Posaconazole-Standard-SCH-56592-Standard-DataSheet-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors • ScreeningLibraries • Proteinswww.MedChemEPosaconazole(Standard)Cat.No.:HY-17373RCASNo.:171228-49-2Synonyms:SCH56592(Standard)分子式:C₃₇H₄₂F₂N₈O₄分子量:700.78作用靶点:Fungal;Parasite作用通路:Anti-infection储存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.溶解性数据体外实验DMSO:18.75mg/mL(26.76mM;ultrasonicandwarmingandheatto60°C)SolventMass1mg5mg10mgConcentration制备储备液1mM1.4270mL7.1349mL14.2698mL5mM0.2854mL1.4270mL2.8540mL10mM0.1427mL0.7135mL1.4270mLBIOLOGICALACTIVITY生物活性 Posaconazole(Standard)是Posaconazole的分析标准品。本产品用于研究及分析应用。Posaconazole是一种广谱的，二代三唑类物质，具有抗真菌作用。REFERENCESBenaimG,etal.Amiodaronehasintrinsicanti-Trypanosomacruziactivityandactssynergisticallywithposaconazole.JMedChem.2006Feb9;49(3):892-9.SabatelliF,etal.Invitroactivitiesofposaconazole,fluconazole,itraconazole,voriconazole,andamphotericinBagainstalargecollectionofclinicallyimportantmoldsandyeasts.AntimicrobAgentsChemother.2006Jun;50(6):2009-15.1/2 MasterofBioactiveMolecules—您身边的抑制剂大师www.MedChemESansone-ParsonsA,etal.Effectofanutritionalsupplementonposaconazolepharmacokineticsfollowingoraladministrationtohealthyvolunteers.AntimicrobAgentsChemother.2006May;50(5):1881-3.Veiga-SantosP,etal.EffectsofamiodaroneandposaconazoleonthegrowthandultrastructureofTrypanosomacruzi.IntJAntimicrobAgents.2012Jul;40(1):61-71.SunQN,etal.InvivoactivityofposaconazoleagainstMucorspp.inanimmunosuppressed-mousemodel.AntimicrobAgentsChemother.2002Jul;46(7):2310-2.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792;021-5