Golotimod-hydrochloride-SCV-07-hydrochloride-DataSheet-生命科学试剂-MedChemExpresss

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEGolotimod hydrochlorideCat. No.: HY-14743BSynonyms: SCV 07 hydrochloride; Gamma-D-glutamyl-L-tryptophanhydrochloride分式: CHClNO分量: 369.8作靶点: Bacterial; STAT作通路: Anti-infection; JAK/STAT Signaling; Stem Cell/Wnt储存式: Powder -20C 3

2、yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 H2O : 125 mg/mL (338.02 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.7042 mL 13.5208 mL 27.0416 mL5 mM 0.5408 mL 2.7042 mL 5.4083 mL10 mM 0.2704 mL 1.3521 mL 2.7042 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。BIOLOGICAL

3、 ACTIVITY物活性 Golotimod hydrochloride (SCV 07 hydrochloride) 种具有抗活性的免疫调节肽，可显提抗结核治疗的功效，刺激胸腺和脾细胞增殖，并改巨噬细胞功能。Golotimod hydrochloride (SCV 07 hydrochloride)抑制 STAT3 信号传导并调节接受放疗或放疗与铂联合药的动物模型中腔粘膜炎的持续时间和严重 程度。Golotimod hydrochloride (SCV 07 hydrochloride)复发性殖器单纯疹病毒 2 型 (HSV-2) 的潜在治疗药物。IC50 & Target STAT31/2

4、 Master of Small Molecules 您边的抑制剂师www.MedChemEREFERENCES1. Rose WA 2nd, et al. An immunomodulating dipeptide, SCV-07, is a potential therapeutic for recurrent genital herpes simplex virus type 2(HSV-2). Int J Antimicrob Agents. 2008 Sep;32(3):262-6.2. Geiger JL, et al. The STAT3 pathway as a therape

5、utic target in head and neck cancer: Barriers and innovations. Oral Oncol. 2016May;56:84-92.3. Watkins B, et al. Attenuation of radiation- and chemoradiation-induced mucositis using gamma-D-glutamyl-L-tryptophan (SCV-07). OralDis. 2010 Oct;16(7):655-60.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 021-5