Nebivolol-hydrochloride-Standard-R-065824-hydrochloride-Standard-DataSheet-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors • ScreeningLibraries • Proteinswww.MedChemENebivololhydrochloride(Standard)Cat.No.:HY-B0203ARCASNo.:152520-56-4Synonyms:R065824hydrochloride(Standard)分子式:C₂₂H₂₆ClF₂NO₄分子量:441.9作用靶点:AdrenergicReceptor作用通路:GPCR/GProtein;NeuronalSignaling储存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.溶解性数据体外实验DMSO:100mg/mL(226.30mM;Needultrasonic)H2O:1.79mg/mL(4.05mM;ultrasonicandwarmingandheatto60°C)SolventMass1mg5mg10mgConcentration制备储备液1mM2.2630mL11.3148mL22.6296mL5mM0.4526mL2.2630mL4.5259mL10mM0.2263mL1.1315mL2.2630mLBIOLOGICALACTIVITY生物活性Nebivolol(hydrochloride)(Standard)是Nebivolol(hydrochloride)的分析标准品。本产品用于研究及分析应用。Nebivolol(R065824)hydrochloride是一种β受体阻滞剂，具有口服活性和高β(1)-受体亲和力。Nebivololhydrochloride具有直接的血管扩张剂特性和肾上腺素能阻断特性。Nebivololhydrochloride可用于高血压、冠状动脉疾病、充血性心力衰竭和缺血性心脏病等多种疾病的研究。REFERENCES1/2 MasterofBioactiveMolecules—您身边的抑制剂大师www.MedChemEBrehmBR,etal.Effectsofnebivololonproliferationandapoptosisofhumancoronaryarterysmoothmuscleandendothelialcells.CardiovascRes.2001Feb1;49(2):430-9.ThomasMünzel,etal.Nebivolol:thesomewhat-differentbeta-adrenergicreceptorblocker.JAmCollCardiol.2009Oct13;54(16):1491-9.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792Fax:021-