BD-AcAc-2-Ketone-Ester-DataSheet-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEBD-AcAc 2Cat. No.: HY-15344CAS No.: 1208313-97-6Synonyms: Ketone Ester分式: CHO分量: 176.21作靶点: Reactive Oxygen Species作通路: Immunology/Inflammation; Metabolic Enzyme/Protease; NF-B储存式: Pure form -20C 3 years4C 2 yearsIn solvent -80C

2、 6 months-20C 1 month溶解性数据体外实验 DMSO : 50 mg/mL (283.75 mM)H2O : 33.33 mg/mL (189.15 mM; ultrasonic and heat to 60C)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 5.6750 mL 28.3752 mL 56.7505 mL5 mM 1.1350 mL 5.6750 mL 11.3501 mL10 mM 0.5675 mL 2.8375 mL 5.

3、6750 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄清的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液，建议您现现配，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (14.19 mM); Clear solution2. 请依序添加每种溶剂： 10%

4、DMSO 90% (20% SBE-CD in saline)1/2 Master of Small Molecules 您边的抑制剂师www.MedChemESolubility: 2.5 mg/mL (14.19 mM); Clear solution3. 请依序添加每种溶剂： 10% DMSO 90% corn oilSolubility: 2.5 mg/mL (14.19 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 BD-AcAc 2通过喂可提升动物液中酮体，降低糖，胰岛素和瘦素。REFERENCES1. DAgostino DP, et al.

5、 Therapeutic ketosis with ketone ester delays central nervous system oxygen toxicity seizures in rats. Am J PhysiolRegul Integr Comp Physiol. 2013 May 15;304(10):R829-36.2. Kashiwaya Y, et al. A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in amouse model of Alzheimers disease. Neurobiol Aging. 2013 Jun;34(6):1530-9.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;