包礼SCulations水悬浮剂.ppt

SCformulations水悬浮剂,SuspensionConcentrates海利尔农药论坛（第十届山东省农药信息交流会）英国禾大公司www.C,SC水悬浮剂,描述：固体颗粒悬浮于水中Description:Solidparticlessuspendedinwater常见问题Issues悬浮物质与水之间存在密度差Densitydifferencebetweensuspendedmatterandwater如果原药密度大于1克/毫升将形成沉淀Willformsedimentifdensityis1如果原药密度大于1克/毫升将漂浮WillfloatifdensityisCa.i.large大粒径,HowtopreventOswaldripening怎样预防奥氏熟化的发生,较窄的粒径分布范围Narrowparticlesizedistribution还有其他的诀窍Thereareothertricks:Verylimitedamountofdilutedoilinaqueousphase将一定量的油稀释到水相中,TomakeanSC水悬浮剂制备,Preparationofsmallparticles小粒子的制备PreventingflocculationPreventingsedimentation,TomakeanSC水悬浮剂制备,Preparationofsmallparticles小粒子的制备Smallsuspendedparticlesarepreparedbymillingprocess通过砂磨设备获得较小粒径Processingconditionsareimportant生产工艺条件很重要,TomakeanSC水悬浮剂制备,Preparationofsmallparticles小粒子的制备,Wetting-Dispersion-stabilization润湿分散稳定性,Issueduringmillingprocess砂磨过程中出现的问题,Duringmillingprocessfreshsurfaceisgenerated砂磨过程中新的粒子表面产生Freshsurfaceisgenerallyofnon-polarnatureenwillclustertogetherrapidly新产生的非极性的表面通常是的自然对开很容易迅速聚集Thiscouldleadtoincreasedviscosityandevenmillblockage这可能导致粘度增加甚至阻碍砂磨进程Toovercomemillblockageawettingagentisneeded为了克服这一问题所以润湿剂的加入是非常必要的,TomakeanSC水悬浮剂制备,PreparationofsmallparticlesPreventingflocculation絮凝的预防Preventingsedimentation,Howtopreventflocculation?怎样预防絮凝的产生,Useofdispersants分散剂的使用DispersantshouldbefirmlylockedonsubstrateAnchoring锚固作用Dispersanttypes:分散剂种类Anionic阴离子Electrostaticstabilisation静电稳定作用CaDDBS/NaDDBS（十二烷基苯磺酸钙/钠）Fosfateesters（磷酸酯类）Nonionic非离子Stericstabilisation空间位阻稳定作用Alcoholetoxylates（乙氧基醇醚类）Polymericdispersants（高分子表面活性剂）MixofthetwoElectrostericstabilisation混合静电/空间位阻Naphtalenecondensatesulfonates(萘磺酸盐甲醛缩合物)Ligninsulfonates（木质素磺酸盐类）,ElectrostaticStabilization静电排斥作用,Electrostatic静电学,2dMh,G,2dp,Monomer单体-Polymer高分子,StericStabilization空间位阻作用,空间位阻是由于非离子表里面活性剂和/或高分子表面活性剂提供的Stericbarriersareproducedbyadsorptionofnonionicsurfactantsand/orpolymericsurfactant由于链的不利交叉排斥和熵值作用对重大交叠的影响Repulsionisduetounfavourablemixingofthechainsandentropiceffectsonsignificantoverlap,Functionsofsurfactants表面活性剂的功能,Wet润湿Disperse分散,Functionsofsurfactants表面活性剂的功能,Wet润湿作用Dynamicmoleculestowetsurfaceduringmillingstage在砂磨期间动态分子润湿新鲜的表面Smallermolecules分子量较小Negativeregardingstability对稳定性有负面影响Disperse分散作用Largermoleculestostabilisesuspendedparticles大分子对粒子提供稳定的悬浮支撑作用Actslow作用进程缓慢,Sizedoesmatter分子大小关系,2dMh,G,2dp,Monomer单体-Polymer高分子,StericStabilization空间位阻作用,空间位阻是由于非离子表里面活性剂和/或高分子表面活性剂提供的Stericbarriersareproducedbyadsorptionofnonionicsurfactantsand/orpolymericsurfactant由于链的不利混合排斥和熵值作用对重大交叠的影响Repulsionisduetounfavourablemixingofthechainsandentropiceffectsonsignificantoverlap,Rheologyprofilewettingagentvs.polymericdispersant润湿剂与高分子分散剂流变性特征对比,Wettingagent润湿剂,Polymericdispersant高分子分散剂,Nosheareffectpolymericdispersantflowcurve:suspensionisproperlystabilized高分子分散剂在剪切作用下的流变曲线无影响：悬浮液相对稳定Wettingagentflowcurveincreaseshugelyatlowshear:insufficientstabilisation润湿剂在低剪切作用下的流变曲线明显增大：不够稳定Ifwettingagentisrequired,useatlowpossibleconcentration!如果润湿剂是必须添加的，尽可能在最低添加量下使用,TomakeanSC水悬浮剂制备,PreparationofoildropletsinwaterPreventingcoalescencePreventingsedimentation沉淀的预防,Stokeslaw斯托克斯定律,Vs=velocityofsettling/creaming粒子沉降速度，cm/s;=viscosity水悬浮剂粘度，Pa.S;g=gravity重力加速度，cm/s;r=radiusofsphere分散介质粒子直径，cm;=densitydifferencespherepartII结晶增长,PolymericDispersant高分子分散剂,PolymericplusmonomericDispersant高分子/单体分散剂,Crystalgrowth;partII结晶增长,Effectofsurfactantmicelles表面活性剂胶体束的作用,油滴oildroplets,固体颗粒solidparticles,Crystalg