Pyrroloquinoline-quinone-disodium-salt-PQQ-disodium-salt-DataSheet-生命科学试剂-MedChemExpress

Hotline:400-820-3792Inhibitors•ScreeningLibraries•Proteinswww.MedChemEPyrroloquinolinequinonedisodiumsaltCat.No.:HY-100196ACASNo.:122628-50-6Synonyms:PQQdisodiumsalt;Methoxatindisodiumsalt分⼦式:C₁₄H₄N₂Na₂O₈分⼦量:374.17作⽤靶点:EndogenousMetabolite作⽤通路:MetabolicEnzyme/Protease储存⽅式:4°C,sealedstorage,awayfrommoisture*Insolvent:-80°C,6months;-20°C,1month(sealed

storage,awayfrommoisture)溶解性数据体外实验H2O:1.25mg/mL(3.34mM;Needultrasonic)MassSolvent1mg5mg10mgConcentration制备储备液1mM2.6726mL13.3629mL26.7258mL5mM---------10mM---------请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造成的产品失效。储备液的保存⽅式和期限：-80°C,6months;-20°C,1month(sealedstorage,awayfrommoisture)。-80°C储存时，请在6个⽉内使⽤，-20°C储存时，请在1个⽉内使⽤。体内实验请根据您的实验动物和给药⽅式选择适当的溶解⽅案。以下溶解⽅案都请先按照InVitro⽅式配制澄的储备液，再依次添加助溶剂：(为保证实验结果的可靠性，澄的储备液可以根据储存条件，适当保存；体内实验的⼯作液，建议您现⽤现配，当天使⽤；以下溶剂前显⽰的百分⽐指该溶剂在您配制终溶液中的体积占⽐；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的⽅式助溶)1.请依序添加每种溶剂：0.5%CMC-Na/salinewaterSolubility:5mg/mL(13.36mM);Suspendedsolution;Needultrasonic1/2MasterofBioactiveMolecules—您⾝边的抑制剂⼤师www.MedChemEBIOLOGICALACTIVITY⽣物活性Pyrroloquinolinequinonedisodiumsalt氧化还原辅助因⼦，⼀种离⼦型氧化还原循环原醌。Pyrroloquinolinequinonedisodiumsalt最初从嗜甲细的培养物中分离的，也存在于哺乳动物的组织。Pyrroloquinolinequinonedisodiumsalt哺乳动物的必需营养素，对免疫功能很重。IC50&TargetHumanEndogenousMetabolite体外研究MousepupsborntoandnursingfromPyrroloquinolinequinonedisodiumsalt-depriveddamshaveacompromisedimmuneresponseaswellasalopecia,ahunchedposture,andasusceptibilitytoaorticaneurysms[2].REFERENCES[1].MoogRS,etal.Evidenceformethoxatin(pyrroloquinolinequinone)asthecofactorinbovineplasmaamineoxidasefromresonanceRamanspectroscopy.ProcNatlAcadSciUSA.1986Nov;83(22):8435-9.[2].BishopA,etal.Methoxatin(PQQ)inguinea-pigneutrophils.FreeRadicBiolMed.1994Oct;17(4):311-20.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-8