10脑脊液检查

1、10脑脊液检查clinical laboratory manualthe tenth chapter is cerebrospinal fluid examinationindex: section 1: physical examination, section second: chemical examination, third: microscopy, section fourth: other examinationssection 1: physical examinationcolor meaning of cerebrospinal fluidnormal cerebrospi

2、nal fluid is colorless red uniform for subarachnoid hemorrhage: yellow for hemorrhage, or brain tumors, cerebral embolism, severe jaundice, carotenemia; white is common in meningococcal meningitis caused by streptococcus, bacillus in green; pseudomonas aeruginosa infection; black or brown in melanom

3、a of central nervous system.two. significance of cerebrospinal fluid transparencythe normal csf is clear and transparent the puncture injury was red meningeal micro mixing; cerebrospinal fluid such as there exist cells or bacteria can be more turbid, such as purulent meningitis when cell number can

4、be increased, the milky white haze: tuberculous meningitis cells showed a moderate increase of frosted glass micro mixing; viral encephalitis, syphilis encephalitis is transparentthree, the significanee of cerebrospinal fluid coagulationnormal cerebrospinal fluid does not produce coagulation.1. mass

5、ive coagulation: seen in purulent meningitis2. coagulation: cerebrospinal fluid concentration caused by spinal cord tumor or subarachnoid space obstruction.3. film coagulation: more common in tuberculous meningitisfour 、 significance of cerebrospinal fluid densityincreased infl animat io n.five 、 si

6、gnificanee of cerebrospinal fluid phinflammation often decreasessecond section: chemical examinationi. significance of pan test of cerebrospinal fluidpositive in all kinds of meningitis, encephalitis, cerebral hemorrhage, subarachnoid space obstruction and bleeding, multiple neuritis, deformation of

7、 spinal diseasestwo、 significance of glucose determination in cerebrospinal fluid1., increased in: diabetes, japanese encephalitis, viral meningitis, polio, stroke, brain tumors2. reduce in: purulent meningitis, tuberculous meningitis, fungal meningitis, subarachnoid hemorrhage, primary or metastati

8、c meningeal tumor and so on.three significance of chloride determination in cerebrospinal fluid1., tuberculosis meningitis, purulent meningitis, fungal meningitis, polio, toxic encephalitis, brain tumors, such as cerebrospinal fluid chloride has been reduced to varying degrees2. uremia, nephritis, s

9、erous meningitis can increasethird section: microscopic examinationfirst, the significance of cerebrospinal fluid cell countinflammation of the central nervous system increasestwo. classification of cerebrospinal fluid cells1. red blood cell increase: in the ventricles of brain or subarachnoid hemor

10、rhage2. neutroph订s: seen in purulent meningitis, tuberculous meningitis, epidemic meningitis, acute phase, as we 11 as tumor metastasis, ventriculography, cerebral vascular thrombosis, and many times after lumbar puncture, etc3. lymphocyte proliferation: in viral meningitis, tuberculous meningitis,

11、fungal meningitis, syphilitic meningitis,and multiple sclerosis, drug-induced encephalopathy, sarcoidosis, multiple neuritis, peripheral artery inf lamination, and green - barre syndrome 4. macrophages: common in tuberculous meningitis and fungal meningitis5. tumor cell leukemia cells: found in brai

12、n tumors and meningeal leukemiathree, cerebrospinal fluid bacterial smear examinationfirst, the gram staining examination significance, gram positive is pneumonic diplococcus, the chain fungus, the negative is meningitis diplococcustwo, acid fast staining test positive, mostly mycobacterium tubercul

13、osissection fourth: other checksfirst, the significance of li wensheng test of cerebrospinal fluidfor the differential diagnosis of tuberculous meningitis and purulent meningitistwo 、 significance of cerebrospinal fluid syphilis test negative (agglutination). in the positive syphilis of central nerv

14、ous system infection.three, the significance of cerebrospinal fluid immunoglobulina 1. increase in igg is seen in multiple sclerosis, subacute sclerosing encephalitis, tuberculous meningitis, syphilitic meningitis, and chorea;2. iga increase is found in purulent or tuberculous meningitis, neurogenic

15、 syphilis, tumor, etc；the presence of 3. igm suggests central nervous system infection in the near futurefour 、 significance of glutamic acid amide test in cerebrospinal fluidliver cirrhosis and hepatic coma increased significantly, while hemorrhagic meningitis patients increased slightly.five、 sign

16、ificance of lactate dehydrogenase in cerebrospinal fluidcerebrospinal fluid (csf) ldh increased in different degrees in patients with meningitis, subarachnoid hemorrhage, meningeal leukemia, brain tumors and so on.six, cerebrospinal fluid tryptophan determination significancethe appearance of colorless, transparent cerebrospinal fluid tryptophan was positive, most of which were tuberculous meningitisseven 、 significance o