parp4psmc5ptger3setxtgfb1tgfb2zak细胞增殖(cellproliferation)253:acheadra1badra1dakr1c3applararegarhgef1bcar1bcat1bhlhb3bin1blzf1bst2btcbub1bub1bbub3c2orf29cbfa2t2cbfa2t3cckbrcd160cd5cd74cdc14acdc16cdc25acdc25ccdc27cdc2l1cdk3cdk4cdk5cdk5r1cdk5rap1cdk5rap3cdk6cdk7cdk9cenpfchgnchrm1chrm3chrm4chrm5cklfcks2clk1col4a3creg1crip1cse1lcsf1csf1rcsrp2ctf1ctnnbip1cul5cxcl1cyr61dab2dctn2dip13bdkc1dlg7dtymke2f1e4f1edd1ednraegfrelnemp1emp2enpepephb4eps15eps8erbb2erbb4erfergevi5fesfgf1fgf2fgf3fgf4fgf5fgf6fgf7fgf8fgf9figffrat2fscn1fth1fzd3gab1gas6gcggfergfi1bgkn1gpc4grngrprhdgfhdgfrp3ifi16ifrd2igf2igfbp4igsf8il15rail1ail1bil2rail5rail6ril8rbil9rilk-2insig1insl4irf2isg20khdrbs1kif2ckitlgklf10krt16lgi1lmo1lrp1lrpap1ly86map3k11mapre1mapre2mas1matkmdkmdm4metmiamifmki67mnat1mplms4a2mt3mtcp1mxd1mycmyt2nab2ndpnpynr6a1nrd1osmosmrpa2g4pcnapdap1pdgfapdgfbpdgfrapemtpes1pgfpim1pim2plk1ppardppbpprdm4prdx1prg4prkd1prlprmt5prok1prok2psphlptchptenptnpurapurbpyyraf1rapgef3rbbp7reg1breg3aretnlbrfprps27runx3s100a6s100bserpinf1sfnshfm3p1sipa1skp2slc29a2sphk2spock1stilsyktacstd2tal1tcf19tcf8tfdp1tgfatgfb1tgfb2tgfb3tgfbithpotnfrsf17tnfsf13btnfsf7tnfsf8tnfsf9tp53tpd52l2tpx2traiptspan1tspan2tspan3tspy1tusc2txlnatxntxndcube2v2usp8vegfvegfbvegfcvti1bwit1zakzfp36l2zmynd11znf259细胞周期(cellcycle)354:ahrals2cr19anapc1anapc10anapc11anapc2anapc4anapc5anapc7ankrd15apcappbp1applaspmatmatraurkaaurkbaurkcaxin1baxbcl10bin1bin3brca1brms1bub1bub1bc10orf46c13orf10c6orf88ccdc16ccdc5ccna1ccna2ccnb1ccnb2ccnb3ccncccnd1ccnd2ccnd3ccne1ccne2ccnfccng1ccng2ccnhccnkccnt1ccnt2ccrkcdc14acdc16cdc2cdc20cdc23cdc25acdc25ccdc2l1cdc2l2cdc42cdc45lcdc5lcdc6cdc7cdc73cdca5cdk2cdk2ap1cdk3cdk4cdk5cdk6cdk7cdk8cdkn1acdkn1bcdkn1ccdkn2acdkn2bcdkn2ccdkn2dcdkn3cdt1cenpecetn1cetn2cgref1cgrrf1chaf1achaf1bchek1chek2chfrcitcks1bcks2clasp1clasp2clspncnap1cntrobcspg6ctcfctcflcul1cul2cul3cul4acul4bcul5cul7cylddbc1dccdclre1addit3ddx11dip13bdlec1dlg7dmbt1dmc1dtymkdusp1e2f1e2f2e2f3e2f4e2f6egfreif2ak2ep300erbb2ipesco1esco2ext1ext2fancd2fhfhitflcnflj37927flj44060fzr1g0s2gadd45agakgas1gas2gmnngps1gps2grlf1gsg2h2afxhcap-ghcfc1hdac4hdac6hic1hmg20bhrasls3hsmpp8htatip2incenping1ing4irf1jag2katna1katnb1khdrbs1kif11kif23klk10kntc1kntc2lats1lats2lig1lig3lig4loc644162loh11cr2alzts1lzts2mad1l1mad2l1mad2l2mapk1mapk12mapk13mapk3mapk4mapk6mapk7mapre1mapre2mapre3mccmcm2mcm3mcm6mcm7mcm8mdc1mis12mki67mlh1mn1mnat1msh2mtss1mutyhnat6nbl1nedd9nek1nek11nek2nek3nek4nek9nf1nf2nipblnme1nme2nolc1nudcpafah1b1papd5parcpard3pard6apard6bpard6gpcafpcnppcoln3pfdn1pin1pinx1pkmyt1pms1pms2pnnpolsppm1dppp1cappp1cbppp1ccptchptenptp4a1pttg1pycardrad17rad21rad50rap1arassf1rb1cc1rbbp4rbl1rbl2rbm22rbm5rcbtb1rcc1rcc2reckrfp2rgs2rhobrif1rint1rp11-291l22.2s100a6sash1sass6sept1sept10sept11sept2sept3sept4sept5sept6sept7sept8sgol1sgol2sh3bp4siah1siah2sirt2smarcb1smc1l1smc1l2smc2l1smc4l1smpd3snf1lkspag5spin2sssca1stag1stag2stag3stim1strn3sufusycp1sycp2tacc1tada2ltaf1taf1lterf1terf2tfdp1tfdp2tlk1tlk2tp53tp53bp2tp73tsc1tsc2tusc2tusc4txnl4atxnl4buba52ube1cube2cuhrf1uhrf2usp16vash1vhlwee1wt1wwoxxrn1zakzc3hc1zmynd11zw10zwintzwintas细胞周期检控点(cellcyclecheckpoint)11:atrbrca1ccne2ccng2cdkn2afancgrad1rb1smc1l1tp53zak细胞周期停滞(cellcyclearrest)68:aif1apbb1apbb2bard1btg4c10orf7cdkn1acdkn1bcdkn1ccdkn2acdkn2bcdkn2ccdkn2dcdkn3cgref1cgrrf1cul1cul2cul3cul4acul5ddit3dhcr24dsteif4g2ern1gadd45agas1gas2gas2l1gas2l2gas2l3gas7hbp1ifnw1il8ing4inhainhbajmykhdrbs1macf1map2k6mapk12mfn2mllt7mphosph1mycnbnnotch2pa2g4pcafpcbp4plagl1pmlppm1gppp1r15appp2r3brassf1sart1sesn1sesn2sesn3tbrg4tp53uhmk1vash1zak雄性减数分裂(malemeiosis)3:hspa2pim2taf1l雄性减数分裂I(malemeiosisI)1:ccna1一维细胞生长(unidimensionalcellgrowth)1:bin3引导细胞凋亡(inductionofapoptosis)92:alox15bapoebadbak1baxbcl10bcl2l11bcl2l13bclaf1bikbnip3bnip3lbokcasp10casp3casp4casp6cd2cias1cidebcideccol4a3dapk2dapk3dccdedddiablodpf1ei24ercc2ercc3ern1ern2fasfaslgfoxo3ahdhrkifna2ifnb1ikbkginhainhbajmylalbalckltamalmap3k10mapk1mx1nalp1nme3notch2nudt2p8pdcd5plagl1plgpmlppp1r13bppp2cappp2r1appp2r1bprkceptenpycards100bsipa1smndc1stk17astk17btia1tial1tlr2tnfrsf10atnfrsf19tnfrsf7tnfrsf9tnfsf10tnfsf12tnfsf14tnfsf8tp53bp2tp73ltpd52l1traddtraf3traipunc13butp11lznf443引导细胞凋亡经死亡域受体(inductionofapoptosisviadeathdom-ainreceptors)10:bidcradddaxxdedddedd2diablofaddil18tnfrsf10atnfrsf10b引导细胞凋亡由胞外信号(inductionofapoptosisbyextracellularsignals)19:adora1baxbtkcasp8ap2cd38cflardapdap3dapk1dpf2fastkmap3k5ndufa13pdcd6prkcaripk3sivatimp3tnfrsf25引导细胞凋亡由激素(inductionofapoptosisbyhormones)3:pthsstr3tp53引导细胞凋亡由细胞内信号(inductionofapoptosisbyintracellularsignals)9:cdkn1acul1cul2cul3cul4acul5hipk2lgals12sart1引导细胞凋亡由氧化压力(inductionofapoptosisbyoxidativestress)2:prodhrnf7有丝分裂(mitosis)98:akap8anapc1anapc11anapc2anapc7aspmaurkabrrn1bub1bub1bbub3ccdc16ccdc5ccna1ccna2ccnb1ccnb2ccnfccng1ccng2ccnkcdc2cdc20cdc25acdc25bcdc2l1cdc2l2cdc6cdca5cdk2cdk3cenpfcetn1cetn2cetn3chfrcitclasp1clasp2cnap1coro1adclre1adctn1dctn2dctn3eml4fgf4flj37927fzr1hcap-ghgfincenpkatna1katnb1kif22kif23kif2ckntc1lats1lats2mad2l1mad2l2mapre1mapre2mapre3mis12nedd9nek1nek3nek4nek9nolc1nudcpafah1b1papd5pbkplk1polsppp5cpttg1rad21rcc2sgol1sirt2smc2l1spag5sssca1stag1stag2sugt1tardbptpx2ttntxnl4atxnl4bube2cwee1zc3hc1有丝分裂G2检控点(mitoticG2checkpoint)