有机合成综合练习

1、精选文档有机合成练习题（一）1、由苯乙酸合成苯基丙二酸。2、达成以下合成：（1）CH3NH2BrNH2（2）CH3NH2H2NNH2Cl3）OH4）BrOHBrBr（5）CH3OHBr6）7）8）CH3COOHCH3NH2ClBrBrNH2NO2（9）OHCH3CH2CCH3CH3（10）O2NCl.Cl精选文档3、由乙醛合成丁酸。4、由丙烯合成丁酸。5、由乙酰乙酸乙酯合成3-甲基-2-环己烯酮。（难）6、由4-氯丁酮为主要原料合成5-羟基-2-己酮。7、由丙二酸二乙酯为主要原料合成3-甲基丁酸。8、以乙炔及必需的无机试剂为原料合成4-己烯3-醇。9、以丙烯及必需的无机试剂为原料合成2-甲基-

2、3-戊醇。10、达成以下合成：（1）OHCH2NH2OHO（2）CCH311、由醋酸合成丙二酸二乙酯。12、由乙烯、丙烯及必需的无机试剂合成3-甲基-1-丁醇。13、由乙炔为原料合成2,2-二氯丁烷。14、由乙酰乙酸乙酯合成2-戊酮。15、由4,5-二甲基环己烯合成3,4-二甲基环戊烯（无机试剂任选）。.精选文档参照答案1、BrCNCH2COOHCHCOOHKCN-乙醇CHCOOHBr2PH2O,H+CH(COOH)22、（1）CH3CH3CH3COOHHNO3H2SO4Br2/FeBr3BrBr2/FeBr3BrPCl5NO2NO2NO2OCClNH2NH2BrNH3Br2/OH-BrHCl

3、FeBrNO2NO2NH2OO（2）CH3CClCNH2Br2/OH-NH2KMnO4/H+PCl3BrNH3BrOOONHCCH3NHCCH3NHCCH3H2SO4(浓)HNO3H2SO4O2NNO2(CH3CO)2OSO3HSO3H稀H+/HONH2Fe/HClNH2O2NNO22H2NNH2（3）ClHNO3H2SO4Cl2/FeCl3Fe/HClNaNO2+HBr05NO2ClClCuBrN2+Br-Br.精选文档（4）OHOCH3OCH3OCH3OCH3(CH3)2SO4混酸Fe/HClBr2BrBrNO2NH2NH2OCH3OHNaNO2/HClH3PO2HIBrBrBrBr5）6

4、）CH3COOHCOOHCONH2KMnO4/H+Br2/Fe1.NH32.P2O5,BrBrNH2-OHN2+ClBr2NaNO2/HClH2ONaOHBr05BrBrCH3CH3CH3CH3ClHNO3NO2+无水AlCl3H2SO4,CH3CH3NO2NH2NaNO2+HCl分别NO2Fe+HCl05CH3CH3CNCH3N2+Cl-Cu2(CN)2H2OCOOHKCNH+（7）OCOOHCl2COOHNH3CH3FeCl3KMnO4ClCONH2Br2+NaOHNH2ClCl8）.HONHCOCH3浓H2SO4NH2CH3COClNCCH3浓HNO3NHCOCH3NH2NO2BrBrH

5、3+OBrBrBr2NaNO2,HClNO2NO205N2ClBrBrBrBrH3PO2NO2NO29）10）精选文档Cl2MgCH2MgClCH3CH2Clh无水乙醚OOMgBrOHCH3CCH3H+CH2CCH3CCH3CH2CH3H2OCH3浓HNO3Cl2Fe+HCl浓H2SO4NO2FeCl3NO2NH2OClClCH3CCH3OHNO3ONHCCH3O2NNHCCH3ClClH2OO2NNH2H+/HNO2CuCl2O2NClOH-05ClCl3、2CH3CHO稀NaOHH2/NiCH3CHCHCHOKMnO4/H+CH3CH2CH2COOHCH3CH2CH2CH2OHH+4、HB

6、rNaCNCHCHCHCNCH3CH2CH2COOH322CH3CHCH2CH3CH2CH2BrH2OR2O25、OO2C2H5ONaO_OCH2Br2CCH2COCH2CH32CH32CH3CCHCOCH2CH3OOOOCH3CH3CCHCH2CHCCH3(1)5%NaOH稀NaOHC(CH2)3CCOOCHCOOCH(2)H+,CH3CH32525O6、OHOOHOOMgOOCH3CCH2CH2ClHClCH3CCH2CH2ClCH3CCH2CH2Mg(CH3CH2)2OClCH3CHOOOH3+OOOH(CH3CH2)2OCH3CCH2CH2CHCH3CH3CCH2CH2CHCH3OMg

7、Cl7、COOC2H5_COOC2H5BrCH3C2H5ONaCH3CHCH3COOC2H5HCHCHCCH2COOC2H5COOC2H5CH3COOC2H5.OH-H3+OCH3CH3CHCH2COOH精选文档8、Pd/PbOHClMgCHCHCH3CH2MgClCH2CH2CH3CH2ClH2Et2OH2SO4OH-OHCH3CHCH2CHOCH3CHCHCHOCHCHCH3CHOHgSO4H+CH3CHCHCHO+CH3CH2MgClCH3CHCHCHCH2CH3CH3CHCHCHCH2CH3OMgClH2OOH9、HBrCH3CHCH2CH3CH2CH2BrH2O2MgCH3CH2CH

8、2MgBrEt2OCH3CHCH2OCH3CCH3H+CH32OH+OHOH2OCH3CHCH3+CH3CH2CH2MgBrOHCCH2CH2CH3CH3OCH3CCH3OMgBrCH3CCH2CH2CH3CH310、（1）2）OHOHCNCNH2CH2NH2OOHOHNiHBrMg1.CH3CHOBrMgBr无水乙醚2.H2OOHK2Cr2O7OCHCH3H2SO4CCH311、12、Cl2ClCNCH2NaCNCH3COOHCOOHCH2COOH红磷,hH2OCOOHC2H5OHH2CCOOC2H5H+H2CH2SO4,COOHCOOC2H5AgH2CCH2CH2CH2250OMgCH3CHCH2+HBrCH3CHBrCH3CHMgBrCH3干醚CH3.H2CCH2OCH3CHCH2CH2OH干醚2.H3+OCH3精选文档13、CHNaNH2CNaCHCH液氮林德拉催化剂HClCHCNaCHCH+H2CH2CH2CH3CH2Cl2HClClCH3CH2CH3