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1、Ins of immunopharmo & immunotha1 The Journal of ImmunologyThe Journal of Immunology T T淋巴细胞淋巴细胞 Ins of immunopharmo & immunotha2 The Journal of ImmunologyThe Journal of Immunology 第二节第二节 T T淋巴细胞的表面分子及其作用淋巴细胞的表面分子及其作用 Ins of immunopharmo & immunotha3 The Journal of ImmunologyThe Journal of Immunology

2、 Ins of immunopharmo & immunotha4 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha5 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha6 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha7 The Journal of

3、 ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha8 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha9 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha10 The Journal of ImmunologyThe Journal of Immunology Ins of imm

4、unopharmo & immunotha11 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha12 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha13 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha14 The Journal of Immuno

5、logyThe Journal of Immunology Ins of immunopharmo & immunotha15 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha16 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha17 The Journal of ImmunologyThe Journal of Immunology Ins of immunoph

6、armo & immunotha18 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha19 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha20 The Journal of ImmunologyThe Journal of Immunology 第一节第一节 T T细胞的分化发育细胞的分化发育 Ins of immunopharmo & immunotha21 T

7、he Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha22 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha23 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha24 The Journal of ImmunologyThe Journal of Immuno

8、logy Ins of immunopharmo & immunotha25 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha26 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha27 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha28 The Jo

9、urnal of ImmunologyThe Journal of Immunology 第三节第三节 T T淋巴细胞的亚群淋巴细胞的亚群 Ins of immunopharmo & immunotha29 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha30 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha31 The Journal of ImmunologyT

10、he Journal of Immunology Ins of immunopharmo & immunotha32 The Journal of ImmunologyThe Journal of Immunology 特征特征 TCR多样性多少 分布 外周血60%-70%5%-15% 组织外周淋巴组织皮肤表皮和粘膜上皮 表型 CD2CD3100%100% CD4+CD8+60%-65%1% CD4-CD8+30%-35%20%-50% CD4-CD8-5%50% 识别抗原8-17个氨基酸组成的肽 HSP，脂类，多糖 提呈抗原经典MHC分子MHC I类样分子 MHC限制性有无 辅助细胞Th细胞

11、无（？） 杀伤细胞CTL细胞gdT杀伤活性 Ins of immunopharmo & immunotha33 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha34 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha35 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & i

12、mmunotha36 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha37 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha38 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha39 The Journal of ImmunologyThe Journ

13、al of Immunology Ins of immunopharmo & immunotha40 The Journal of ImmunologyThe Journal of Immunology 第四节第四节 T T淋巴细胞的功能淋巴细胞的功能 Ins of immunopharmo & immunotha41 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha42 The Journal of ImmunologyThe Journal of Immunology Ins

14、 of immunopharmo & immunotha43 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha44 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha45 The Journal of ImmunologyThe Journal of Immunology Ins of immunopharmo & immunotha46 The Journal of

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