生物技术与化学工业可持续发展

1、生物技术与化学工业可持续发展ONCln NHONH2NOHNH2NOHNH2NH3Backman rearrangement reactionDL-AminocaprolactamCH=CHCOOHCH2CHNH2COOHRCHCHRRCH2C*NH2HR加氨酶加氨酶CCOOHHRRCCOORHRRC*COOHHRRCCOOHHRRCOHRRCORC*OHHRRCCNHNH2RCCNHO HRCC O O HHNH2RCC O O HHO HR水解酶CORRC*OHRRHRROORROOHSCHCHCCH3OSCHCHCCH3OHNHNCH2CHCHONH2NHNCH2CHCH2OHNH2NH

2、NCH2CHCHONH2ClNHCOONNOHHClNHCOKetone derivative of inabenfide(s)-inabenfideAgonomycetales sp.yield: 98%optical purity: ca 100%CH3AcOOCH3OOHCH3OAcOCH3OHOmicroorganism or enzymeONH2ROHOHH2O3POO* Conventional agar dilution method was employed using potato-sucrose medium. MICs were observed after 72 hou

3、rs incubation.TautomycetinCH3OHCH3CH3CH3OOOOOHCH3OHOOOCH3The conventional agar diution method was used. Medium: potato sucrose agar.OOSNHONH2OHOHHOOCCOOHONHNHONHOOONH2ONH2NH*1（丁基氨基甲酰）（丁基氨基甲酰）2苯并咪唑苯并咪唑NHOONHNNHNHSNHNHNHNHOOOONHONHOHOOCOHOHCH3NHONHOOOOOCH3CH3ONHCH3ONHONOCH3NHOCH3CH3HHNHCH3OCH3OHCH3NHN

4、HNR1R2OOCH3OHOHCH3OCH3OHOOHOHOHCH3OHCH3OHOHOHOCOOHRS-22 A: R1=H, R2=HRS-22 B: R1=CH3, R2=HRS-22 C: R1=CH3, R2=CH3OHCH2OHOOHCH2OHOHOHOHNHOCH2OHOHOHOHOOOOOOOHCH3CH3HHHCH3OCH3CH3MeOMeOR4HHOR3HOHCH3HC2H5CH3OR4OOOOOOOOR2OCH3CH3CH3CH3R1R3ONOOOMeOMeOMeOHMeOMeMeOHOOHOOMeMeR1234567891011121314151617181920212

5、223242526272829303132333534363738394041424344OOHOHHNaOOCOHOHOOOHOOHHOOOHOOHHOOOHOOHHOCH3OHCH3OOOCH3OHOOOOHCH3CH3HOOCH3CH3HCH3CH3CHCNNH2RCHCNOHRCH2CHCNCHCNNH2RCHOHNH2CNCHCOOHNH2RCHCOOHOHRCHCNNH2RCH2CHCOOHCHOHNH2COOHNCNNCONH2NCNNCONH2NCNNCONH2NNCNNNCONH2SCNSCONH2OCONH2OCNNCH2CNNCH2CONH2RCHCNOHRCHCONH2OHRCHCOOHOHRCHCNNH2RCHCOOHNH2RCHCONH2NH2RCHCNCH3RCHCOOHCH3RCHCONH2CH3CH3CH3CNCH3CH3CONH2CHClCNCHClCONH2CHOHCNNH2CHOHCOOHNH2CHOHCNCHOHCOOHCNCONH2CNFFFFCONH2CNNH2NH2C