DBCO-NHS-ester-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEDBCO-NHS esterCat. No.: HY-42973CAS No.: 1353016-71-3分式: CHNO分量: 402.4作靶点: ADC Linker作通路: Antibody-drug Conjugate/ADC Related储存式: -20C, stored under nitrogen* In solvent : -80C, 6 months; -20C, 1 month (stored undernitrogen)溶解性数

2、据体外实验 DMSO : 100 mg/mL (248.51 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.4851 mL 12.4254 mL 24.8509 mL5 mM 0.4970 mL 2.4851 mL 4.9702 mL10 mM 0.2485 mL 1.2425 mL 2.4851 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验 请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄的储备液，再依次添加助溶剂(为保证实验

3、结果的可靠性，体内实验的作液，建议您现现配，当天使；澄的储备液可以根据储存条件，适当保存；以下溶剂前的百分指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (6.21 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.5 mg/mL (6.21 mM); Clear solution3. 请依序添加每种溶剂： 10% DMSO 90% cor

4、n oilSolubility: 2.5 mg/mL (6.21 mM); Clear solution1/2 Master of Small Molecules 您边的抑制剂师www.MedChemEBIOLOGICAL ACTIVITY物活性 DBCO-NHS ester种可降解 (cleavable) 的 ADC 连接桥，于抗体药物结合物 (ADCs) 的合成。IC50 & Target Cleavable体外研究 ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC

5、linker.REFERENCES1. Method for identifying potential drug target protein useful for development of antibody drug, and method for producing antibody directedagainst target protein. WO2018151301A1.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 021-5895