Loteprednol-Etabonate _Glucocorticoid Receptor Agonist - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemELoteprednol EtabonateCat. No.: HY-17358CAS No.: 82034-46-6分式: CHClO分量: 466.95作靶点: Glucocorticoid Receptor作通路: GPCR/G Protein储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO : 45 mg/mL (96.37 m

2、M)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.1416 mL 10.7078 mL 21.4156 mL5 mM 0.4283 mL 2.1416 mL 4.2831 mL10 mM 0.2142 mL 1.0708 mL 2.1416 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。BIOLOGICAL ACTIVITY物活性 Loteprednol Etabonate具有抗炎活性，可于眼科学。REFERE

3、NCES1. Noble S, Goa KL. Loteprednol etabonate: clinical potential in the management of ocular inflammation. BioDrugs. 1998 Oct;10(4):329-39.1/2 Master of Small Molecules 您边的抑制剂师www.MedChemE2. Szelenyi I, Hochhaus G, Heer S et al. Loteprednol etabonate: a soft steroid for the treatment of allergic di

4、seases of the airways. DrugsToday (Barc). 2000 May;36(5):313-20.3. Howes JF. Loteprednol etabonate: a review of ophthalmic clinical studies. Pharmazie. 2000 Mar;55(3):178-83.4. Pavesio CE, Decory HH. Treatment of ocular inflammatory conditions with loteprednol etabonate. Br J Ophthalmol. 2008 Apr;92(4):455-9.5. Comstock TL, Decory HH. Advances in corticosteroid therapy for ocular inflammation: loteprednol etabonate. Int J Inflam.2012;2012:789623.6. LoteprednolMcePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 021-589559