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Electrocardiography A recording of the electrical activity of the heart over time Gold standard for diagnosis of cardiac arrhythmias Helps detect electrolyte disturbances (hyper- i.e., it requires two sensors on the skin to make a lead. If one connects a line between two sensors, one has a vector. There will be a positive end at one electrode and negative at the other. The positioning for leads I, II, and III were first given by Einthoven. Form the basis of Einthovens triangle.Types of ECG Recordings Bipolar leads record voltage between electrodes placed on wrists Relationship between P and QRS helps distinguish various cardiac arrhythmias Shape and duration of P may indicate atrial enlargement PR interval: from onset of P wave to onset of QRS Normal duration = 0.12-2.0 sec (120-200 ms) (3-4 horizontal boxes) Represents atria to ventricular conduction time (through His bundle) Prolonged PR interval may indicate a 1st degree heart block QRS complex: Ventricular depolarization Larger than P wave because of greater muscle mass of ventricles Normal duration = 0.08-0.12 seconds Its duration, amplitude, and morphology are useful in diagnosing cardiac arrhythmias, ventricular hypertrophy, MI, electrolyte derangement, etc. Q wave greater than 1/3 the height of the R wave, greater than 0.04 sec are abnormal and may represent MI ST segment: Connects the QRS complex and T wave Duration of 0.08-0.12 sec (80-120 msecT wave: Represents repolarization or recovery of ventricles Interval from beginning of QRS to apex of T is referred to as the absolute refractory periodQT Interval Measured from beginning of QRS to the end of the T wave Normal QT is usually about 0.40 sec QT interval varies based on heart rateFig. 13.24bFig. 13.24cFig. 13.24dElements of the ECG: P wave Depolarization of both atria; Relationship between P and QRS helps distinguish various cardiac arrhythmias Shape and duration of P may indicate atrial enlargementQRS complex: Represents ventricular depolarization Larger than P wave because of greater muscle mass of ventricles Normal duration = 0.08-0.12 seconds Its duration, amplitude, and morphology are useful in diagnosing cardiac arrhythmias, ventricular hypertrophy, MI, electrolyte derangement, etc. Q wave greater than 1/3 the height of the R wave, greater than 0.04 sec are abnormal and may represent MI PR interval: From onset of P wave to onset of QRS Normal duration = 0.12-2.0 sec (120-200 ms) (3-4 horizontal boxes) Represents atria to ventricular conduction time (through His bundle) Prolonged PR interval may indicate a 1st degree heart blockFig. 13.24gT wave: Represents repolarization or recovery of ventricles Interval from beginning of QRS to apex of T is referred to as the absolute refractory periodST segment: Connects the QRS complex and T wave Duration of 0.08-0.12 sec (80-120 msecQT Interval Measured from beginning of QRS to the end of the T wave Normal QT is usually about 0.40 sec QT interval varies based on heart rateIschemic Heart Disease Is most commonly due to atherosclerosis in coronary arteries Ischemia occurs when blood supply to tissue is deficient Causes increased lactic acid from anaerobic metabolism Often accompanied by angina pectoris (chest pain)13-78Click here to playMyocardial InfarctionRealMedia MovieIschemic Heart Disease Detectable by changes in S-T segment of ECG Myocardial infarction (MI) is a heart attack Diagnosed by high levels of creatine phosphate (CPK) & lactate dehydrogenase (LDH)Fig 13.3413-79Arrhythmias Detected on ECG Arrhythmias are abnormal heart rhythms Heart rate 100/min is tachycardiaFig 13.3513-80Arrhythmias Detected on ECG continued In flutter contraction rates can be 200-300/min In fibrillation contraction of myocardial cells is uncoordinated & pumping ineffective Ventricular fibrillation is life-threatening Electrical defibrillation resynchronizes heart by depolarizing all cells at same time Fig 13.3513-81 AV node block occur when node is damaged Firstdegree AV node block is when conduction through AV node 0.2 sec Causes long P-R interval Second-degree AV node block is when only 1 out of 2-4 atrial APs can pass to ventricles Causes P waves with no QRS In third-degree or complete AV node block no atrial activity passes to ventricles Ventricles driven slowly by bundle of His or PurkinjesArrhythmias Detected on ECG continued13-82 AV node block occurs when node is damaged Firstdegree AV node block is when conduction thru AV node 0.2 sec Causes long P-R intervalArrhythmias Detected on ECG continuedFig 13.3613-83 Second-degree AV node block is when only 1 out of 2-4 atrial APs can pass to ventricles Causes P waves with no QRS

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