急性胃炎课件

1、急性胃炎1 第四章第四章 胃炎胃炎 GASTRITIS 急性胃炎2 急性胃炎3 急性胃炎4 急性胃炎5 Gastritis represents a nonspecific inflammation of the stomach.Clinically,the three most common and important causes of gastritis are infection of nonsteroidal anti- inflammatory drugs(NSAIDs),and stress- related mucosal changes. (5p334) 急性胃炎6 急性胃炎

2、7 急性胃炎8 急性胃炎9 急性胃炎10 急性胃炎11 急性胃炎12 急性胃炎13 Clinical features Nausea and vomiting are the most likely presenting symptoms,together with indigestion. Acute gastrointestinal if gastritis is severe. Asymptomatic. (2p109) 急性胃炎14 急性胃炎15 Diagnosis and investigation Often made on clinical grounds, e.g. Histo

3、ry of non-steroidal anti-inflammatory drugs,heavy alcohol consumption, etc. Endoscopy appearance can vary from superficial erosions to haemorrhage secondary to acute ulceration . (2p109) 急性胃炎16 急性胃炎17 急性胃炎18 Superficial gastritis) ( (The inflammatory cell are confined to the pit rigion) (There is va

4、riable gland loss,which is often accompanied by intestinal metaplasia. ) 急性胃炎19 (Intestinal metaplasia)： 急性胃炎20 (dysplasia)： 急性胃炎21 急性胃炎22 急性胃炎23 急性胃炎24 Helicobacter pylori H.pylori is a gram-negative, curved, flagellated rod found only in gastric epithelium or in gastric metaplastic epithelium. H.p

5、ylori is a noninvasive organism that colonizes the mucus layer overlying gastric epithelium. Factors important in the organisms ability to colonize the stomach to adhere to the mucus layer, and production of urease. Urease increases juxtamucosal pH, creating a more hospitable microclimate than that

6、of the acidic stomach. (5p334) 急性胃炎25 急性胃炎26 急性胃炎27 急性胃炎28 急性胃炎29 急性胃炎30 Clinic features Most cases are asymptomatic. Symptoms are similar to those of acute gastritis, but occurring over a period of time. Pernicious anaemia due to loss of intrinsic factor secretion for vitamin B12 absorption occurs

7、in patients with autoimmune gastritis. 急性胃炎31 胃液分析胃液分析 血清学检查血清学检查 胃镜检查及活检胃镜检查及活检 幽门螺杆菌检查幽门螺杆菌检查 X线检查线检查 维生素维生素B12吸收检查吸收检查 急性胃炎32 急性胃炎33 急性胃炎34 急性胃炎35 急性胃炎36 急性胃炎37 急性胃炎38 急性胃炎39 急性胃炎40 急性胃炎41 急性胃炎42 急性胃炎43 急性胃炎44 急性胃炎45 急性胃炎46 急性胃炎47 幽门螺杆菌感染的胃炎治疗幽门螺杆菌感染的胃炎治疗 无幽门螺杆菌的胃炎治疗无幽门螺杆菌的胃炎治疗 急性胃炎48 急性胃炎49 急性胃炎50 急性胃炎51 急性胃