二乙醇胺(DEA)和化妆产品.doc

原文：Diethanolamine and Cosmetic ProductsThe National Toxicology Program (NTP) completed a study in 1998 that found an association between the topical application of diethanolamine (DEA) and certain DEA-related ingredients and cancer in laboratory animals. For the DEA-related ingredients, the NTP study suggests that the carcinogenic response is linked to possible residual levels of DEA. The NTP study did not establish a link between DEA and the risk of cancer in humans. DEA and DEA-related ingredients function as emulsifiers or foaming agents in cosmetics, or to adjust a products pH (acidity). Based on information filed with FDAs Voluntary Cosmetic Registration Program, it appears that DEA and DEA-related ingredients are used much less frequently in cosmetic products than they were when the NTP completed its study. Generally speaking, except for most color additives and those ingredients that are prohibited or restricted by regulation from use in cosmetics, a manufacturer may use any ingredient in the formulation of a cosmetic product provided that the ingredient and the finished cosmetic are safe, the product is properly libeled, and the use of the specific substance does not otherwise cause the cosmetic to be adulterated or misbranded under the laws that FDA enforces. FDA believes that at the present time there is no reason for consumers to be alarmed based on the use of these substances in cosmetics. However, consumers wishing to avoid cosmetics containing DEA or DEA-related ingredients may do so by reviewing the ingredient statement that is required to appear on the outer container label of cosmetics offered for retail sale to consumers. The following are some of the most commonly used ingredients that may contain DEA: Cocamide DEA Cocamide MEA DEA-Cetyl Phosphate DEA Oleth-3 Phosphate Lauramide DEA Linoleamide MEA Myristamide DEA Oleamide DEA Stearamide MEA TEA-Lauryl Sulfate Triethanolamine If FDA determines that a health hazard exists, the agency will advise the industry and the public and will consider its legal options under the authority of the Food, Drug and Cosmetic Act in protecting the health and welfare of consumers. 译文：二乙醇胺（DEA）和化妆产品NTP1998年完成的一项研究发现，DEA的适用范围和DEA的相关成分，以及实验室的动物的肿瘤之间存在着一定的关系。关于DEA的有关成分，NTP的研究表明，致癌反应的大小很可能与DEA的残留量有关。NTP的研究并没有说明DEA与人类患癌症的几率有关系。DEA和DEA的相关成分的功能，如化妆品中的乳化剂或者发泡剂，又或者用来测试产品的PH值。根据填写在FDA的化妆品配方自愿登记计划里的信息，它显示的是通常化妆品里面DEA和DEA的有关成分的用量比起NTP当年的研究是少很多的。一般来说，在化妆品里面，除了大多数色素以及那些被禁止或根据法规严格使用的成分之外，制造商在化妆品的配方中用到任何一种成份，都要确保其成分以及制成的化妆品是安全的，产品要贴上相应的标签，在FDA执行的法律下，特定物质的使用不会导致该化妆品被认为是掺假的或冒牌的。FDA相信，根据化妆品内这些物质的使用目前还没有理由让消费者警惕起来。然而，通过反复检查被要求标明在提供给零售客户的化妆品外层容器标签上的成分说明，消费者会希望化妆品里面不含DEA或DEA的相关成分。以下是一些可能含有DEA的最普遍的使用成分：椰油酰胺DEA泡沫增稠剂MEADEA