肿瘤临床试验中的常见缩略词

肿瘤临床试验中的常见缩略词ADAnalysis datasets分析数据集AEAdverse events不良事件CRcomplete response完全缓解CRFcase report form病例报告表DFSdisease free survival无病生存期DLTdose limiting toxicity剂量限制毒性DMPdata management数据管理计划DMRdata management report数据管理报告DORduration of response缓解持续时间ECethics committee伦理委员会ECOG PSeastern cooperative oncology group performance status scale东部肿瘤协作组体力状况评分EDCelectronic data capture电子数据采集FASfull analysis set全分析集FISHfluorescence in situ hybribization荧光原位杂交IBinvestigator brochure研究者手册ICFinformed consent form知情同意书INDinvesigational new drug新药临床试验申请ITTSintent to treatment set意向性分析集KPSKarnofsky performance status功能状态评分（又称卡氏评分）MTDmaximum tolerated dose最大耐受剂量NCI-CTCnational cancer institute common toxicity criteria美国国家癌症研究所通用毒性标准ORRobjective response rate客观缓解率OSoverall survival总生存期PDprogressive disease疾病进展PDpharmacodynamics药效动力学PIprincipal investigator主要研究者PKpharmacokinetics药物代谢动力学PPPer protocol符合方案PPSPer protocol set符合方案集PRpartial response部分缓解RECISTresponse evaluation criteria in solid tumors实体瘤疗效评价标准RRresponse rate缓解率SAEserious adverse event严重不良事件SAPstatistical analysis plan统计分析计划SARstatistical analysis report统计分析报告SASsafety analysis set安全性分析集SDstable disease疾病稳定SSARsuspected serious adverse reaction可疑的严重不良反应SUSARsuspected unexpected serious adverse reaction可疑的非预期的严重不良反应TTPtime to progression疾病进展时间UADRunexpected adverse drug reaction非预期药物不良反应UAEunexpected adverse event非预期不良事件ULNupper limi