抗(抑)菌剂有效成分名录(征求意见稿)

1、附件1抗（抑）菌剂有效成分名录（征求意见稿）本名录规定了用于人体完整皮肤和黏膜的抗菌剂和抑菌剂 的有效成分清单，适用于直接用于人体完整皮肤、口腔黏膜和 阴道黏膜的抗菌剂和抑菌剂。二、名词术语（一）抗菌剂 Antibacterial lotion直接接触人体完整皮肤或黏膜（不包括用于人体足部、眼 睛、指甲、腋部、头皮、头发、鼻黏膜、肛肠等特定部位），具 有一定杀菌作用且杀灭率N90%，不以治疗疾病或者改善皮肤、 黏膜的症状为目的的液体制剂。（二）抑菌剂 Bacteriostatic lotion直接接触人体完整皮肤或黏膜（不包括用于人体足部、眼 睛、指甲、腋部、头皮、头发、鼻黏膜、肛肠等特定部位

2、），具 有一定抑菌作用且抑菌率N50%，不以治疗疾病或者改善皮肤、 黏膜的症状为目的的液体制剂。（三）CAS编码chem ical abstracts service number美国化学文摘服务社为化学物质制定的登记号，该号是 检索有多个名称的化学物质信息的重要工具，是某种物质（化 合物、高分子材料、生物序列）、混合物或合金的唯一的数字 识别号码。（四）有效成分 active ingredient在抗（抑）菌剂中，对微生物具有杀灭或抑制作用的物 质。（五）禁用物质 prohibited substance在抗（抑）菌剂中禁止添加的物质，包括化学类和生物类 物质。三、成分清单非植物类抗（抑）菌

3、剂有效成分清单见下表抗（抑）菌剂有效成分清单及出处表编号中文名称英文名称CAS编码11-漠-3-氯-5,5-二甲基乙内酰脲（漠氯海因）1-bromo-3-chloro-5,5-dimethylhydantoin(bromochlorodimethylhydantoin)16079-88-222,2-亚甲基双（3,4,6-三氯苯酚）（六氯酚）2,2-methylenebis(3,4,6-trichloro-phenol)(hexachlorophene)70-30-433-甲基-4-异丙基苯酚Isopropyl Methyl Phenol3228-02-244-氯-3 -甲酚Chlorocres

4、ol59-50-75苯酚Phenol108-95-26二甲基苯酚dimethyl phenol95-87-47甲酚Cresol1319-77-38间苯二酚Resorcin108-46-39邻苯基苯酚Biphenyl-2-ol90-43-72 522 32 221001CO11 o獭 港形瑁(【)稣形尊二T【瓯 -(HZ) -那番昔*害1 霄由二霄*霄驯813-213港咏琳琳獭w-M琴didecyl dimethylammonium chlorideoctadecyl dimethyl amine oxidedodecyl trimethyl ammonium bromidedodecyl tr

5、imethyl ammonium chloridepoly(diallyl dimethyl ammonium chloride)Ammonium Glycyrrhizatedimethyl dioctylammonium chlorideBenzethonium chlorideBenzalkonium BromideBenzalkonium chloridequaternary ammonium compounds, benzyl C12-C18 alkyl dimethyl, salts with 1,2-benzisothiazol -3 (2H)-one 1,1-dioxide (1

6、:1)quaternary ammonium compounds, benzyl C12-C16 alkyl dimethyl, chloridesquaternary ammonium compounds, benzyl C12-C14 alkyl dimethyl, chloridesquaternary ammonium compounds, C12-C14 alkyl(ethylphenyl) methyl) dimethyl, chloridesquaternary ammonium compounds, di-C8-CIO alkyl dimethyl, chlorideschlo

7、roxylenol7173-51-511119-94-4112-00-526062-79-31407-03-05538-94-3121-54-07281-04-163449-41-268424-85-185409-22-985409-23-068424-95-389-83-888-04-027双癸基二甲基漠化皎didecyl dimethylammonium bromide2390-68-328西曲漠皎cetrimide8044-71-129度米芬Domiphen Bromide538-71-630六亚甲基四胺（乌洛托品）HexamethylenetetramineUrotropin/Meth

8、enamine100-97-031醋酸氯己定chlorhexidine Acetate56-95-132聚六亚甲基双服盐酸盐poly (hexamethylenebiguanide)hydrochloride32289-58-033葡萄糖酸氯己定Chlorhexidine Gluconate Solution(Chlorhexidine digluconate)18472-51-034盐酸聚六亚甲基服polyhexamethyleneguanidinehydrochloride57028-96-335苯甲酸Benzoic Acid65-85-036丙酸Propionic Acid79-09-4

9、37次氯酸Hypochlorous acid7790-92-338甘草酸Glycyrrhizic Acid1405-86-339甘草亭酸Glycyrrhetinic Acid471-53-440酪氨酸Tyrosine60-18-441柠檬酸citric acid77-92-942硼酸Boric Acid11113-50-143L-乳酸L-(+)-lactic acid79-33-444乳酸Lactic Acid50-21-545山梨酸Sorbic Acid22500-92-146H烯酸Undecylenic Acid112-38-947水杨酸Salicylic Acid69-72-748辛酸C

10、aprylic Acid124-07-249乙酸acetic acid64-19-750硬脂酰基甘草酸Stearyl Glycyrrhetinate13832-70-751苯甲酸钠Sodium Benzoate532-32-152次氯酸钙calcium hypochlorite7778-54-353次氯酸钠Active chlorine released from sodium hypochlorite7681-52-954甘草酸二钾Dipotassium Glycyrrhizate68797-35-355高镒酸钾Potassium Permanganate7722-64-756焦亚硫酸钠So

11、dium Metabisulfite7681-57-457山梨酸钾Potassium Sorbate509-00-0158H烯酸锌Zinc Undecylenate557-08-459辛酸钠Sodium Caprylate1984-06-160苯甲醇Benzyl Alcohol100-51-661三氯叔丁醇Chlorobutanol6001-64-562乙醇Alcohol (ethyl alcohol)64-17-563异丙醇Isopropyl alcohol67-63-064正丙醇Propan-l-ol71-23-865二氯异氧尿酸钠sodium dichloroisocyanurat289

12、3-78-966二氧化氯chlorine dioxide10049-04-467三氯均二苯脉（三氯卡班）3,4,4-trichloro-carbanil id/triclo carban101-20-268三氯生Triclosan3380-34-569三氯异氧尿酸trichloroisocyanuric aicde87-90-170过氧化氢Hydrogen peroxide7722-84-171过氧乙酸Peracetic acid79-21-072苯甲基氯化物2-methylbenzhydryl chloride41870-52-473过氧苯甲酰Benzoyl Peroxide94-36-07

13、4甲紫Methylrosanilinium Chloride8004-87-375碘Iodine7553-56-276聚维酮碘Povidone Iodine25655-41-877羟苯节酯Benzyl Hydroxybenzoate94-18-878羟苯丙酯Propylparaben94-13-379羟苯丁酯Butylparaben94-26-880羟苯甲酯Methylparaben99-76-381羟苯乙酯Ethylparaben120-47-882羟苯丙酯钠Sodium Propyl Parahydroxybenzoate35285-69-983羟苯甲酯钠Sodium Methyl Par

14、ahydroxybenzoate5026-62-084羟基二氯二苯酰5-chloro-2-(4-chlorphenoxy)phenol(DCPP)3380-30-185硫磺Sulfur7704-34-986硫酸羟嗟咏Oxyquinoline Sulfate134-31-687尿囊素Allantoin97-59-688硼砂Borax1303-96-489氧化锌Zinc Oxide1314-13-290乳酸依沙叩呢Ethacridine Lactate1837-57-691银离子silver7440-22-492鱼石脂Ichthammol8029-68-393溶菌酶lysozyme9001-63-294溶葡萄球菌酶lysostaphin9011-93-2四、禁用物质抗（抑）菌剂中禁止添加列入中华人民共和国药典（2015年版）（消毒防腐类药物除外）的药品及其同名原料；以 微生物、细胞、动物或人源组织和体液等为起始原材