Limonin-Limonoic-acid-3-19-16-17-dilactone-DataSheet-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemELimoninCat. No.: HY-17411CAS No.: 1180-71-8Synonyms: Limonoic acid 3,19:16,17 dilactone分式: CHO分量: 470.51作靶点: HIV作通路: Anti-infection储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO : 110 mg/mL

2、(233.79 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.1254 mL 10.6268 mL 21.2535 mL5 mM 0.4251 mL 2.1254 mL 4.2507 mL10 mM 0.2125 mL 1.0627 mL 2.1254 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。BIOLOGICAL ACTIVITY物活性 Limonin为柑橘类果中富含的三萜类化合物，具有抗病毒和抗肿

3、瘤活性。REFERENCES1/2 Master of Small Molecules 您边的抑制剂师www.MedChemE1. Han YL, Yu HL, Li D, et al. Inhibitory effects of limonin on six human cytochrome P450 enzymes and P-glycoprotein in vitro. Toxicol InVitro. 2011 Dec;25(8):1828-33.2. Kotamballi N. Chidambara Murthy, Jayaprakasha, Vinod Kumar, et al.

4、Citrus Limonin and Its Glucoside Inhibit Colon AdenocarcinomaCell Proliferation through Apoptosis. J. Agric. Food Chem., 2011, 59 (6):2314-2323.3. Mahmoud Zaki El-Readi, Dalia Hamdana, Nawal Farrag, et al. Inhibition of P-glycoprotein activity by limonin and other secondarymetabolites from Citrus sp

5、ecies in human colon and leukaemia cell lines. European Journal of Pharmacology. 2010,626 (2-3): 139-145.4. Battinelli L, Mengoni F, Lichtner M, et al. Effect of limonin and nomilin on HIV-1 replication on infected human mononuclear cells. PlantaMed. 2003 Oct;69(10):910-3.5. Tanaka T, Kohno H, Tsukio Y, et al. Citrus limonoids obacunone and limonin inhibit azoxymethane-induced colon carcinogenesis in rats.Biofactors. 2000;13(1-4):213-8.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-37