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1MainSymptomsandSignsofCommonCardiovascularDiseases1循环系统常见症状体征英5/8/2024Outline2010ClinicalDiagnosticsValvularHeartDisease
MitralStenosis (MS)
MitralRegurgitation/Insufficiency(MR/MI)
AorticStenosis (AS)
AorticRegurgitation/Insufficiency(AR/AI)HeartFailurePericardialEffusion2循环系统常见症状体征英5/8/2024ValvesofHeartvalveannulus/valveringvalveleaflet/cuspmitr3循环系统常见症状体征英5/8/202444循环系统常见症状体征英5/8/2024Mfi1llUfl0fCló]f)YalvesofHeart•¿•Q@(heartindiastole:vie«edir0mbasewahariaemo•ec5循环系统常见症状体征英5/8/20246MitralStenosis(MS)Predominantlycausedbyrheumaticfever.6循环系统常见症状体征英5/8/20247mitralvalveareaMSnormalMVAmildmoderatesevere4~6cm21.5~2.0cm21.0~1.5cm2<1.0cm27循环系统常见症状体征英5/8/2024Normal----thecross-sectionalarea4~6cm2AbnormalMildMS -------orifice<2cm2bloodLA——→LVpropelledbyasmallandabnormalpressuregradient20mmHgModerateMS:--------orifice<1.5cm2PVP↑,PCWP↑,——→interstitialedemameansLVpressureof25mmHgSevereMS------orifice<1cm2PAP↑—→RVoverload—→RVfailure8循环系统常见症状体征英5/8/2024PathophysiologyCross-sectionalareaofthemitralvalveorifice↓Rateofbloodflowacrossthemitralorifice↑Leftatrialpressure↑DilationofLAPulmonaryvenousandcapillarypressures↑PulmonarycongestionandedemaPulmonaryhypertensionRight heart failureDyspnea2010ClinicalDiagnostics9循环系统常见症状体征英5/8/202410
LApressure↑
Pulmonarycirculationpressure↑
RightheartfailurePathophysiologydilationhypertrophyfailure10循环系统常见症状体征英5/8/202411Symptomsdyspnea: isdefinedasanabnormallyuncomfortableawarenessofbreathing.Thatisshortnessofbreath,difficultyinbreathing/laboredbreathing.Itisasubjectivesymptom.Itisoneof theprincipalsymptomsofcardiacandpulmonarydisease.11循环系统常见症状体征英5/8/2024Symptomsdyspneaexertional
dyspnea,dyspneaon
rest,paroxysmalnocturnal
dyspnea,orthopneapulmonaryedemacoughhemoptysis12循环系统常见症状体征英5/8/2024Iforthopneacausesawakeningduringthenight
andisrelievedbysitting,itiscalledparoxysmalnocturnal
dyspnea.Shortnessofbreathevenintheuprightpositionandcough
with
pink
frothysputum (粉红色泡沫痰) inpulmonary edema.13循环系统常见症状体征英5/8/2024Themostcommoncomplaintisshortnessofbreath, chieflyexertionaldyspneaatfirstandthenprogressingtorestdyspnea,paroxysmalnocturnal dyspnea, andorthopnea.14循环系统常见症状体征英5/8/2024PhysicalSigns1. Inspection2. Palpation3. Percussion4. Auscultation视触叩听2010ClinicalDiagnosticsMS15循环系统常见症状体征英5/8/202416Inspection:Mitral
facePatientsshow
malarflush (pinkish-purplepatchesonthecheeks)andlipcyanosis.Apexbeatdisplacestoleftbecause of
rightventricular
hypertrophy.二尖瓣面容16循环系统常见症状体征英5/8/202417PalpationDiastolicthrilloverapicalarea.tinyvibration,smallshaking17循环系统常见症状体征英5/8/202418PercussionCardiacdullnessbecomespear-shaped.18循环系统常见症状体征英5/8/202419梨形心,xrayfilm左房增大(左前斜位)19循环系统常见症状体征英5/8/202420AuscultationMidandlatediastolic
crescendorumblingmurmurinapical
area20循环系统常见症状体征英5/8/202421AuscultationAccentuated S1over
apical areaOpening
snapS2Splittingor
accentuatedGrahamSteell
murmurAhigh-pitcheddecrescendodiastolic
murmursecondarytopulmonaryregurgitation,canbeheard
inpulmonaryvalve
area.肺动脉瓣区 吹风样 舒张早期 杂音“二狭”导致
肺动脉压增高、肺动脉扩张 引起肺动脉瓣相对性关闭不全 所致的 功能性杂音 .21循环系统常见症状体征英5/8/202422MitralRegurgitation(MR)22循环系统常见症状体征英5/8/2024Mitralregurgitation(MR)isdefinedasanabnormalreversalofbloodflowfromtheleftventricle(LV)totheleftatrium(LA).Itiscausedbydisruptioninanypartofthemitralvalveapparatus.valveannulus/valve
ringvalveleaflet/
cusp23循环系统常见症状体征英5/8/202424Etiology★Mainlyrheumaticfever,★mitralvalveprolapse,infectiveendocarditis,calcification,ischemicheartdiseasewithpapillarymuscledysfunction,etal.24循环系统常见症状体征英5/8/2024SystolePathophysiologycompensatoryLAdilationpartofbloodinLVreturnstoLAmorebloodandpressure↑inLAInMRDiastoleLVreceivesnormalcontentregurgitantofbloodbothvolumeloadofLV↑compensatoryLVdilation2010ClinicalDiagnosticsMR25循环系统常见症状体征英5/8/2024WhenvolumeloadofLVcontinuouslyincreasingLVenddiastolicpressureandLApressureincreaseLeftheartfailurePulmonarycongestionandedema(肺淤血和肺水肿)PulmonaryhypertensionRightheartfailure26循环系统常见症状体征英5/8/202427
compensatorydilationofLA
compensatoryLVdilation
leftheartfailure
RightheartfailurePathophysiology27循环系统常见症状体征英5/8/2024EarlyStage------
asymptomatic------heartfailureLate
StagePalpitationCoughExertional
dyspneaFatigue/verygreat
tiredness(secondaryto↓cardiacoutput
)Symptoms2010ClinicalDiagnosticsMR28循环系统常见症状体征英5/8/2024PhysicalSignsInspectionApexbeatdisplacedtoleftanddownwardsPalpationApexbeatdisplacedtoleftanddownwards,heavingapexbeat, hyperdynamiccardiacimpulsePercussionTheareaofcardiacdullnessshiftstoleftanddownwardsatfirst,thentorightlater2010ClinicalDiagnosticsMR29循环系统常见症状体征英5/8/202430Auscultation:★Inapicalarea,harshblowingpansystolicmurmur,widelyspread,transmittingtoleftaxillaorsubscapularregion.★S1isweakenedandP2isaccentuatedandsplit.30循环系统常见症状体征英5/8/2024主动脉瓣狭窄(aorticstenosis,AS)EtiologyMainlycausedby rheumatic
fever.Others
caused
by
senile
calcification
orcongenitallybicuspidvalve
.31循环系统常见症状体征英5/8/2024图 主动脉瓣和冠状动脉开口示意图32循环系统常见症状体征英5/8/2024Aorticstenosis(AS)33循环系统常见症状体征英5/8/20242010ClinicalDiagnosticsASNormalcross-sectionalarea
3.0cm2<1.0cm2,
cross-sectional pressure﹥5
mmHgshowsclinical
signs.ASistheobstructionofbloodflowacrosstheaorticvalve.34循环系统常见症状体征英5/8/20242010ClinicalDiagnosticsAorticStenosis (AS)AS35循环系统常见症状体征英5/8/2024PathophysiologyAorticstenosisLV outflowobstruction↑LVsystolicpressure↓cardiacoutputLVhypertrophyLVdysfuctioncerebralischemiamyocardialischemiaLVfailure36循环系统常见症状体征英5/8/2024Early
stage------ asymptomatic.Late
stage ------ symptomsoccur
lateafteryearsof
obstruction.Symptoms2010ClinicalDiagnosticsAS37循环系统常见症状体征英5/8/2024(common)(relativelylate)Symptoms2010ClinicalDiagnosticsAngina
pectoris90%Syncope
(typical)60%Dyspnea30%AS38循环系统常见症状体征英5/8/2024Angina
pectoris (myocardial
ischemia)itiscommonlyprecipitated/inducedby
exertionandrelievedby
rest.Dyspnea (relativelylatesymptom
)exertionaldyspneawithorthopnea,
paroxysmalnocturnaldyspnea,andpulmonaryedemareflect
varyingdegreesofpulmonaryvenous
hypertension.39循环系统常见症状体征英5/8/202440Syncope (cerebralischemia)which maybedefinedasalossofconsciousness, results most commonly fromreducedperfusion of the brain.Syncopeis typicallyexertionalandmaybeduetoarrhythmias,hypotension,ordecreasedcerebralperfusionresultingfromincreasedbloodflowtoexercisingmusclewithoutcompensatoryincreaseincardiacoutput.40循环系统常见症状体征英5/8/2024signsInspection:Theapexbeatdisplacestoleftandbelow.Percussion:Thecardiacdullnessmaybenormalorshiftstoleftandbelow.41循环系统常见症状体征英5/8/2024palpationTheapicalimpulseis
forceful.Asystolic
thrillmaybepalpatedinthesecondintercostalspace
onrightsideofthesternum
.42循环系统常见症状体征英5/8/2024AuscultationThesystolicejectionmurmur,harsh
andrasping,canbe
heard intheaortic
areatransmittedtothe
neck.Aweak
A2,
or
paradoxical
splitting
S2
ispresent.43循环系统常见症状体征英5/8/20242010ClinicalDiagnosticsAorticregurgitation(AR)AR44循环系统常见症状体征英5/8/202445Etiology★ Mainlycausedby rheumaticfever;★ Sometimescausedbynon-rheumaticfeversuchasinfectiveendocarditis,congenitalvalvedeformity, valveprolapse,syphilis,Manfan’ssyndrome.45循环系统常见症状体征英5/8/2024PathophysiologyFromBraunwald'sHeartDisease8thARbloodreturningfromaortatoLVDBP↓morebloodliftupleafletsofmitralvalvebloodvolumeinLV↑compensatoryLVdilatationpulsepressure↑relativeMSAustin-FlintmurmurLVHeartFailureperipheralvascularsignsInsufficientofcoronaryartery2010ClinicalDiagnosticsAR46循环系统常见症状体征英5/8/2024SymptomsEarlystage--------
asymptomatic.Latestage
--------PalpitationFatigueDizzinessAngina
pectorisExertional
dyspnea2010ClinicalDiagnosticsAR47循环系统常见症状体征英5/8/2024SignsInspectionFacemaybepale;Apexbeatdisplacedtoleftandbelow.PalpationApexbeatisratherdiffuseanddisplacestodownwards and left; /heavingapeximpulsePercussioncardiacdullness------shapeofaboot2010ClinicalDiagnosticsAR48循环系统常见症状体征英5/8/2024AuscultationSighingdiastolicdecrescendo
murmur,canbeheardinthe2ndaortic
area.Austin-FlintmurmurArumblingmid-diastolicmurmurcaused
byrelativeMS,canbeheardovertheapex
area.(主动脉瓣关闭不全时回流血液限制二尖瓣开放所致)2010ClinicalDiagnosticsAR49循环系统常见症状体征英5/8/2024---------causedby↑pulsepressure
Headbobbing
Visiblepulsationofcarotidarteries
Signsofcapillarypulsation
Waterhammerpulse
PistolshotsoundsoverfemoralarteriesandDuroziez’murmurPeripherialVascularSigns2010ClinicalDiagnosticsAR50循环系统常见症状体征英5/8/202451循环系统常见症状体征英5/8/202452HeartFailureBriefaccount:★Incertainpathologicalcircumstances,ifcardiacoutputisbelowthelevelofadaptationtotheneedsofhumanbody,heartcannotmaintaineffectivecirculation.Thereforeaseriesofsymptomsandsignsdevelop.52循环系统常见症状体征英5/8/202453★ Classifiedasacuteandchronicheartfailureaccordingtoitsclinicalcourse.★ Classifiedasleft,rightand bilateralheartfailureaccordingtotheclinicalmanifestations.53循环系统常见症状体征英5/8/202454Leftheartfailure★ Themainpathologicalchangeispulmonarycongestion,pulmonary edemadevelopsinseverecases.54循环系统常见症状体征英5/8/202455Symptoms★Dyspnea:Exertional
dyspnea;Paroxysmalnocturnal
dyspnea;Orthopnea;Coughwithpinkfrothysputum(粉红色
泡沫痰)inpulmonaryedema
;★
Cough
withsputum
or
cough
with
bloodstained
sputum.55循环系统常见症状体征英5/8/202456Signs★ Inspection:Tachypnea(呼吸急促),cyanosisandorthopnea;★ Percussion:Signsofprimaryheartdiseases;56循环系统常见症状体征英5/8/2024★ Auscultation:Findingsofprimaryorganic
heart
diseases;Fastheartrateanddiastolic
galloprhythm
;
moistrales
(湿罗音)
at
the
lung
bases
;
in
pulmonary
edema
bubble
and
wheezing
rales
(哮鸣音)
over
both
lungs.5757循环系统常见症状体征英5/8/202458RightventricularfailureBriefaccount:★Themainpathologicalchangeissystemiccongestion(体循环淤血).58循环系统常见症状体征英5/8/202459Symptoms★Edema(水肿)occursinthelowerpartofbody(abdomen,thelowerextremities).★Bloat(胃胀),nausea(恶心),anorexia(食欲不振),oliguria少尿.59循环系统常见症状体征英5/8/202460Signs★Inspection:Dilatationofthejugularvein.60循环系统常见症状体征英5/8/2024Cyanosisandedemainthelower
partof body.61循环系统常见症状体征英5/8/202462★Palpation:Enlargementofliverwithtenderness,positivehepatojugularreflux(肝颈静脉回流征阳性).★ Percussion:Pleuraleffusion(胸腔积液)andascites(腹水);signsofprimaryheartdiseases.62循环系统常见症状体征英5/8/202463★Auscultation:Signsofprimaryheart diseases.63循环系统常见症状体征英5/8/202464PericardialeffusionBriefaccount:★Maybecausedbyinfectivepericardialchangessuchastuberculosis(肺结核)andnon-infectivepericardialchangessuchast
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