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1、The portion of the breast that extends toward or into the underarm or axilla is referred to as the axillary tail of the breast or the tail of Spence. 乳房延伸至腋下部分称为腋尾。乳房延伸至腋下部分称为腋尾。Axillary tail(Tail of Spence)第1页/共22页有一层结缔组织称为乳腺浅有一层结缔组织称为乳腺浅筋膜筋膜, , 它覆盖乳腺实体组织它覆盖乳腺实体组织. . 乳房位于胸腔前表面乳房位于胸腔前表面, , 被下被下面的肋骨和
2、肌肉支撑面的肋骨和肌肉支撑. .在乳在乳腺的下方是胸小肌腺的下方是胸小肌. . 胸小肌胸小肌是较小是较小, , 位置较深的肌肉位置较深的肌肉. . 在乳房的旁侧和后侧的较宽在乳房的旁侧和后侧的较宽的胸大肌的胸大肌. .A layer of connective tissue called the superficial fascia of the breast surrounds the parenchyma of the breast. The breast lies on the anterior surface of the thoracic cage supported by the
3、underlying ribs and muscles. Immediately deep to the breast are the pectoralis muscles. The pectoralis minor is a smaller more deeply situated muscle. The pectoralis major muscle is a broad muscle that lies adjacent and immediately posterior to the breast. 胸大肌背阔肌锯前肌指状突起腹外斜肌第2页/共22页The pectoralis maj
4、or and minor muscles are both surrounded by a layer of fascia referred to as deep fascia. The superficial layer of the deep fascia of the pectoralis major muscle is in contact with the deep layer of the superficial fascia that surrounds the breast. These two surfaces normally glide over one another
5、allowing a womans breast to move. If anything were to occur that prevented this type of normal motion the breast becomes immobile and is referred to as “fixed”. Specifically, this situation may occur if a cancer grows from the breast into these layers. 胸大肌和胸小肌被深筋膜包胸大肌和胸小肌被深筋膜包裹。裹。胸大肌深筋膜的表面接触到胸大肌深筋膜的
6、表面接触到包裹乳腺的浅筋膜的深层。包裹乳腺的浅筋膜的深层。Pectoralis major fascia胸大肌筋膜Pectoralis majorMuscle胸大肌Superficial fascia(deep layer)深层浅筋膜Superficial fascia(superficial layer)表层浅筋膜Retromammary space乳后间隙第3页/共22页The arterial blood supply to the breast originates from branches of the axillary, internal thoracic and subclav
7、ian arteries. The venous drainage of the breast empties into branches of the internal thoracic, axillary and intercostal veins.乳腺血供来自腋窝、胸内和乳腺血供来自腋窝、胸内和锁骨下动脉。静脉引流自胸锁骨下动脉。静脉引流自胸内、腋窝和肋间静脉。内、腋窝和肋间静脉。锁骨下动静脉腋静脉腋动脉胸内动静脉分支第4页/共22页Lymph is a fluid that filters between the cells of tissue and then drains into
8、 its own set of transport channels. Lymph fluid may carry infectious organisms, toxins or cancerous cells. The channels that carry the lymph fluid are referred to as lymphatics. These lymphatics usually travel near or with the vascular supply of a tissue. Small lymphatics drain into larger lymphatic
9、s and eventually all the lymphatic fluid empties into one of the large veins in the thoracic cavity. Along the course of these lymphatic channels are soft tissue structures called lymph glands or nodes. The lymph glands act as filters to remove harmful substances from the lymph fluid. 淋巴是在组织间进行过滤的液体
10、淋巴是在组织间进行过滤的液体, , 它流它流入自己的输送渠道入自己的输送渠道. . 淋巴液载送感染性淋巴液载送感染性有机物有机物, , 毒素和癌细胞毒素和癌细胞. . 载送淋巴液的载送淋巴液的渠道称为淋巴管。渠道称为淋巴管。 这些淋巴管通常在组这些淋巴管通常在组织周围流动并且将组织维管联结。织周围流动并且将组织维管联结。 小的小的淋巴管流入大的淋巴管,淋巴管流入大的淋巴管, 并且最终所有并且最终所有的淋巴液流入胸腔的某个大血管。的淋巴液流入胸腔的某个大血管。 在这在这些淋巴管道的路程中有一些软组织称为些淋巴管道的路程中有一些软组织称为淋巴腺或淋巴结。淋巴腺或淋巴结。 这些淋巴结象过滤这些淋巴结
11、象过滤器一样过滤淋巴液中的有害物质。器一样过滤淋巴液中的有害物质。Lymph nodesLymphatics第5页/共22页The majority of the lymphatic fluid from a breast drains to the ipsilateral axilla. The axilla is rich in both lymphatic channels and lymph nodes. A small portion of the lymphatic drainage from the inferomedial breast parenchyma will drai
12、n to the lymphatic system associated with the internal thoracic vessels. 乳腺的大部分淋巴液流入腋窝淋乳腺的大部分淋巴液流入腋窝淋巴。巴。 腋窝富含淋巴管和淋巴结。腋窝富含淋巴管和淋巴结。小部分乳腺内下侧淋巴液引流入小部分乳腺内下侧淋巴液引流入胸内脉管的淋巴系统。胸内脉管的淋巴系统。 Parasternal (internal thoracic) nodesSubclavian (apical axillary) nodesInterpectoral(Rotters) nodesCentral axillarynodesB
13、rachial (lateral axillary)nodesSubscapular (posterior axillary)nodesPectoral (anterior axillary)nodes第6页/共22页For convention the axillary lymph nodes are divided into three groups:1.Pectoral or level 1(inferior to pectoralis minor attachment)第一站淋巴结(胸小肌下)2. Central or level 2(posterior to pectoralis m
14、inor attachment)第二站淋巴结(胸小肌后)3. Apical or level 3(superior to pectoralis minor attachment)第三站淋巴结(胸小肌上)第7页/共22页It is believed that the majority of the lymph drainage from the breast toward the axilla travels to the level 1 axillary nodes then to the level 2 axillary nodes and then to the level 3 axill
15、ary nodes. 普遍认为大部分的乳腺的腋窝淋巴引普遍认为大部分的乳腺的腋窝淋巴引流都是从第一站到第二站到第三站。流都是从第一站到第二站到第三站。 第8页/共22页The glands of the breast are arranged into collections called lobules. The secretions of the glands of each lobule drain into a tube called a lobular duct.乳房的腺体结合成小叶乳房的腺体结合成小叶. . 小叶腺体的分泌物流入小叶管小叶腺体的分泌物流入小叶管LobuleLobul
16、ar duct第9页/共22页Many lobules together form a lobe of the breast. The duct that carries the secretions from all the lobules in a lobe is referred to as a lobar duct. 许多个小叶汇聚成乳叶许多个小叶汇聚成乳叶. . 小叶分泌物汇小叶分泌物汇聚流入乳管聚流入乳管. .Lobar ductLactiferous sinus(ampulla)Lobe第10页/共22页A breast contains 15-18 lobes and ther
17、efore 15-18 lobar ducts. The lobar ducts are also referred to as lactiferous ducts. Each lactiferous duct has an opening on the surface of the nipple. There is a dilated region in each lactiferous duct just deep to the surface of the nipple. This dilated area is referred to as the ampulla.一个乳房有一个乳房有
18、15-1815-18个乳叶和个乳叶和15-1815-18个乳管个乳管. . 乳管也称为乳汁输乳管也称为乳汁输送管送管. . 每个乳汁输送管在其乳头处有一个开口每个乳汁输送管在其乳头处有一个开口. . 在乳头深处在乳头深处, , 每个乳汁输送管都有一个膨胀部位每个乳汁输送管都有一个膨胀部位, , 称为壶腹称为壶腹. .Lobular ductLobar duct(Lactiferous duct)LobuleAmpullaNipple第11页/共22页Over time, due to factors scientist poorly understand, the cells in the b
19、reast lobules and ducts may undergo changes. Some of these changes increase a womans risk of developing breast cancer while other changes are cancerous. To understand these changes lets look at a duct in cross section. This view is what it would be seen if a piece of breast tissue were removed from
20、the breast and then examined under a microscope.随着时间推移随着时间推移, , 由于某些无法解释的原因由于某些无法解释的原因, , 乳腺小叶和乳管会发生乳腺小叶和乳管会发生变化变化. . 有些变化会增加妇女罹患乳腺癌的风险有些变化会增加妇女罹患乳腺癌的风险. . 而有些变化本身就而有些变化本身就是癌变是癌变. . 要了解这些变化要了解这些变化, , 让我们来看一看乳腺的横截面让我们来看一看乳腺的横截面. . 第12页/共22页 In a normal duct the cells lining the duct will be one or tw
21、o layers thick. These cells will have similar size and shape.正常的乳管有正常的乳管有1 12 2层细胞。这些细胞有相似的大小和形状层细胞。这些细胞有相似的大小和形状第13页/共22页In some women, extra cells will grow in the duct. The latin term for excess is hyper and the term for growth is plasia , so a condition with excess growth is referred to as hyper
22、plasia. In this case the specific term would be ductal hyperplasia This condition confers no increase risk for developing breast cancer.有些妇女,乳管内生长了额外的细胞。这称为增生,乳管内增生。有些妇女,乳管内生长了额外的细胞。这称为增生,乳管内增生。乳管内增生第14页/共22页Sometimes the excess growth within the duct includes some very abnormal or atypical cells. T
23、his condition is referred atypical ductal hyperplasia or ADH. The presence of this condition in a womans breast increases her risk of developing a breast cancer in her lifetime. Individually, these atypical cells may resemble cancer cells. The more abnormal and atypical an individual cell the more i
24、t resembles a cancer cell. 有时,额外的细胞包括不正常或不典型的细胞。这些细胞增加了妇有时,额外的细胞包括不正常或不典型的细胞。这些细胞增加了妇女得乳腺癌的风险。单个来说,这些不典型细胞类似癌细胞。女得乳腺癌的风险。单个来说,这些不典型细胞类似癌细胞。不典型增生第15页/共22页If there are many atypical cells the entire duct may be filled with these abnormal, atypical cells. This condition is actually an early breast canc
25、er. It is referred to as ductal carcinoma in situ or DCIS. Theoretically, the cancer cells are only located within the duct and have not spread out of the affected duct. Some physicians refer to this condition as a “pre-cancer”. This is incorrect, this is indeed a localized breast cancer.如果乳管内有许多不典型
26、细胞,直至整个乳管都充满了不正常不典型的细胞。这其实是如果乳管内有许多不典型细胞,直至整个乳管都充满了不正常不典型的细胞。这其实是早期的乳腺癌。称为乳管内原位癌。早期的乳腺癌。称为乳管内原位癌。乳管内原位癌 DCIS第16页/共22页If DCIS is not treated the cancer cells will eventually break out of the duct and invade the breast tissue. This is referred to as invasive ductal carcinoma. 如果原位癌没有得到治疗,癌细胞会最终突破乳管,侵犯乳腺组织。称为浸润性乳管癌。如果原位癌没有得到治疗,癌细胞会最终突破乳管,侵犯乳腺组织。称为浸润性乳管癌。浸润性乳管癌第17页/共22页If excess growth occurs in the lobules the condition is referred to as lobular hyperplasia. Atypical lobular hyper
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