氨基葡萄糖

氨基葡萄糖危险性GLUCOSAMINEDOESNOTCAUSEGLUCOSEINTOLERANCEANDHASNODOCUMENTEDEFFECTSONGLUCOSEMETABOLISM41氨基葡萄糖不会导致葡萄糖不耐症并且没有资料显示对葡萄糖代谢有影响。（ANDERSONJW,NICOLOSIRJ,BORZELLECAJFFEBRUARY2005“GLUCOSAMINEEFFECTSINHUMANSAREVIEWOFEFFECTSONGLUCOSEMETABOLISM,SIDEEFFECTS,SAFETYCONSIDERATIONSANDEFFICACY“FOODANDCHEMICALTOXICOLOGY432187201DOI101016/JFCT200411006PMID15621331STUDYFINANCIALLYSUPPORTEDBYCARGILLINCORPORATED,AMANUFACTUREROFGLUCOSAMINEASACKNOWLEDGEDINTHEPAPER）OTHERSTUDIESCONDUCTEDINLEANOROBESESUBJECTSCONCLUDEDTHATORALGLUCOSAMINEATSTANDARDDOSESDOESNOTCAUSEORSIGNIFICANTLYWORSENINSULINRESISTANCEORENDOTHELIALDYSFUNCTION424344其他对瘦弱或肥胖例子研究得出的结论是，口服标准剂量的葡萄糖不会导致或显著恶化胰岛素抵抗或血管内皮功能障碍。（MUNIYAPPAR,KARNERJ,HALLGETALNOVEMBER2006“ORALGLUCOSAMINEFOR6WEEKSATSTANDARDDOSESDOESNOTCAUSEORWORSENINSULINRESISTANCEORENDOTHELIALDYSFUNCTIONINLEANOROBESESUBJECTS“DIABETES5511314250DOI102337/DB060714PMID17065354）（POUWELSMJ,JACOBSJR,SPANPN,LUTTERMANJA,SMITSP,TACKCJMAY2001“SHORTTERMGLUCOSAMINEINFUSIONDOESNOTAFFECTINSULINSENSITIVITYINHUMANS“THEJOURNALOFCLINICALENDOCRINOLOGYANDMETABOLISM8652099103DOI101210/JC8652099PMID11344213）（BIGGEEBA,BLINNCM,NUITEM,SILBERTJE,MCALINDONTEFEBRUARY2007“EFFECTSOFORALGLUCOSAMINESULPHATEONSERUMGLUCOSEANDINSULINDURINGANORALGLUCOSETOLERANCETESTOFSUBJECTSWITHOSTEOARTHRITIS“ANNALSOFTHERHEUMATICDISEASES6622602DOI101136/ARD2006058222PMC1798503PMID16818461HTTP/WWWPUBMEDCENTRALNIHGOV/ARTICLERENDERFCGITOOLPMCENTREZINTERNATIONALJOURNALOFCLINICALCHEMISTRY3721216772DOI101016/JCCA200604014PMID16756968）（扩充GS可以刺激蛋白聚糖核心蛋白MRNA和蛋白质水平，并在同一时间从OA的关节软骨的软骨细