Racanisodamine _mAChR Antagonist - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemERacanisodamineCat. No.: HY-N2064CAS No.: 17659-49-3分式: CHNO分量: 305.37作靶点: mAChR作通路: GPCR/G Protein; Neuronal Signaling储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO : 125 mg/mL (409.34 mM)*

2、means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 3.2747 mL 16.3736 mL 32.7472 mL5 mM 0.6549 mL 3.2747 mL 6.5494 mL10 mM 0.3275 mL 1.6374 mL 3.2747 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄清的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作

3、液，建议您现现配，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.08 mg/mL (6.81 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.08 mg/mL (6.81 mM); Clear solution3. 请依序添加每种溶剂： 10% DMSO 90% corn oil1/2

4、Master of Small Molecules 您边的抑制剂师www.MedChemESolubility: 2.08 mg/mL (6.81 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 Racanisodamineanisodamine 的种消旋体，者药理作类似。Racanisodamine 种选择性的muscarinic 拮抗剂，为近视控制滴眼液的有效成分 1。REFERENCES1. Chen Z, et al. Effects of 0.05% racanisodamine on pupil size and accommodation. Optom Vis Sci. 2010 Dec;87(12):966-70.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax