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Hypertension Blood Pressure Management Facts, Myths 43:10-17 British Hypertension Society Guidelines for hypertension management (BHS-IV): summary (2004) Bryan Williams, Neil R Poulter, Morris J Brown, Mark Davies, Gordon T McInnes, John F Potter, Peter S Sever, Simon McG Thom; the BHS guidelines working party, for the British Hypertension Society. BMJ 328 634-640. Joint British Societies Guidelines on Prevention of Cardiovascular Disease in Clinical Practice (2006) British Cardiac Society, British Hypertension Society, Diabetes UK. HEART UK, Primary Care Cardiovascular Society, The Stroke Association. 91 Supl. V Hypertension-management of hypertension in adults in primary care (2004 and 2006). NICE. Clinical guideline 18 and 34 .uk Guidelines GuidelinesGuidelines Topics to be covered Definition, Thresholds for intervention and treatment goals Measurement Evaluation of hypertensive patients Lifestyle measures ABPM and home monitoring Classification of blood pressure levels of the British Hypertension Society Category Systolic blood pressure (mmHg) Diastolic blood pressure (mmHg) Blood Pressure Optimal 180 110 Isolated systolic hypertension Grade 1 140-159 160 140 systolic and/or 90 mmHg diastolic. Medication Required if; Sustained raised BP 160 systolic and/or 100 mmHg diastolic (despite non-pharmacological treatment) OR if BP 140 systolic and/or 90 diastolic AND patient has Target Organ Damage, CVD, Diabetes or 10 year CVD risk 20% When to treat? Suggested target blood pressures during antihypertensive treatment. Clinic BP (mmHg) No diabetes Diabetes Optimal treated BP 10mmHg difference in systolic If 5mmHg difference in diastolic The patient to be seated for at least 5 minutes The monitor cuffs, bulbs and tubing shouldnt leak If using mercury; column-vertical clean Assessment of hypertension NICE BP confirmation If Initial BP 140/90 repeat monthly for 2 months BHS Measure every 5 years all adults up to 80 years Measure annually those high normal (130-139 or 85-89) and anyone noted to have high readings at any time Confirmation of hypertension If BP high repeat monthly over 4-6 months. (Unless BP very high, then measure more frequently) Do not treat on the basis of an isolated reading BHS Guidelines Definitions Measurement Evaluation of hypertensive patients Lifestyle measures ABPM and home monitoring Urine strip test for protein and blood Serum creatinine and electrolytes Blood glucose ideally fasted Blood lipid profile ideally fasted for consideration of triglycerides Electrocardiogram Routine investigations Evaluation of hypertensive patients Causes of hypertension Drugs (NSAIDS, oral contraceptions, steroids, liquorice, some cold cures) Renal disease (present, past or family history, proteinuria or haematuria: palpable kidney(s) polycystic, hydronephrosis, or neoplasm) Renovascular disease (abdominal or loin bruit) Phaeochromocytoma (paroxysmal symptoms) Conns syndrome (muscle weakness, polyuria, hypokalaemia) Coarctation (radio-femoral delay or weak femoral pulses) Cushings (general appearance) Overweight Excess alcohol ( 3 units/day for men; 2 units/days for women) Excess salt intake Lack of exercise Environmental stress Contributory factors Suggested indications for specialist referral (part 1) Urgent treatment needed Accelerated hypertension (severe hypertension and grade III-IV retinopathy) Particularly severe hypertension (220/120mmHg) Impending complications (e.g. TIA, LVF) Possible underlying cause Any clue in history or examination of a secondary cause, eg. low potassium with increased or high normal plasma sodium (Conns syndrome) Raised serum creatinine Proteinuria or haematuria Sudden onset or worsening of hypertension Resistant to multi-drug regimen ( 3 drugs) Young age (any hypertension 20 years; needing treatment 30 years) Suggested indications for specialist referral (continued) Therapeutic problems Multiple drug intolerance Multiple drug contraindications Persistent non-adherence or non-compliance Special situations Unusual blood pressure variability Possible white coat hypertension Hypertension in pregnancy Suggested indications for specialist referral (continued) BHS Guidelines Definitions Measurement Evaluation of hypertensive patients Lifestyle measures ABPM and home monitoring Myth Stopping smoking reduces high blood pressure - Smoking is a contributory factor for cardiovascular disease FACT: Lifestyle intervention for blood pressure reduction Intervention Recommendation Expected systolic BP reduction (range) Weight reduction Maintain ideal body mass index (20- 25kg/M) 5-10 mmHg per 10kg weight loss DASH eating plan Eat diet rich in fruit, vegetables, low-fat dairy products. Eat less saturated and total fat 8 -14 mmHg Dietary sodium restriction Reduce dietary sodium intake to 100mmol/day 2.4g sodium or 6 g salt (sodium chloride) 2 - 8mmHg Physical activity Regular aerobic physical activity, e.g. brisk walking for at least 30 min most days 4 - 9 mmHg Alcohol moderation Men 21 units per week Women 14 units per week 2-4 mmHg BHS Guidelines Definitions Measurement Evaluation of hypertensive patients Lifestyle measures ABPM and home monitoring Home/self BP monitoring Advise patients on accurate, independently validated, well maintained monitors Advise use of appropriate cuff size Wrist monitors are not recommended Suggested measurement routine for patients Measure BP for 7 days prior to appointment Record BP twice a day. Morning and evening Discard first 24 hours of readings Take an average of at least 12 of these readings BHS IV, 2004 Indications for ABPM 24 hour BP monitoring (ABPM) Possible white coat hypertension Informing equivocal treatment decisions Evaluation of nocturnal hypertension Determining efficacy of drug treatment over 24 hours Evaluation of symptomatic hypotension Unusual BP variability Diagnosis & treat

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