Pulchinenoside-C-Anemoside-B4-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEPulchinenoside CCat. No.: HY-N0205CAS No.: 129741-57-7Synonyms: Anemoside B4分式: CHO分量: 1221.38作靶点: Others作通路: Others储存式: 4C, protect from light* In solvent : -80C, 6 months; -20C, 1 month (protect fromlight)溶解性数据体外实验 DMSO : 125

2、mg/mL (102.34 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 0.8187 mL 4.0937 mL 8.1875 mL5 mM 0.1637 mL 0.8187 mL 1.6375 mL10 mM 0.0819 mL 0.4094 mL 0.8187 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验 请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄清的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液，建议您

3、现现配，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.08 mg/mL (1.70 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.08 mg/mL (1.70 mM); Clear solution3. 请依序添加每种溶剂： 10% DMSO 90% corn oilSolubilit

4、y: 2.08 mg/mL (1.70 mM); Clear solution1/2 Master of Small Molecules 您边的抑制剂师www.MedChemEBIOLOGICAL ACTIVITY物活性 Pulchinenoside C (Anemoside B4)个天然的头翁皂苷B4，有很多物效应，例如抗肿瘤，神经保护，抗管成等活性。体外研究 Pulchinenoside C (Anemoside B4) can inhibit the secretion of IL-10; SSA, SSD and PNS up-regulated IL-2expression 1. P

5、ulchinenoside C (Anemoside B4), with IC50 value more than 390 ug/mL. Anemoside B4inhibits cell proliferation 2. Pulchinenoside C (Anemoside B4) can significantly suppress the secretion of theinflammatory factor E-selectin by endothelial cells 3.REFERENCES1. Hu Y et al. Role of Chinese herbal medicin

6、al ingredients in secretion of cytokines by PCV2-induced endothelial cells. J Immunotoxicol.2016;13(2):141-7.2. Liu M et al. Cytotoxicity of the compounds isolated from Pulsatilla chinensis saponins and apoptosis induced by 23-hydroxybetulinicacid. Pharm Biol. 2015 Jan;53(1):1-9.3. Hu Y et al. Chinese herbal medicinal ingredients inhibit secretion of IL-6, IL-8, E-selectin and TXB2 in LPS-induced rat intestinalmicrovascular endothelial cells. Immunopharmacol Immunotoxicol. 2009;31(4):550-5.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use on