味精安全问题PPT课件

1、12345skeletal stunting骨萎缩骨萎缩marked obesity明显肥胖明显肥胖sterility 不育不育hypothalamic lesions下丘脑损伤下丘脑损伤msg injected注射味精后注射味精后67891011adult males (80 kg) quickly ingested msg, 12.7 g (150 mg/kg) in solution.成年男子 （体重约80公斤）能很快吸收溶液中12.7g（约150毫克每公斤）的味精time (minutes)060120180240plasma glu (nmol/ml)1002003004005001

2、2arrows = meal or snack 箭头代表摄取的食物或点心meals: 0745, 1215, 1800 h 饮食时间：0745，1215，1800data are means sem(n = 10)数据：均值标准差black circle: no msg黑圈表示不含味精white circle: msg.白圈表示含有味精13time (minutes)060120180240plasma prolactin (ng/ml)510152025trh placebomsgprotein meal14stegink ld et al am j obstet gynecol 122:

3、70-78 (1975)monkey study.猴子实验猴子实验highest dose (400 mg/kg iv, open circles) produced plasma glu 70-times normal.battaglia fc. j nutrition 130: 974s-977s (2000)1516lactating women ingested 100 mg/kg msg in capsules with water, and milk samples were taken at the indicated times thereafter. from: baker

4、gl et al., factors influencing dicarboxylic amino acid content of human milk. in: , filer lj et al., ed. new york, raven press, 1979 , pp. 111-123.哺乳期女性加水摄入 100 mg/kg 的胶囊，对其后特定时间的母乳样品进行检验表明：这一剂量使得血液谷氨酸浓度在这一剂量使得血液谷氨酸浓度在30-45分钟内从分钟内从 from: baker gl et al., factors influencing dicarboxylic amino acid c

5、ontent of human milk. in: , filer lj et al., ed. new york, raven press, 1979 , pp. 111-123.影响人体母乳二氨基酸浓度的因素谷氨酸：生物化学和生理学进展171819202122232425geha rs et al., j allergy clin immunol 106:973-80, 200026geha rs et al., j allergy clin immunol 106:973-80, 200027geha rs et al., j allergy clin immunol 106:973-8

6、0, 200028geha rs et al., j allergy clin immunol 106:973-80, 20002930geha rs et al., j allergy clin immunol 106:973-80, 200031geha rs et al., j allergy clin immunol 106:973-80, 200032geha rs et al., j allergy clin immunol 106:973-80, 200033geha rs et al., j allergy clin immunol 106:973-80, 2000conclu

7、sion: using criteria established by the 1995 faseb panel, none of the individuals who claimed a sensitivity to msg actually showed this sensitivity when tested under blinded conditions.结论：根据1995年美国实验生物学联合会（faseb）制定的标准，对那些声称味精过敏的个体进行双盲试验表明他们未表现出敏感性。34stevenson dd. monosodium glutamate and asthma. j n

8、utr 130: 1067s-1073s, 2000味精和哮喘 2000年 营养学杂志.35simon ra. additive-induced urticaria: experience with monosodium glutamate (msg).j nutr 130: 1063s-1066s, 2000.36 bazzano g, delia ja, olson re science 169: 1208-1209, 1970.adult human subjects ingested a chemically-de-fined diet supplying all of the essential amino acids in optimum amounts, plus glutamic acid as the sole source of non-essential nitrogen, for 14-42 days. no subjects developed the chinese restaurant syndrome. no changes in weight, irr