碱化利多卡因联合肝素膀胱灌注治疗膀胱疼痛综合征间质性膀课件

1、 国内尚无明确统计资料。国内尚无明确统计资料。 nNIDDK于于 1987年制定了的诊断标准年制定了的诊断标准 n 同时满足以下两个条件同时满足以下两个条件 1膀胱区疼痛或尿频尿急膀胱区疼痛或尿频尿急 2典型的典型的Hunners溃疡，或肾丝球状出血点（溃疡，或肾丝球状出血点（10个出血点个出血点/每象每象 限限, 在在3个象限以上，个象限以上，麻醉麻醉下水扩张时）下水扩张时） 治治 疗疗 The OLeary-Sant IC Indices4 Problem Index During the past month, how much has each of the following bee

2、n a problem for you: Q1: Frequent urination during the day? Q2: Getting up at night to urinate? Q3: Need to urinate with little warning? Q4: Burning, pain, discomfort or pressure in your bladder? _ no problem = 0 _ very small problem = 1 _ small problem = 2 _ medium problem = 3 _ big problem = 4 Tot

3、al score: _/16 Symptom Index During the past month, how much has each of the following been a problem for you: Q1: Felt a strong need to urinate with little or no warning? _ not at all = 0 _ less than 1 time in 5 = 1 _ less than half the time = 2 _ about half the time = 3 _ more than half the time =

4、 4 _ almost always = 5 Q2: Urinate less than 2 hours after urinating? _ not at all = 0 _ less than 1 time in 5 = 1 _ less than half the time = 2 _ about half the time = 3 _ more than half the time = 4 _ almost always = 5 Q3: Get up at night to urinate? _ not at all = 0 _ 1 time = 1 _ 2 times = 2 _ 3

5、 times = 3 _ 4 times = 4 _ 5 times = 5 Q4: Experienced pain or burning in your bladder? _ not at all = 0 _ a few times = 1 _ fairly often = 2 _ almost always = 3 _ always = 4 Total score: _/19 215215例患者得到完全随访，随访时间例患者得到完全随访，随访时间318318个月，平均个月，平均 9.49.4个月。根据个月。根据OLeary-Sant ICOLeary-Sant IC问卷表数据比较，治疗问卷

6、表数据比较，治疗1 1 个月后个月后ICSIICSI 平均值降为平均值降为(10.3(10.34.1)4.1)分，分，ICPIICPI平均值降为平均值降为 (6.6(6.62.8)2.8)分；治疗分；治疗3 3个月后个月后 ICSIICSI 平均值降为平均值降为(6.5(6.53.6)3.6) 分，分，ICPIICPI平均值降为平均值降为(3.2(3.22.0)2.0)分。分。 治疗前后治疗前后OLeary-Sant评分比较评分比较 n 治疗治疗1 1、3 3个月后下腹酸胀个月后下腹酸胀/ /疼痛的改善率分别为疼痛的改善率分别为29.8%29.8% 和和71.3%71.3%，夜尿增多的改善率分别为，夜尿增多的改善率分别为21.6%21.6%和和65.3%65.3%，尿频，尿频 尿急的改善相对不明显，分别为尿急的改善相对不明显，分别为9.6 %9.6 %和和22.8%22.8%。 治疗前后治疗前后IC/PBS各临床症状改善情况各临床症状