生物分离工程概述第一章

1、话说天下大势，分久必合，合久必分The general trend under heaven is that there is bound to be unification after prolonged division and division after prolonged unification. Text and Other References Required Related Issues: Advances in Biochemical Engineering/Biotechnology; Bioprocessing Journal; 中国生物工程杂志 .Homework a

2、nd lecture talks are the keys to success here, despite the relatively low direct value in grade weighting. Without serious effort on the these, the exams will be very difficult. Ref: Johansson,H.O., Persson, J., Tjerneld， F., Thermoseparating water/polymer system: A novel one-polymer aqueous two-pha

3、se system for protein purification，Biotechnology and Bioengineering, 1999, 66(4), 247-257 Bioseparation is vital part of the whole Biotechnology 生物分离（生物分离（Bioseparation）是生物技术的是生物技术的重要组成部分重要组成部分！生物分离过程生物分离过程产物的提取产物的提取产物的浓缩产物的浓缩产物的纯化产物的纯化产物的精制产物的精制Effective ways to get useful bioproducts（获得产品的有效途径）（获得

4、产品的有效途径）Methods and tools of biological science and technology research原材料原材料产物产物生物分离生物分离Process of Bioproducts Engineering 预处理预处理生物反应生物反应LinkLink2.desired products in dilute suspension（悬液中的目标产物浓度低）（悬液中的目标产物浓度低）products Concentration g/l Antibiotics 25 Amino acids 100 Ethanol 100 Organic acids 100 E

5、nzymes 20 r-DNA protein 10 in g/L * Ethanol from fermentation.Rectifying columnPurifying columnBeer stillFermenter * Citric acid manufacture * Penicillin production.Production of bakers yeastProduction of monosodium glutamateRecovery of an extracellular enzymeRecovery of intracellular enzymesRecovery of penicillinRecovery of single-cell prot