6-Methoxyflavone-Standard-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors•ScreeningLibraries•Proteinswww.MedChemE6-Methoxyflavone(Standard)Cat.No.:HY-W097625RCASNo.:26964-24-9分⼦式:C₁₆H₁₂O₃分⼦量:252.27作⽤靶点:Toll-likeReceptor(TLR);MyD88;p38MAPK;NF-κB;ReferenceStandards;HemeOxygenase(HO);PERK作⽤通路:Immunology/Inflammation;MAPK/ERKPathway;NF-κB;Others;MetabolicEnzyme/Protease;CellCycle/DNADamage储存⽅式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY⽣物活性6-Methoxyflavone(Standard)6-Methoxyflavone(HY-W097625)的分析标准品。本产品⽤于研究及分析应⽤。6-Methoxyflavone⼀种具有⼝服活性的甲氧通过抑制TLR4/MyD88/p38MAPK/NF-κB依赖途径和激活HO-1/NQO-1信号通路，抑制⼩胶质细胞中的神经炎症。6-Methoxyflavone通过CCNA2/CDK2/p21CIP1<REFERENCES[1].ZhangC,QuanY,YangL,BaiY,YangY.6-MethoxyflavoneinducesS-phasearrestthroughtheCCNA2/CDK2/p21CIP1signalingpathwayinHeLacells.Bioengineered.2022Mar;13(3):7277-7292.[2].ArifM,RaufK,RehmanNU,TokhiA,IkramM,SewellRD.6-MethoxyflavoneandDonepezilBehavioralPlusNeurochemicalCorrelatesinReversingChronicEthanolandWithdrawalInducedCognitiveImpairment.DrugDesDevelTher.2022May28;16:1573-1593.[3].ChenWF,etal.6-methoxyflavonesuppressesneuroinflammationinlipopolysaccharide-stimulatedmicrogliathroughtheinhibitionofTLR4/MyD88/p38MAPK/NF-κBdependentpathwaysandtheactivationofHO-1/NQO-1signaling.Phytomedicine.2022May;99:154025.[4].ShahidM,etal.6-Methoxyflavoneantagonizeschronicconstrictioninjuryanddiabetesassociatedneuropathicnociceptionexpression.BiochemBiophysResCommun.2024Sep10;724:150217.[5].SoJS,etal.6-MethoxyflavoneinhibitsNFATtranslocationintothenucleusandsuppressesTcellactivation.JImmunol.2014Sep15;193(6):2772-83.[6].ZhangC,etal.Theeffectandapoptosismechanismof6-methoxyflavoneinHeLacells.Biomarkers.2022Jul;27(5):470-482.[7].HallBJ,etal.ModulationofionotropicGABAreceptorsby6-methoxyflavanoneand6-methoxyflavone.NeurochemRes.2014Jun;39(6):1068-78.[8].ZhangC,etal.6-MethoxyflavoneinhibitsglycolyticenergymetabolisminHeLacells.BMCCancer.2025Apr17;25(1):719.1/2MasterofBioactiveMolecules—您⾝边的抑制剂⼤师www.MedChemEMcePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuse