多发性骨髓瘤化疗方案

1、化疗方案骨髓瘤力杀药物剂量用法ABVD每28k周期阿霉素225mg/mivd1,15210mg/mivd1,15长春碱6mg/mivd1,15达卡巴嗪2375mg/mivd1,15BACOP（*为加强方案）阿霉素25mg/m(*40mg/n2)或EPIivd1,8每28k周期22、40mg/m(*50mg/m)环磷酰胺2650mg/mivd1,8长春荆1碱2mivd1,8泼尼松240-60mg/mpod15-2810mg/m2ivd15,22BEACOPP（*为加强方案）阿霉素25mg/m(*35mg/m)ivd1每21k周期环磷酰胺650mg/r2i(*1250mg/n2)ivd1依托泊甘1

2、00mg/m(*200mg/n2)ivd1-3长春荆1碱m(max2mg/m)ivd8甲基平肌2100mg/mpod1-7泼尼松240mg/mpod1-14210mg/mivd8dex-DEAM卡莫司汀260mg/mivd2美法仑220mg/mivd3依托泊甘2200mg/miv,Q12hd4-7阿糖胞苜2100mg/miv,Q12hd4-7地塞米松8mgpo,tidd1-10mini-DEAM卡莫司汀260mg/mivd1美法仑230mg/m(max50mgivd5依托泊甘75mg/mivd2-5阿糖胞苜2100mg/miv,Q12hd2-5CHOP14天或21阿霉素50mg/m(或EPI8

3、0mg/m2)ivd1周期环磷酰胺2750mg/mivd1长春荆1碱2mivd1泼尼松100mgpod1-5CHOP-E每21k周期阿霉素50mg/m(或EPI80mg/m2)ivd1环磷酰胺2750mg/mivd1长春荆碱2mivd1依托泊甘2100mg/mivd1-3泼尼松100mgPod1-5CHOP-L-ASP每21天-周期阿霉素50mg/m(或EPI80mg/m2)ivd1环磷酰胺2750mg/mivd1长春荆碱2m(max2mgivd1泼尼松100mgpod1-5左旋门冬6000U/ivd1,3,7,9,酰胺酶11CEOP每21天一周期环磷酰胺2500mg/miv依托泊甘2mivd

4、1长春荆碱2mgivd1泼尼松75mg/mpod1COPd1-5每14-21k周环磷酰胺2750mg/miv期长春荆碱2m(max2mgivd1泼尼松100mgpod1,8COPPd1-5每28天"周期环磷酰胺600-800mgiv长春荆碱2m(max2mgivd1,8内卡巴肥2100mg/mpod1,8泼尼松240mg/mpod1-14CVPd1-14每21天一周期环磷酰胺2400mg/miv长春荆碱(max2mgivd1-5泼尼松100mgpod1DDP-VP-16d1-5每21天-周期顺柏230mg/mivd1-3(水依托泊甘240-50mg/miv化）DHAPd5-10每14

5、-21k周顺柏2100mg/miv期阿糖胞苜_22g/miv,Q12hd1地塞米松40mgivd2DICEd1-4每21天一周期异环磷酰1000mg/rniv胺d1-4顺柏225mg/miv依托泊甘260mg/mivd1-4地塞米松26-9mg/mpod1-4EPOCHd1-10每21天-周期阿霉素210mg/miv（连续96hd1-4依托泊甘50mg/n2iv（连续96h)d1-4长春新碱miv（连续96h)d1-4环磷酰胺750mg/rniv泼尼松60mg/mPod5EPOCHd1-5每21天同期依托泊甘60mg/miv2顺柏25mg/miv(连续d1-496h)d1-4甲泼尼龙500mg

6、/miv阿糖胞苜2g/mivd1-4FCd5每28天一周期氟达拉滨25-30mg/miv环磷酰胺250-300mg/Riivd1-3FCMd1-3每28天同期弗1辽拉浜25mg/miv米托恿酿6-8mg/mivd1-32环磷酰月女200mg/mivd1FCMd1-3每28天同期弗1辽拉浜25mg/miv米托恿酿10mg/mivd1-3地塞米松20mgiv/pod1GDPd1-5每21天一周期吉西他滨1000mg/miv顺柏75mg/mivd1,8地塞米松40mgivd1GemOxd1-4吉西他滨1000mg/miv奥沙利柏100mg/mivd1ICEd1依托泊甘100mg/miv异环磷酰500

7、0mg/miv(24hd1-3胺输注）卡伯按AUC=5max800mgivd2IVEd2母21天一周期表阿毒素50mg/miv异环磷酰3000mg/miv(22h)d1胺d1-3依托泊甘200mg/miv(>2h)MACOP-Bd1-3母12周重复一阿毒素50mg/miv周期wk1,3,5,7环磷酰胺2350mg/miv,9.11wk1,3,5,7长春新碱2m(max2mgiv,9.11wk2,4,6,8210mg/miv,10,12泼尼松75mg/dpowk4,8,12wk1-11后逐渐减量MIMEwk2,6,10Methy-2500mg/mivguazoned1异环磷酰1000mg/

8、rniv胺d1-5依托泊甘2100mg/miv甲氨蝶吟230mg/mivd1-3MOEPd3每21周期米托恩酿10mgiv长春新碱2m(max2mgivd1-3依托泊甘100mgivd1泼尼松60mgpod1-5MOPPd1-5每28k周期氮扑6mg/miv长春新碱2mivd1,8内卡巴肥2100mg/mpod1,8泼尼松240mg/mpod1-14SMILEd1-14每28k周期甲氨蝶吟2g/m2iv异环磷酰1500mg/mivd1胺d2-4依托泊甘2100mg/miv地塞米松240mg/mivd2-4L-ASP6000U/mivd2-4d8,10,12,HD-MTX14,16,18,甲氨蝶

9、吟1-3giv(12h)20HD-AraC阿糖胞苜3g/m2iv,Q12hd1ABCM阿霉素230mg/mivd1-3(6)卡莫司汀230mg/miv环磷酰胺2100mg/mpod1美法仑6mg/mpod1DCEPd22-25地塞米松40mg/dIv/pod22-2544441111ddddk4持：1伟1111d勿一dddd持持持。持持持aj)1/1/1/11/1/1/一IVIVIVIVI30IVIVIVIVpod1-4pod1-4ivivd1-4ivdipodidiivd1-7,8-14ivivd1-4ivd1-4d1-5ivd5ivpod1-4d1-4d1-4,po9-12,17-2iv/

10、po0d1-21pod1-4,9-12,17-20iv每月wks1-3powks2-5,13iv-16ivd1-21pod1环磷酰胺2400mg/m依托泊甘240mg/m顺柏210mg/mDT-PACE地塞米松40mg/d沙利度胺400mg/d阿霉素210mg/m顺柏210mg/m环磷酰胺2400mg/m依托泊甘240mg/mMP每4-6周一周期美法仑210mg/m泼尼松250mg/mM2美法仑8mg/m卡莫司汀220mg/m环磷酰胺2400mg/m长春新碱2m泼尼松40mg/nm,20mg/iPEDA顺柏220mg/m依托泊甘2100mg/m地塞米松40mg/d阿糖胞苜1g/m2VAD长春新

11、碱2m阿霉素9mg/m地塞米松40mgLD雷利度胺25mg/d地塞米松40mg/dLR雷利度胺25mg/d利妥昔单2375mg/m抗L+DVD雷利度胺10mg/d脂质体阿240mg/m霉素长春新碱2mg地塞米松40mg/dL+MP雷利度胺5-10mg/dpod1美法仑或mpod1-4泼尼松5,10,15,20mg/dpoCTDd1-21沙利度胺2mpod1-4环磷酰胺50,100,150,200mg/dpod1-4地塞米松poMPTd1-28沙利度胺pod1-21美法仑pod1-4,15-2泼尼松po1TD沙利度胺pod1-28地塞米松pod1-7d1-7pod1-28d1-4,9-12TDD,17-20（奇沙利度胺po数周期）脂质体阿ivd1-4（偶数霉素周期）地塞米松pod1-28TPd1沙利度胺po泼尼松pod1-4,9-12VD,17-20硼替佐米iv地塞米松ivQdQodd1,4,8,11d1-4,9-12VMP,17-20（奇硼替佐米iv数周期）d1-4（偶数美法仑iv周期）泼尼松poPDAd1,4,8,11硼替佐米iv,22,25,29阿霉素iv,32地塞米松