4、SCI科研论文英语写作全攻略12节视频pptw-10

酸谈学社 上海尤里卡信息科技有限公司版权所有 英语科研论文写作 第 十 章 Writing the Discussion section （1） Kevin主讲人 解 螺 旋|陪 伴 医 生 科 研 成 长 英语科研写作 The Discussion section 科研论文四部分，主要内容有哪些？. Why did you do the study? What was your hypothesis or purpose? Introduction What did you do?Methods What did you find? Results What do your findings mean? Discussion 解 螺 旋|陪 伴 医 生 科 研 成 长 英语科研写作 涵盖内容 Discussion里写什么内容？ 如何安排这些内容？ 陈述你的conclusions 展示研究成果的重要性 将本研究成果与别人的成果加以联系和比较 策略性地论述本研究的缺陷 Addressing your study limitations in a positive way 陈述本研究在临床/基础中启示/意义 Discussion需要传递的信息 解 螺 旋|陪 伴 医 生 科 研 成 长 英语科研写作 Discussion传递的信息 陈述主要结论：Stating Your Conclusions 阐述以下信息： 对主要结果的解释 本研究的结果在已发表论文中地位 创新性和卓越之处Novelty or exceptional strengths of your study 本研究的缺陷和合理的质疑Limitations or valid criticisms of your study 本结论能否延伸至更大的范畴？ 结论是否回答了the knowledge gap？ 本研究能否导致科学思维或医学实践的新变革？ 进一步研究的新途径？ 解 螺 旋|陪 伴 医 生 科 研 成 长 英语科研写作 Discussion写作顺序/模版 Addressing gap in Knowledge Conclusions Interpretation of results Novelty Generalization of conclusions? Limitations Implications/ significance Future studies Re-cap Stating Your Conclusions 解 螺 旋|陪 伴 医 生 科 研 成 长 英语科研写作 Stating conclusions 第一件事：在你的结果基础上高度概括你的结论 重要：和你的hypothesis相互呼应 解 螺 旋|陪 伴 医 生 科 研 成 长 英语科研写作 Stating conclusions 例如，在introduction的末尾我们写 到： “To further the understanding of the role of CFTR gene dysfunction in the development of the cystic fibrosis phenotype, we extensively analyzed CFTR genes in 74 patients with nonclassic cystic fibrosis who were referred for confirmatory genetic diagnosis.” 那么我们在Discussion的开头应该这 么写： “The identification of mutations in the CFTR gene in a large fraction of our patients confirms the involvement of this gene in non-classic cystic fibrosis. Indeed, each of the 29 patients with two identified CFTR mutations had at least one mutation that was predicted to be associated with residual CFTR function.” 解 螺 旋|陪 伴 医 生 科 研 成 长 英语科研写作 Stating conclusions Introduction的末尾： The goal of the current study was to investigate the role of PTK7 in the oncogenic progression of esophageal cancer. Specifically, we evaluated the expression of PTK7 in esophageal cancer by Oncomine expression and IHC analyses. Given the fact that the esophageal cancer biomarkers are scarce for clinical use, our ongoing work on PTK7 has significant implications in the diagnosis and treatment of this cancer. Discussion的开头： In this study, we found that PTK7 plays an oncogenic role in esophageal squamous cell carcinoma by negatively regulating the apoptosis. In light of Oncomine expression analysis and IHC staining results, we confirmed that PTK7 is overexpressed in clinical esophageal squamous cell carcinoma tumors. These observations lead us to test the role of PTK7 in tumor cell proliferation and migration, the hallmarks of tumorigenesis and metastasis. Indeed 解 螺 旋|陪 伴 医 生 科 研 成 长 英语科研写作 Stating conclusions （方法型论文） Introduction的末尾： The purpose of this work was to develop a rapid, reliable, and high-throughput DNA microarray method for the detection of clinically relevant carbapenem-resistant genes, including KPC, NDM- 1, OXA-23, OXA-48, OXA-51, IMP, VIM, and DIM. DNA microarrays have wide applications, including gene expression analysis, single nucleotide polymorphism detection, disease diagnosis, and pathogenic microorganism detection. It is featured by high-throughput, manageability, and automatization. Therefore, we anticipate that the microarray-based method can offer an effective method to detect the carbapenemase-producers. Discussion的开头： In this study, we developed a novel microarray method to detect carbapenem genes. The specificity, sensitivity, and reproducibility of the proposed method are suitable for clinical applications. The microarray method could detect the clinical strains carrying various carbapenemase genes. Most importantly, the microarray results showed high degrees of consistency with those obtained from Sanger sequencing or antibiotic susceptibility tests. 解 螺 旋|陪 伴 医 生 科 研 成 长 英语科研写作 Stating conclusions Hypothesis: We hypothesized that the Q gene is associated with life span in mice. Finding: Seventy percent of the mice not expressing the Q gene lived 1 year longer than the mice that expressed the gene. Conclusion: The Q gene is associated with life span in mice. Even Better: The Q gene is associated with shorter life span in mice. 解 螺 旋|陪 伴 医 生 科 研 成 长 英语科研写作 Stating conclusions Purpose: The goal of our study was to determine the toxic effects of drug X in patients with advanced solid tumors. Finding: In our study, 20 of 25 patients developed hand-foot syndrome after exposure to drug X. Conclusion？Eighty percent of patients treated with drug X develop hand-foot syndrome. 解 螺 旋|陪 伴 医 生 科 研 成 长 英语科研写作 Stating conclusions Purpose: The goal of our study was to determine the toxic effects of drug X in patients with advanced solid tumors. Finding: In our study, 20 of 25 patients developed hand-foot syndrome after exposure to drug X. Conclusion？Eighty percent of patients treated with drug X develop hand-foot syndrome. Good Conclusion: Our results indicate that hand-foot syndrome is a toxic effect of drug X. Tips for Writing Conclusions 解 螺 旋|陪 伴 医 生 科 研 成 长 英语科研写作 01 First sentence of Discussion! 03 动词时态 一般现在时 02 精确、高度概括结果 并呼应hypothesis 04 一般是一句话：本 研究的主要问题 解 螺 旋|陪 伴 医 生 科 研 成 长 英语科研写作 Poorly written Discussion Previous data suggested that BRCA1/2 mutation status influences the clinical characteristics and outcome in breast and ovarian cancers. However, mutations in these genes alone are unlikely to account for all of the variation observed; tumor formation results from an accumulation of somatic genetic alterations in several different g