Evenamide-NW-3509-DataSheet-生命科学试剂-MedChemExpresss

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEEvenamideCat. No.: HY-17612CAS No.: 1092977-61-1Synonyms: NW-3509分式: CHNO分量: 278.39作靶点: Sodium Channel作通路: Membrane Transporter/Ion Channel储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO : 29

2、0 mg/mL (1041.70 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 3.5921 mL 17.9604 mL 35.9208 mL5 mM 0.7184 mL 3.5921 mL 7.1842 mL10 mM 0.3592 mL 1.7960 mL 3.5921 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液，

3、建议您现现配，当天使；澄的储备液可以根据储存条件，适当保存；以下溶剂前的百分指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.42 mg/mL (8.69 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.42 mg/mL (8.69 mM); Clear solution3. 请依序添加每种溶剂： 10% DMSO 90% corn oil1/2 Mast

4、er of Small Molecules 您边的抑制剂师www.MedChemESolubility: 2.42 mg/mL (8.69 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 Evenamide (NW-3509)，种钠通道 (sodium channel) 阻滞剂，在精神病，躁狂症，抑郁和攻击性的各种啮齿动物模型中具有显著功效 1。IC50 & Target Sodium channel 1REFERENCES1. Valentina Zuliani, et al. Advances in Design and Development of Sodium Channel Blockers. Ion Channels and Their Inhibitors pp 79-115.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;F