胸腺五肽和常规抗结核药物在初治菌阳肺结核中应用效果.doc

胸腺五肽和常规抗结核药物在初治菌阳肺结核中应用效果 张雪元 阜新市传染病医院呼吸科，辽宁阜新123000 摘要目的探究胸腺五肽和常规抗结核药物治疗初治菌阳肺结核的临床效果。方法资料随机选取xx年6月xx年6月该院收治的95例初治菌阳肺结核患者，随机分为研究组与对照组，对照组行常规抗结核药物治疗，研究组在此基础上行胸腺五肽治疗，分析两组治疗效果。结果研究组治疗后2个月痰菌转阴率高于对照组，病灶吸收率97.92%高于对照组79.60%，差异有统计学意义（P0.05）；治疗后CD3+(0.730.08)、CD4+(0.520.06)、CD4+/CD8+(1.680.24)水平均高于对照组,差异有统计学意义（P0.05）。结论胸腺五肽联合常规抗结核药物治疗初治菌阳肺结核疗效确切，可显著促进病灶吸收，提高致病菌转阴率。 关键词初治菌阳肺结核;胸腺五肽;抗结核药物;治疗;效果 R521A1674-074（5）01（c）118-02 Thymopentinandconventionalanti-TBdrugapplicationresultsinnewlydiagnosedsmear-positivepulmonarytuberculosis ZHANGXueyuan FuxincityhospitalofinfectiousdiseasesLiaoningfuxin123000，China AbstractObjectiveToexploreThymopentinandconventionalanti-TBdrugtreatment-na?vesputumpositiveclinicalresults.MethodsDatawererandomlyselectedinJunexx-xxourhospitalJune95newlydiagnosedsputumpositivepulmonarytuberculosispatientswererandomizedintothestudygroupandthecontrolgroup,thecontrolgroupunderwentconventionalanti-TBdrugs,thestudygrouponthebasisofthethymusuppentapeptidetreatment,analyzetheeffectofthetwogroups.ResultsStudygroupaftertwomonthsoftreatmentsputumnegativeratewashigher,focusabsorptionrateof97.92percenthigherthan79.60%,asignificantdifferencewasstatisticallysignificant(P0.05);CD3+(0.730.08)aftertreatment,CD4+(0.520.06),CD4+/CD8+(1.680.24)lev