Aloe-emodin-Rhabarberone-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEAloe emodinCat. No.: HY-N0189CAS No.: 481-72-1Synonyms: Rhabarberone; 3-Hydroxymethylchrysazine分式: CHO分量: 270.24作靶点: Autophagy作通路: Autophagy储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 Ethanol

2、: 1 mg/mL (3.70 mM; Need ultrasonic and warming)DMSO : 1 mg/mL (3.70 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 3.7004 mL 18.5021 mL 37.0041 mL5 mM - - -10 mM - - -请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。BIOLOGICAL ACTIVITY物活性 芦荟黄素(Aloe emodin)是从芦荟叶中提取出的羟基蒽醌，已被证明体外和体内

3、抗肿瘤活性。REFERENCES1/2 Master of Small Molecules 您边的抑制剂师www.MedChemE1. Huang PH, et al. Emodin and Aloe-Emodin Suppress Breast Cancer Cell Proliferation through ER Inhibition. Evid Based ComplementAlternat Med. 2013;2013:376123.2. Liu K, et al. Aloe-emodin suppresses prostate cancer by targeting the mT

4、OR complex 2. Carcinogenesis. 2012 Jul;33(7):1406-11.3. Li SW, et al. Antiviral activity of aloe-emodin against influenza A virus via galectin-3 up-regulation. Eur J Pharmacol. 2014 Sep5;738:125-32.4. Suboj P, et al. Aloe emodin inhibits colon cancer cell migration/angiogenesis by downregulating MMP-2/9, RhoB and VEGF via reducedDNA binding activity of NF-B. Eur J Pharm Sci. 2012 Apr 11;45(5):581-91.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;