2023ChatGPT医疗行业应用白皮书

ChatGPT

Application inHealthcare

Report2023年9月101

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GPT24数据来源：OpenAI官网（

/

）ChatGPTOpenAILLMGPTChatGPT/2020.6.11GPT-3⚫

GPT-3⚫2022.11.30ChatGPT/GPT-3.5⚫

ChatGPT GPT-3.5⚫2023.3.14GPT-4⚫/⚫⚫ChatGPTChatGPT5数据来源：行业公开信息整理。••••2023ChatGPT6数据来源：案例采用ChatGPT（GPT-4模型）对话。7数据来源：案例采用ChatGPT（GPT-4模型）对话。8数据来源：案例采用ChatGPT（GPT-4模型）对话。9数据来源：行业公开信息整理。ChatGPTPaLMAIPubMedGPT

Med-AIAIAI20222022OpenAIChatGPT10PubMedGPT数据来源：

/stanford-crfm/BioMedLM•••••••PubMedGPT BioMedLMStanford MosaicML•••••••••11数据来源：谷歌，https://sites.research.google/med-palm/50.36067.2

85.4 9080706050403020100PubMedGPTMed-PaLMMed-PaLM2AIMed-PaLMMed-PaLM267.285.4PubMedGPTMed-PaLMPubMedGPTvs

Med-PaLM12数据来源：谷歌，https://sites.research.google/med-palm/13Dragon数据来源：/michiyasunaga/dragon•••••••DRAGONDRAGON(DeepBidirectionalLanguage-KnowledgeGraph

Pretraining)Stanford

University-•••••••••JohnsNvidiaHippocraticMedicareHopkins Stanford GoogleAIGeneral

CatalystHippocratic”14数据来源：官网（）70.9%76.2%65.3%80.3%48.5%71.4%91.1%88.6%71.0%92.3%72.7%83.7%100%90%80%70%60%50%40%30%20%10%0%GPT-4Hippocratic

AI•••••HippocraticGPT-415数据来源：官网（）16数据来源：行业公开信息整理。•••QALLMQAQA17数据来源：/jind11/MedQA••Question:A57-year-oldmanpresentstohisprimarycarephysicianwitha2-monthhistoryofrightupperandlowerextremityweakness.Henoticedtheweaknesswhenhestartedfallingfarmorefrequentlywhilerunningerrands.Sincethen,hehashadincreasingdifficultywithwalkingandliftingobjects.Hispastmedicalhistoryissignificantonlyforwell-controlledhypertension,buthesaysthatsomemembersofhisfamilyhave

hadmusculoskeletalproblems.HisrightupperextremityshowsforearmatrophyanddepressedreflexeswhilehisrightlowerextremityishypertonicwithapositiveBabinskisign.Whichofthefollowingismostlikelyassociatedwiththecauseofthispatients

symptoms?Options:A:

HLA-B8

haplotype,

B:

HLA-DR2

haplotype,

C:

Mutation

inSOD1,D:MutationinSMN1,E:Viral

infection（答案为A）••••••••MedQA-USMLE•18数据来源：https://huggingface.co/datasets/pubmed_qa••••••••••••Question:Dopreoperativestatinsreduceatrialfibrillationafter

coronaryarterybypass

grafting?Context:(Objective)Recentstudieshavedemonstratedthatstatins

havepleiotropiceffects,includinganti-inflammatoryeffectsandatrialfibrillation(AF)preventiveeffects

[...](Methods)221patientsunderwentCABGinourhospitalfrom2004to2007.14patientswithpreoperativeAFand4patientswithconcomitantvalvesurgery

[...](Results)TheoverallincidenceofpostoperativeAFwas

26%.PostoperativeAFwassignificantlylowerintheStatin

groupcomparedwiththeNon-statingroup(16%versus33%,

p=0.005).[...]Long

Answer:(Conclusion)

Our

study

indicated

that

preoperative

statin

therapyseemstoreduceAFdevelopmentafter

CABG.Answer:

yesPubMedQAQA19•Question：Chronicurethralobstructionduetobenignprismatichyperplasiacanleadtothefollowingchangeinkidney

parenchyma?Options:HyperplasiaHyperophyAtrophyDysplasiaCorrectAnswer:c)

AtrophyExplanation:Chronicurethralobstructionbecauseofurinarycalculi,

prostatichyperophy,tumors,normal

pregnancy[…]Subject:

AnatomyTopic:Urinary

tract••••••••••MedMCQA Subject数据来源：https://huggingface.co/datasets/medmcqaTopic20数据来源：/dataset/frenchmedmcqa•••••••••Question：Cocherla(les)proposition(s)exacte(s):Le

métronidazoleOptions:Estundérivédu

pyrazolePeutinduireuneffet

antabusePeutêtreadministréparvoieparentérale

intraveineusePeutêtreutilisédanscertainesparasitoses

àprotozoairesEstinefficacedanslesinfectionsàgermes

anaérobiesCorrect

Answer:Peutinduireuneffet

antabusePeutêtreadministréparvoieparentérale

intraveineusePeutêtreutilisédanscertainesparasitoses

àprotozoairesFrenchMedMCQAAI•22注：*

表示潜在的应用场景（暂无落地案例覆盖）ChatGPTChatGPT23数据来源：

kahun公司官网（

）24注：案例展示为测试版软件演示，kahun公司尚未披露产品应用后的实际数据。•ChatGPT•••••25数据来源：公司官网（

）26数据来源：官网（）27数据来源：截图来自软件试用，指标数据来自官网（）/2350%Nabla

Copilot28数据来源：官网（

）29数据来源：官网（

），

DocsGPT网站（

www.DocsGPT.com）30数据来源：DocsGPT网站（

www.DocsGPT.com）GPTDocsGPT31数据来源：官网（）33••34数据来源：官网（）、ChatGPT

Plugin

Store35数据来源：官网（）、ChatGPT

Plugin

Store36数据来源：

Clinical

Trial

Radar（ChatGPT插件）37数据来源：

Clinical

Trial

Radar（ChatGPT插件）COVID-1938数据来源：

Clinical

Trial

Radar（ChatGPT插件）39数据来源：官网（www.

www.ferma.ai）生命科学网站、新闻，官方发布FDA

Labeling（药品和医疗器械标签上的信息和要求的规定）美国证券交易委员会报告（SEC

Calls）财报电话会议（Earning

Calls）PubMed医学文献数据库Clinical

Trial数据库1 行业新闻2 药审监管3 财经信息4 医学数据信息源回答质