开幕式领导致辞三篇

1、我国结核病的疫情状况 ?WHO 93年宣布“全球结核病紧急状态”，98年又重申遏制结核病的行动刻不容缓。 ?全球现有结核病人2000万，其中95在发展中国家，每年还会新发生800-1000万肺结核病，其中75的病人年龄在1550岁。如不控制，今后10年还将有9000万人发病。 ?中国是全球22个结核病高负担国家之一，结核病人数位居世界第二位，仅次于印度. ?据调查全国三分之一的人口已感染了结核菌；受感染人数超过4亿,受结核感染人群中有10的人发生结核病 1 tuberculosis ?factor of tuberculosis incidence rising ： HIV spread. T

2、B strain occur drug resistance . fluid population increasing. Management TB patient not perfect、prevention and cure not efficiency. Poverty、population increasing. 2 etiology ?Mycobacterium 、 Acid fastness、G+、aerobe。 ?Growth torpidity , culture need 4-6 weeks. ?Typing : human type 、 bovine type 、 Bir

3、d type、mouse type 、 main human type。 ?way of infection：respiration tract、digestive track、skin or placenta. 3 Epidemiology ?1 infection sources：open pulmonary tuberculosis ?2 route of transmission: by respiration way or digestion tract. ?3 susceptible population 4 Epidemiology ?The factors lead Child

4、ren ill with TB Contact TB amounts and toxicity. power of resistance . hereditary factor . 5 pathogenesy bacterial number、toxicity、immunization condition ?Cell-mediated immune reaction:macrophage swallow TBantigen presentation Th and macrophageIL12CD+4TH1-IF-to promote mononuclear cell; to gather、ac

5、tivation、proliferation and differentiationto produce alexin and oxidase 、 digestive enzymeto kill TB 6 pathogenesy ?IF-reinforcement CD+8 、NK cells activity to phagocytosis TB. meanwhile to lead histoclasia ?delayed allergy : T cell media，macrophage to be effector cell，to kill reinfection TB and cau

6、se cheesy necrosis or hole formation ?After Infection TB : primary disease（5%），Secondary disease （5%）, not to fall ill all live(90%) 7 diagnose ?Objective to discover focal 。 Definite disease character、size whether or not deliver bacterium。 8 diagnose ?1 history TB toxic symptom to contact TB patien

7、t BCG vaccination acute infection:measles，pertussis Supersensitivity ?erythema nodosum、exanthematous conjunctivitis。 9 diagnose ?2 ：OT test agent：1/2000 or 1/10000 PPD dose：0.1ML（OT 5U）（or 1U）。 position：left forearm palmaris below 1/3 Infuse intracutaneous form 6-10mm hillock。 4872hr observation rea

8、ction。 10 diagnosis ?reaction 5mm(-) 5mm(+) 10-19mm(+) 20mm(+) Super reaction :induration、vesic 、 local ulceration (+)。 11 diagnosis ?significance positive reaction ?After BCG vaccination ?Older children positive reaction indicate to be ever infected with TB before。 ?Infant never BCG vaccination indicate new infectio