婴幼儿支气管肺炎患儿血清心肌酶变化及其临床意义.doc

110803022Olympus AU 2700(AST)(LDH)(-HBDH)CKCK-MB ASTLDH-HBDHCKCK-MBP<0.01P<0.01 Abstract:Objectives To investigation the variations of blood serum myocardial enzymes in infants and young children with bronchial pneumonia so as to take comprehensive measures in diagnosis and treatment.Methods 110 hospitalized infants and young children of 1 month to 3 years suffering from bronchial pneumonia were included in this study, of whom 80 cases had mild conditions (mild group) and 30 cases had severe conditions (severe group). 22 healthy young children were designated as control group. An Olympus AU 2700 auto-analyzer was used to determine the myocardial enzyme indexes in the acute stage and convalescence, including aspartate aminotransferase (AST), lactate dehydrogenase (LDH), -hydroxybutyrase dehydrogenase (-HBDH), creatine kinase (CK) and creatine kinase myocardial bound (CK-MB) in the young patients.Results Compared with the control group, the levels of AST, LDH, -HBDH, CK and CK-MB in both the pneumonia groups (P<0.01). The above indexes in the severe group were markedly higher than the mild group (P<0.01). Compared with the acute stage, all the myocardial enzyme indexes in the convalescence tend to be normal. Conclusion The blood serum myocardial enzymes of infants and young children with bronchial pneumonia increase in different degrees. There is a positive correlation between the severity and the levels of myocardial enzymes. 122006320077110 1 1.1 110380453513.510.63020101.53.19.82213923.19.5 1.2 (AST)(LDH)-(-HBDH)CKCK-MB324 h3 ml,2 h11082Olympus AU2700Olympus 1.3 sSPSS 10.0qtP<0.05 2 2.1 P<0.01P<0.0111 *P<0.01#P<0.01 2.2 P<0.0122 *P<0.01 3 ASTLDH-HBDHCKCK-MB2ATPCK-MB