Biomedical Engineering.doc

Biomedical Engineering at The University of Michigan U M BME is becoming one of the premier biomedical engineering departments in the country Our faculty lead a wide range of programs in biofluid mechanics microfluidics biologic micro and nanotechnology BioMEMS biomaterials biomolecular machines tissue engineering biomedical optics biotechnology biomechanics and biomedical imaging U M BME is one of the largest BME graduate program in the U S and has awarded more graduate degrees than any other BME department in the country The BME program at the University of Michigan also offers an undergraduate program for students in the College of Engineering The Biomedical Engineering BME Department occupies three state of the art research and educational facilities on the University of Michigan s North Campus the Ann and Robert H Lurie Biomedical Engineering Building the Carl A Gerstacker Building and the Bonisteel Interdisciplinary Research Building housing the fMRI Center The generous support of The Ann and Robert H Lurie Foundation The Whitaker Foundation and The Rollin M Gerstacker Foundation has allowed U M BME to grow enormously with new faculty facilities students and degree programs The BME Department continues to foster collaborations among College of Engineering faculty and researchers throughout the University As a Wallace H Coulter Foundation Translational Research Partner the department is able to strategically enhance our ability to promote develop and realize the potential of clinical research Commercialization of new BME technologies is enhanced by access to the resources of the U of M s top ranked business school and its worldclass entrepreneurship institute In addition to our two North Campus buildings devoted to bioengineering research and education we have access to extensive core facilities in both the College of Engineering and the Medical School Shared resources include fully equipped tissue culture facilities small animal facilities with holding and procedure areas access to multiple microscopy systems such as confocal and TIRF instruments as well as medical imaging systems such as real time ultrasound and optical scanners and a 3T whole body MRI scanner The Michigan Nanofabrication Facility one of the best university facilities in the country for the design and manufacture of microelectronic circuits is used extensively for implantable biosensor transducers and bioMEMS devices A new addition to the clean room more than doubling current space is already underway Our Functional MRI Center combines cognitive neuroscience clinical neuroscience and biomedical engineering research Our Center for Neural Communication Technology CNCT develops neural probe technologies for interfaces to the central nervous systems The College of Engineering in conjunction with university administration has made significant commitments to develop the BME Department into a premier research and educational department that helps define the rapidly evolving discipline of bioengineering Our long term programmatic themes are molecular engineered biosystems biomedical micro and nanosystems as well as cellular and molecular biomechanics S P O T L I G H T Understanding how cancer spreads Nanotech single cell monitoring technique could give insights Published on Dec 14 2011 Written by Nicole Casal Moore ANN ARBOR Mich A technique that lets researchers monitor single cancer cells in real time as they float in liquid could help doctors study the breakaway tumor cells that cause metastasis Metastasis is the process of the disease spreading through the body The approach developed at the University of Michigan could also pave the way for new types of targeted therapies that go beyond personalized medicine researchers say Remy Elbez a doctoral student in applied physics takes a sample of a solution that contains magnetized cervical cancer cells He will place several drops of the solution in a special magnetic field Then after placing the whole apparatus under a microscope he can watch the cells spin on a screen and determine their shape and status from their rotation rates This new technique could help doctors understand the process of cancer metastasis Photo by Nicole Casal Moore We re looking toward individualized treatment not just to the person but to the cell said Remy Elbez a doctoral student in applied physics He is a co author of a paper on the work published Dec 13 in PLoS ONE In recent years researchers have come to understand that not all cells in a cancerous tumor share the same genetic code This means some are more difficult to kill than others And techniques that enable single cell study are in demand Approaches that process many cells at once aren t as useful for researchers who want to look for example at a small number of cells that a particular cancer drug left alive One particularly dangerous type of cancer cell that scientists want to know more about is the circulating tumor cell These cells have separated from the original tumor and set off in the bloodstream to invade distant tissues Scientists know that they re different from the cells that stay put They don t divide rapidly for example At the same time they re difficult to study for several reasons They re hard to find because they only make up less than one in a trillion blood cells And they operate in motion so tamping them down to a Petri dish doesn t reveal their true nature More N E W S BME Prof Sherman Fan and Yuze Sun featured for hot paper A paper by U M BME professor Xudong Sherman Fan and his Ph D student Yuze Sun titled Distinguishing DNA via analog to digital like conversion using optofluidic lasers was accepted for publication by Angewandte Chemie International Edition In addition the paper was selected as one of the publications hot papers to appear in an upcoming edition Hot Papers are chosen by the editors for their importance in a rapidly evolving field of high current interest Angewandte Chemie International Edition with its excellent Impact Factor of 12 730 2010 strengthens its leading position among the general chemistry journals It is one of the prime chemistry journals in the world with the highest Impact Factor among chemistry specific journals that publish original research More BME News Breakthrough Researchers find wide gap in immune responses of people who did or didn t get the flu after exposure by Laura Bailey NS ANN ARBOR Mich Why do some folks who take every precaution still get the flu while others never even get the sniffles It comes down to a person s immune system response to the flu virus says Alfred Hero professor at the University of Michigan College of Engineering In one of the first known studies of its kind Hero and colleagues from Duke University Medical Center and the Duke Institute for Genome Sciences a device that mimics the blood brain barrier for use in drug testing neural probes to treat Parkinson s with deep brain stimulation computer models that suggest how complex proteins are assembled waveforms to image the body with MRI ultrasound therapies to treat tumors non invasively injectible stem cell cultures to regenerate damaged tissue In fact these are all projects undertaken by faculty and students in this department Biomedical engineers require a solid foundation in the biological sciences as well as a firm grasp of engineering principles and techniques A strong BME program introduces students not only to these disciplines but also to laboratory research and instrumentation the design process teamwork technical communication entrepreneurship and legal and regulatory issues It is important for students to have access to interconnected engineering medical and business resources BME at a Glance Education U M BME is one of the largest BME graduate programs in the U S and has awarded more graduate degrees than any other BME department in the country U M is one of the only universities in the country with top ranked engineering medical and business schools on the same campus U M BME is ranked 10 in undergraduate education by US News and World Report 2011 U M BME is ranked 12 in graduate education by US News and World Report 2010 U M BME is accredited by the Engineering Accreditation Commission of ABET http www abet org one of only 71 BME Departments to achieve ABET accreditation U M BME has six graduate concentrations bioelectrics biomaterials biomechanics biotechnology biomedical imaging and ergonomics and rehabilitation engineering U M BME has combined an undergraduate graduate program in one of three concentrations biochemical bioelectrics biomechanics Research state of the art research facilities for our faculty and students with access to a variety of biomedical labs throughout the U M College of Engineering and the Medical School We are the home o U M BME s Lurie Biomedical Engineering building and the Carl Gerstacker building include f the NIH funded Center for Neural Communication The Wallace H Coulter Foundation along with the College of Engineering and the Medical School has enabled the creation of a 20 million endowment to enhance and support research directed at technologies promising progression towards commercial development and clinical practice Every core faculty member is involved in translational research with distinguished medical clinicians on a variety of projects We are consistently ranked in the top ten for NIH research funding U M BME has the sixth highest total research expenditures of all BME departments U M BME has the third highest research expenditures per faculty member of all BME departments Personnel 200 students in the BS program 200 students in the graduate program 15 tenured or tenure track faculty members with primary appointments in BME 68 tenured or tenure track faculty members with secondary appointments in BME 4 non teaching full time research faculty 6 non teaching research staff 16 administrative staff Location a five year sequential graduate undergraduate study program leading to a master s of science in engineering MSE and graduate programs leading to an MSE or PhD degree RESEARCH Our departmental research goals embrace the biggest clinical need mentality We are fostering synergies with other U M units to address the major health concerns of our time such as diabetes cancer cardio vascular and neurological disease and global challenges like malaria To this end we are enriching our existing expertise with an increased presence in six key areas neuroengineering molecular and nanoscale engineering tissue engineering computational and systems physiology and engineering molecular and functional imaging and image guided therapy and diagnostics and therapeutics for personalized medicine Please explore specific faculty labs and research areas for additional detail on the projects our faculty are undertaking INDUSTRY and PhD and Post doc candidates to help employers connect to our graduating students who are interested in full time employment Please email Lisa Waples lisa to obtain one or both of the books Corporate Information Sessions One time sessions providing focused information on your company to biomedical engineering students Contact Boyang Zhao BMES President at zhaob umich edu Job postings for BME students Opportunities for internship co op and full time opportunities are advertised to students through the BME department Contact Lisa Waples lisa On Campus Recruiting The Engineering Career Resource Center provides services for on campus recruiting Visit http career engin umich edu to schedule a visit GIVING U M s Department of Biomedical Engineering has remained at the forefront of the field thanks in no small part to the resources ava