重组人骨形态发生蛋白 7作用机制 - Medchemexpress - MCE中国

1、Product Data SheetRecombinant Human Bone Morphogenetic Protein 7Cat. No.: HY-P7008Synonyms: rHuBMP-7; OP-1Species: HumanSource: E. coliAccession: P18075Gene ID: 655Molecular Weight: Approximately 15.7 kDaPROPERTIESAA SequenceS T G S K Q R S Q N R S K T P K N Q E A L R M A N V A E N S S S D Q R Q A C

2、 K KS N V I L K K Y R N M V V R A C G C HH E L Y V S F R D L GWQ DW I I A P E G Y A A Y Y C E G E C A F P L N S Y MN A T N H A I V Q T L V H F I N P E T V P K P C C A P T Q L N A I S V L Y F D D SBiological Activity Data is not available.Appearance Lyophilized powder.Formulation Lyophilized after ex

3、tensive dialysis against solution in 30% acetonitrile, 0.1% TFA.Endotoxin Level 0.2 EU/g, determined by LAL method.Reconsititution Reconstitute the lyophilized recombinant Human Bone Morphogenetic Protein 7 (rHuBMP-7) to 0.1-1.0 mg/mL using10mM HAc.Storage & Stability Lyophilized recombinant Human B

4、one Morphogenetic Protein 7 (rHuBMP-7) is stored at -20C. After reconstitution, itis stable at 4C for 1 week or -20C for longer. It is recommended to freeze aliquots at -20C or -80C for extended storage.Shipping Room temperature in continental US; may vary elsewhere.DESCRIPTIONBackground Bone morpho

5、genetic protein-7 (BMP-7) is a homodimeric glycoprotein that belongs to the transforming growthfactor beta (TGF) superfamily, functions in osteogenesis and chondrogenesis, and is involved in various cellularprocesses such as kidney and eye development, brown adipogenesis, and bone metastasis. Recomb

6、inant HumanBone Morphogenetic Protein 7 produced in Chinese hamster ovary (CHO) cells is approved for revision posterolaterallumbar spine fusion and for the treatment of long bone nonunion fractures after successful clinical trials1.Page 1 of 2 www.MedChemEREFERENCES1. Yoon S, et al. Overproduction of recombinant human bone morphogenetic protein-7 in Chinese hamster ovary cells. Protein Expr Purif. 2016 Apr;120:87-91.McePdfHeightCaution: Product has not been fully validated for medical applications. For research use only.Tel: 400-820-3792; 0