jshx英文模版开头单页

1、英文标题新罗马体4号加粗，Haaa eeee nnnn sssssLiu Linlin 1, Du Jian 1, Xiao Feng 1, Chen Li2 and Yao Pingjing 1* (小 4 号，Arial 体)(1.小单位 Institute of Chemical Systems Engineering, 上级单位 Dalian University of Technology, 市 Dalian 116012, 省 Liaoning, China)(2. School of Environment&Chemical Engineering, Dalian Univers

2、ity, Dalian 116622, Liaoning, China)Abstract: A method based on Time Slice Model (TSM ) is proposed for batch processes heat exchanger network synthesis taking place.英文摘要约15行，较详细写明研究目的、具体方法、简述过程及结果(可用数值表述)、结论及创新内容，实际用途等。一般用过去时、被动态写英文。文章最好改写成满页，不要空半页。单倍行距，8磅，新罗马体Keywords: batch processes, heat exchan

3、ger network, pseudo-temperature approach1In troducti onSOX4, a member of the C subgroup of the SOX protein family, is expressed in a wide range of tissues and involved in many developmental processes.In the study, we sequenced the SOX4-gene HMG-box in lung cancer tissues and identified mutation site

4、s 13. Despite the characterization of the function of the SOX4 protein has been引言部分要求写明研究背景，包含扼要简述历史与现 在进展状况；目前尚存在的问题，以及作者的研究意义。 文字叙述要求简明扼要，抓住重点内容和突岀问题。正文单倍行距，小5号，新罗马体，段前空4个字符注意符号、正斜体的修改要求：变量斜体，单位正体，单位前加/斜线后如 果是一组则加英文方式的()，不能出现2个 斜线。数字和单位之间空1格；% %(57) cm1-2参考文献Received 2012-04-16; Revised 2012- 05-2

5、6Foundationitem: Supported by the Scientific Research Fund of Hunan Provincial Education Department (No. 09A091). Author information: Yi Ling (1983 - ), Female, Master, Speciality: Physical Chemistry, E-mail: . Tutor: Wang Xueye (1963- ), Male, Prof essor, Ph.D. SupervisorE-mail:avera

6、ge RMS=0.15 nm, it indicates that the modeling structures were reliable for the predicted tertiary structures of SOX4.3.2 Tertiary structures of muta nt and no rmal SOX43 Results级标题小4号罗马体，上空9.6磅，下空6磅3.1 二级标题罗马体，5号字，加粗3.1.1 三级标题 罗马体，5号字The initial tertiary structures of SOX4 protein were modeled usin

7、g SOX2 as templates.TARGET59 IKRPMN AFMVWSOiLR EtklMF.QSPDM I9NAE.ISKRLG KRWfcLLKMDIgtUb|dTaavkrpfnn QtlrnwirkmiMjenpkm hn-ssiskTl j:TARGEThhhhhh血hiihhtihhhhhh hWhhhhIgNJDhhhhdililihhhhhiihhhhhh lilihhhhUsing Visualization tool of MATLAB, analysis shows that the Table 2 Comparison表题英文8磅字号新罗马体 of the

8、 total annualcosts of HENS got by pinch approach.结尾加句点英文 T min=36 KUtility cost/($?)Investment1cost/($/a )Total annual cost/($?-)139 213115 520154 7332154 095227 822381 9173549 820308 375858 1954146 345106 336252 681总计889 472758 0531647 526TARijEilFig.3 The alignment results of protein sequences of

9、SOX4 and SOX2.11()5 KIPI-IRKIEH LRI.KHMADYP IJVK ElBkkV k4弓krptideakr Irslhrnlcchp dykyriprrkl K-TARGEThhbtitilhhhhh hhhhMihhIgjODhhMihhhhhh hhhhhlihh 表格中上线与下线均为1磅线；中间要的线为 0.25磅线中文表头段前0.5行的距离栏目标题不能空白，表的英文标题结尾用句点.表中，英文 Times New Roman 6号字2J52 JO1020304050I 85LSO1.751.70IM1.601.551.5001020304Q50Fig.4

10、The variation of the total energy (a) and total potential energy (t) during perform the 50 ps MD optimization for the modeling structure.图题英文8磅字号新罗马体 Scheme for the jet reactor.结尾加句点有坐标轴的图：宽必须为 6 cm （指上图中050之间的距离）；图画线高4 cm图画布大小高 5 cm宽8 cm图要求有单位符号说明，Times New Roman新罗马体字号7pt （点），中文6号字宋体，如/（kJ mol-1）Mo

11、reover, the CA (carbon alpha) congruence between the template structures (SOX4) and the crystallogram of 1GT0 (SOX2) were performed based on VMD program, and the(A)(B)Fig.6 Stability of mutant (A) and normal SOX4 (B). Tertiary structures are shown in the space-fill mode. Green represents the side-ch

12、ain conformation of mutant and normal SOX4.4 Discussi onProteins play key roles as vital components in cellular mutant and normal forms of the SOX4 protein (Fig.7). The topology of the N/C cavity suggests that either organic molecules or protein-partners could interact with this region, and it has a

13、lso been suggested that interactions between SOX4 and cellular metabolites could impact function.5 Con clusi onThe predicted results show that human SOX4 like a flexible protein, whose activity (or function) is modulated through changes in the positions of amino acid side-chains that are essential f

14、or molecular binding and stabilization. In summary, it is likely that mutant SOX4 may result in another regulator-related disorder, affecting the regulation of the related tumor suppressor gene, resulting in lung carcinogenesis. Further studies are necessary to test this hypothesis and are currently

15、 underway.Acknowledgment (新罗马体，小 5号)The studies were supported by the National Scienee Foundation of China (39880032), the Youthful Teacher Foundation of Anhui Provinee (2006jql235), the Science Foun dati on of Huan gsha n Uni versity (2007xkjq026) and the Innovative Foundation of PhDs of Shanghai U

16、niversity.(新罗马体，6号)References:(新罗马体，小5号，加粗)1 van de Wetering M, Oosterwegel M, van Norren K H. Clevers, Sox-4, an Sry-like HMG box protein, is a transcriptional activator in lymphocytes. EMBO J, 1993 12(10):3847-3854.2 Ahn S G, Cho G H, Jeong S Y, Rhim H, Choi J Y, Kim I K. Identification of cDNAs f

17、or Sox-4, an HMG-Box protein, and a novel human homolog of yeast splicing factor SSF-1 differentially regulated during apoptosis induced by prostaglandin A(2)/Delta(12)-PGJ(2) in Hep3B cells. Biochemical Biophysical Res 1999, 260(1):216-221.统一悬挂缩进2个字符参考文献要求内容准确，注意空格、标点（新罗马体，6号，结尾加句点）1 作者姓名缩写（中文名可不缩写

18、），作者2 and作者3. 文章名（第一字母大写其余小写）.刊名（每个主词第1 字母大写），年，卷（期 ）：页项.2 作者.书名（每个主词第1字母大写）.版本.岀版地： 岀版社，岀版年.2 作者.文章名/会议名，年：页项.（文章名黑体，小3号字，左齐，注意删除注解内容及不属于本文的内容）陈启龙1,2，郑文岭2,3,马文丽2,3,*,吕顺清1（1.黄山学院生命与环境科学学院，安徽，黄山,245021; 2.上海大学电子生物技术研究中心 ，上海,200072; 3.南方医科大学 基因工程研究所，广东，广州,510515）摘要：SOX家族与很多人类肿瘤的发生有关。 对人类肺癌组织中的SOX4进行测序，发现该基因HMG-box区有突变发生并导致SOX4蛋 白的107密码子发生突变。以三级结构已知的SOX2为模板，采用同源建模方法对突变和正常 SOX4蛋白HMG-box进行建模.结果显示突 变和正常SOX4蛋白的三级结构很相似，且突变导致107密码子位置的侧链结构不稳定.提示该位置的不稳定可能会影响突变 SOX4蛋白侧 链的弹性，并有可能影响相应蛋白的功能。标准 GB6447-86?文摘编写规则？，字号8磅，宋体，英文 Times New Rom