三唑类杀菌剂竞争分析.ppt

技术部叶承道,三唑类杀菌剂竞争分析,甾醇生物合成抑制剂作用方式研究概况,1974抑制蛋白质合成1975抑制生物氧化作用1980抑制甾醇合成1980麦角甾醇8-7异构化作用1981麦角甾醇14-还原作用1981麦角甾醇C14-脱甲基作用,麦角甾醇生物合成抑制剂(EMIs),14(15)还原酶/8(7)异构酶抑制剂,A,吗啉类(Morpholines)R1=C12H25(dodemorph)十二环吗啉(1965)BASFONRR2=C13H27(tridemorph)十三吗啉(1965)BASFR3=C3H7-C6H5-C4H9(fenpropimorph)丁苯吗啉(1979)BASF烯酰吗啉,安克(dimethomorph)-(1984)Rohm&Hass,丁苯吗啉(fenpropimorph)杀菌谱,14(15)还原酶/8(7)异构酶抑制剂,B,哌啶类(Piperidines)CNRfenpropidin(Patrol)丁苯哌啶(1979)Roche-Maag,甾醇C14a-脱甲基酶抑制剂(DMIs),A,嘧啶类(Pyrimidines),NCYCCCOHNCXX=H,Y=Cl苯嘧啶醇(triarimol,Elacocide)1975EliLiiiy/DowX=Cl,Y=H氯苯嘧啶醇(fenarimol,Rubigan)1976EliLilly/DowX=F,Y=H氟苯嘧啶醇(nuarimol)1976EliLilly/Dow,A,嘧啶类(Pyrimidines)杀菌谱乐必耕(fenarimol，Rubigan氯苯嘧啶醇),B,吡啶类(Pyridines),CCClCCCOHNCCl帕里醇(Parinol)1976EliLilly/Dow,C,咪唑类(Imidazoles),CCNRNCOC3H5R=CH2CHCllC抑霉唑(imazalil,Fungflor,万得利)1972Janssen,C,咪唑类(Imidazoles),ClOC2H4OClR=CNClC3H7咪鲜胺(prochloraze,Sportak施保克)1977,Schering/AventisCFNClR=CCH2OC3H7氟菌唑(triflumizole,Trifumine,特富灵)1979,NipponSoda,C,咪唑类(Imidazoles)杀菌谱施保克(prochloraz,Sportak,咪鲜胺),D1,三唑类(Triazoles),CNNR1NCR1=CCF3三氟苯唑(fluotrimazole,Persalon,氟霉唑)1973,Bayer,D2,三唑类(Triazoles),CNNCHOCl(R)NCCC(CH3)3O三唑酮(Triadimefon,Bayleton,粉锈宁)1972,BayerCNNCHOCl(R)NCCHC(CH3)3HO三唑醇(triadiminol,Baytan,)1972,Bayer,D2,三唑类(Triazoles)杀菌谱三唑酮(tridimifon),D2,三唑类(Triazoles),R=双苯三唑醇(bitertanol)1981,BayerClR=ClCH2苄氯三唑醇(diclobutrazole)1981,ICI/Zeneca/Syngenta*多效唑(Paclobutrazol,PP333)1981ClR=ClCH烯唑醇(diniconazole,Spotless,速保利)1982,Sumitomo*烯效唑(uniconazol,Sumagic)1982,D3,三唑类(Triazoles),CNOHNCH2CR2NCR1R1=ClC2H4,R2=(CH3)3C戊唑醇(tebuconazole,Raxil,立克秀,Folicur)1981,BayerFR1=F,R2=粉唑醇(flutriafol,Imapact)1983,ICI/Zeneca/SyngentaClR1=Cl,R2=nC4H9己唑醇(hexaconazole,Anil,安福)1985,ICI/Zeneca/Syngenta,D3,三唑类(Triazoles)杀菌谱立克秀(tebuconazol,Raxil,Folicur戊唑醇),D3,三唑类(Triazoles)杀菌谱安福(hexaconazole,Anvil,己唑醇),D4,三唑类(Triazoles),CNCNNCH2CR2NCR1R1=,R2=nC4H9咪菌腈(fenapanil,Sisthan)1976,Rohm-HaasR1=Cl,R2=nC4H9腈菌唑(myclobutanil,Systhane,仙生)1981,Rohm-HassR1=,R2=CF3C2H4唑菌腈(propanenitrile,RH7592)1988,Rohm-Hass,D5,三唑类(Triazoles)杀菌谱仙生(Myclobutanil,Systane,腈菌唑),D5,三唑类(Triazoles),ClCNNCH2CR2NCOOCCR1R1=CH3-甲环唑1978,Ciba/Novartis/SyngentaR1=C2H5-乙环唑(etaconazole)1978,Ciba/Novartis/SyngentaR1=n-C3H7丙环唑(propiconazole,Tilt)1979,Ciba/Novartis/SyngentaClR1=CH3-,R2=-C-O-Cl苯醚甲环唑(difenoconazole,Score,世高)1983,Ciba/Novartis/Syngenta,D5,三唑类(Triazoles)杀菌谱敌力脱(propiconazole,Tilt,丙环唑),D5,三唑类(Triazoles)杀菌谱世高(difenoconazole,Score),D5,世高(Score)对蔬菜白粉病(Erysiphe白粉菌)(Sphaerotheca单丝壳菌)和(Leveillula鞑靼内丝菌)的效果,D5,世高(Score)对蔬菜黑斑病(Alternaria链格孢菌)的效果,D5,世高(Score)对蔬菜褐斑病(Cercospora尾孢菌)和斑枯病(Septoria壳针孢菌)的效果,D6,三唑类(Triazoles),CNCH3NCH2SiFNCF氟硅唑(flusilazole,Nustar,福星)1984,DuPont,D6,福星(flusilazole,Nustar)杀菌谱,D7,三唑类(Triazoles),环氧菌唑(epoxiconazole,Opus)75-125gai/ha-1986,BASF氟喹唑(fluquinconazole,Casteller)100-200gai/ha-1986,Rhone-poulenc/Aventis氟醚唑(tetraconazole,Arpege)50-100gai/ha-1987,AgrimartCo.羟菌唑(metconazole)30-90gai/ha-1987,日本吴羽呋菌唑(furconacole)50-100g