BM212 - Bacterial 抑制剂 - 生命科学试剂 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEBM212Cat. No.: HY-100725CAS No.: 146204-42-4分式: CHClN分量: 414.37作靶点: Bacterial作通路: Anti-infection储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 Ethanol : 5.56 mg/mL (13.42 mM; Need ultrasonic)DMSO

2、 : 40% PEG300 5% Tween-80 45% salineSolubility: 0.56 mg/mL (1.35 mM); Clear solution2. 请依序添加每种溶剂： 10% EtOH 90% (20% SBE-CD in saline)Solubility: 0.56 mg/mL (1.35 mM); Clear solution3. 请依序添加每种溶剂： 10% EtOH 90% corn oil1/2 Master of Small Molecules 您边的抑制剂师www.MedChemESolubility: 0.56 mg/mL (1.35 mM); C

3、lear solutionBIOLOGICAL ACTIVITY物活性 发挥杀菌活性与细胞内细菌驻留,完全抑制胞内分枝杆菌。REFERENCES1. Poce G et al. Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection. PLoS One.2013;8(2)2. Deidda D et al. Bactericidal activities of the pyrrole derivative BM212 against multid

4、rug-resistant and intramacrophagic Mycobacteriumtuberculosis strains. Antimicrob Agents Chemother. 1998 Nov;42(11):3035-7.3. Deidda D et al. Bactericidal activities of the pyrrole derivative BM212 against multidrug-resistant and intramacrophagic Mycobacteriumtuberculosis strains.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: 0