Glycopyrrolate-Glycopyrrolate-bromide-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEGlycopyrrolateCat. No.: HY-17465CAS No.: 596-51-0Synonyms: Glycopyrrolate bromide; Glycopyrronium bromide分式: CHBrNO分量: 398.33作靶点: mAChR作通路: GPCR/G Protein; Neuronal Signaling储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 mo

2、nths-20C 1 month溶解性数据体外实验 H2O : 45 mg/mL (112.97 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.5105 mL 12.5524 mL 25.1048 mL5 mM 0.5021 mL 2.5105 mL 5.0210 mL10 mM 0.2510 mL 1.2552 mL 2.5105 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。BIOLOGICAL AC

3、TIVITY物活性 Glycopyrrolate(Glycopyrronium Br)是竞争性毒蕈碱拮抗剂，可解痉挛。REFERENCES1/2 Master of Small Molecules 您边的抑制剂师www.MedChemE1. Haddad, E.B., et al., Pharmacological characterization of the muscarinic receptor antagonist, glycopyrrolate, in human and guinea-pigairways. Br J Pharmacol, 1999. 127(2): p. 413-

4、20.2. Neverlien, P.O., et al., Glycopyrrolate treatment of drooling in an adult male patient with cerebral palsy. Clin Exp Pharmacol Physiol,2000. 27(4): p. 320-2.3. Olsen, A.K. and P. Sjogren, Oral glycopyrrolate alleviates drooling in a patient with tongue cancer. J Pain Symptom Manage, 1999.18(4)

5、: p. 300-2.4. Kumar, M.G., et al., Oral Glycopyrrolate for Refractory Pediatric and Adolescent Hyperhidrosis. Pediatr Dermatol, 2013.5. Garnock-Jones, K.P., Glycopyrrolate oral solution: for chronic, severe drooling in pediatric patients with neurologic conditions. PaediatrDrugs, 2012. 14(4): p. 263-9.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 021