Quinolinic-acid-Standard-DataSheet-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors • ScreeningLibraries • Proteinswww.MedChemEQuinolinicacid(Standard)Cat.No.:HY-100807RCASNo.:89-00-9分子式:C₇H₅NO₄分子量:167.12作用靶点:EndogenousMetabolite;iGluR作用通路:MetabolicEnzyme/Protease;MembraneTransporter/IonChannel;NeuronalSignaling储存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.溶解性数据体外实验DMSO:33.33mg/mL(199.44mM;Needultrasonic)H2O:3.33mg/mL(19.93mM;Needultrasonic)MassSolvent1mg5mg10mgConcentration制备储备液1mM5.9837mL29.9186mL59.8372mL5mM1.1967mL5.9837mL11.9674mL10mM0.5984mL2.9919mL5.9837mLBIOLOGICALACTIVITY生物活性Quinolinicacid(Standard)是Quinolinicacid的分析标准品。本产品用于研究及分析应用。Quinolinicacid是一种内源性的N-甲基-D-天冬氨酸受体(NMDAreceptor)激动剂，通过犬尿氨酸途径从L-色氨酸合成，因此具有调节N-甲基-D-天冬氨酸神经元损伤和功能障碍的潜力[1][2]。IC50&TargetNMDAReceptor[1]客户使用本产品发表的科研文献1/2 MasterofBioactiveMolecules—您身边的抑制剂大师www.MedChemEHepatology.2022Jul11.CellRep.2022Mar8;38(10):110462.Metabolites.2023Dec12,13(12),1196.Seemorecustomervalidationsonwww.MedChemEREFERENCESHeyesMP,etal.Quinolinicacidandkynureninepathwaymetabolismininflammatoryandnon-inflammatoryneurologicaldisease.Brain.1992Oct;115(Pt5):1249-73.JangS,etal.Neuroprotectiveeffectsof(-)-epigallocatechin-3-gallateagainstquinolinicacid-inducedexcitotoxicityviaPI3KpathwayandNOinhibition.BrainRes.2010Feb8;1313:25-33.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792Fax